Surescripts
Surescripts operates the largest U.S. health intelligence network, connecting 2.32 million healthcare professionals, virtually every pharmacy, prescriber, and payer to process 30.5 billion annual data interoperability transactions and route 2.64 billion e-prescriptions. The platform monetizes via network transaction fees and value-added services (prior authorization automation, real-time prescription benefit, specialty pharmacy solutions) sold to health systems, health plans, PBMs, pharmacies, and EHR vendors.
- Company typePrivate
- Founded2001
- HeadquartersArlington, United States
- Headcount501–1,000
- GTM typeB2B
- OfferingSoftware
What Surescripts does
Surescripts operates the largest health intelligence network in the United States, connecting virtually all pharmacies, prescribers, payers, PBMs, EHR vendors, and health systems to facilitate electronic health data exchange. Founded in 2001 and headquartered in Arlington, Virginia, the company processed 30.5 billion health data interoperability transactions in 2025, connecting 2.32 million healthcare professionals and routing 2.64 billion e-prescriptions. The platform supports a portfolio of services spanning e-prescribing (EPCS, RxTransfer), medication history, real-time prescription benefit, prior authorization automation, specialty medication workflows, and clinical direct messaging, all built on NCPDP SCRIPT and HL7 FHIR standards. Surescripts was designated as a Qualified Health Information Network (QHIN) under TEFCA in April 2025, establishing a regulatory role in nationwide health data exchange infrastructure, and operates with 99.998% average network uptime.
Surescripts firmographics
Firmographics- Name
- Surescripts
- Legal name
- Surescripts, LLC
- Website
- https://surescripts.com
- Company type
- Private
- Founded year
- 2001
- Operating status
- Operating
- Headcount range
- 501–1,000 employees
- Short description
- Surescripts operates the largest U.S. health intelligence network, connecting 2.32 million healthcare professionals, virtually every pharmacy, prescriber, and payer to process 30.5 billion annual data interoperability transactions and route 2.64 billion e-prescriptions. The platform monetizes via network transaction fees and value-added services (prior authorization automation, real-time prescription benefit, specialty pharmacy solutions) sold to health systems, health plans, PBMs, pharmacies, and EHR vendors.
- Ownership category
- akta.pro rank
Surescripts industry classification
Industry- Product category
- Healthcare Interoperability / Health Information Network
- NAICS
- Pharmacy Benefit Management and Other Third Party Administration of Insurance and Pension Funds (524292)
- SIC
- Services-Computer Programming, Data Processing, Etc. (7370)
- akta.pro primary industry
- PBM Technology Platforms (ePA/eRx/Real-Time Benefit Tools) (HLAEAKAL)
- akta.pro secondary industries
- Pharmacy Benefit Management (PBM) & Formulary Management IT (HLACAKAD), Pharmacy Benefit Management (PBM) & Pharmacy Network Administration (HLAFALAI), Specialty Pharmacy Benefit Management (Specialty PBM) (HLAEAKAE)
Keywords
Where Surescripts is headquartered
LocationHeadquarters
- HQ city
- Arlington
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Surescripts business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Infrastructure, Operations, Marketing or Sales
Revenue model
- Network Transaction Fees: Surescripts charges network participation and transaction fees to healthcare stakeholders (pharmacies, health plans, PBMs, EHR vendors) for access to its interoperability network and health intelligence services. The network processes 30.5 billion transactions annually.
- Value-Added Services: Premium services including prior authorization automation, specialty medication solutions, medication history, and real-time prescription benefit tools. These are sold to health plans, pharmacies, and health systems as add-on capabilities to core network access.
Go-to-market motion2 records
Distribution channels5 records
Marketing channels6 records
Surescripts product offering
Product offeringCore offering
Surescripts operates a nationwide health intelligence network that electronically connects pharmacies, payers, PBMs, physicians, hospitals, HIEs, and EHRs for secure health information sharing. The platform processes over 30.5 billion transactions annually and offers e-prescribing, prior authorization automation, medication history, real-time prescription benefit, and clinical interoperability services across the U.S. healthcare system.
Product overview
Surescripts operates as a health intelligence network platform connecting healthcare professionals across the entire U.S. healthcare system. The core Surescripts Health Information Network processes over 30.5 billion health data interoperability transactions annually, connecting 2.32 million healthcare professionals. The product portfolio centers on e-prescribing capabilities (E-Prescribing, EPCS, RxTransfer) that route prescriptions electronically to pharmacies nationwide. Medication management solutions include Medication History for Ambulatory, Populations, and Reconciliation; Formulary; Eligibility; and Real-Time Prescription Benefit. Prior authorization solutions range from Electronic Prior Authorization to the advanced Prior Authorization Automation system and a dedicated Prior Authorization Portal. Specialty medication solutions include Specialty Medications Gateway, Specialty Patient Enrollment, and First-Fill Abandonment insights. Interoperability is enabled through Clinical Direct Messaging, National Record Locator Service, and QHIN connectivity via Interconnect for TEFCA participation. Patient-facing solutions include Script Corner for price transparency.
Differentiator
Problem solved
Functional benefit
Products and services
- E-Prescribing Electronic prescription routing capabilities enabling prescribers to send prescriptions directly to pharmacies nationwide, with 2.64 billion e-prescriptions filled in 2025.
- Electronic Prescribing for Controlled Substances (EPCS)
Quantifiable outcome
- 40% lower out-of-pocket cost for high-cost drug classes using Real-Time Prescription Benefit recommendations
- +7 more outcomes
Companies that use Surescripts
Customer profileNamed customers10 records
Segments7 records
Ideal customer profiles2 records
Surescripts technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration3 records
AI capability2 records
Feature12 records
Surescripts partnerships and signals
Strategic signalPartnerships
13 partnerships are on record, tiered secondary and core.
- eNavvisecondaryeNavvi achieved Surescripts E-Prescribing certification, enabling clinicians to access Surescripts' nationwide pharmacy routing capabilities within the eNavvi digital prescribing platform.
- TEFCA/CMS Health Tech EcosystemcoreSurescripts, designated as a QHIN under TEFCA, is among 21 networks and companies that have pledged to become CMS Aligned Networks, committing to provide data access via FHIR APIs.
- SapphireHealthsecondarySapphireHealth achieved Surescripts Medication History for Reconciliation certification for its v2026 prescriber software serving correctional facilities. Enables integration of patient medication history into workflow.
- LogiCoysecondaryLogiCoy achieved Surescripts Real-Time Prescription Benefit certification for its LogiCoy eRx platform, enabling prescribers to access patient-specific prescription coverage and cost information within their clinical workflow.
- ArcadiasecondaryPartnership to integrate Surescripts' First-Fill Abandonment insights into Arcadia's healthcare data platform for their provider customers, enabling faster interventions for patients who don't pick up prescriptions.
- GoodRxcoreExclusive partnership to incorporate GoodRx discounted cash prices alongside insurance-based pricing in Script Corner solution. Expands patient visibility into medication costs at point of prescribing through an exclusive arrangement.
- Milliman CareFlowIQsecondaryMilliman CareFlowIQ expanded its clinical intelligence platform by integrating broader medication history sourced from Surescripts, enhancing real-time insights for healthcare providers.
- WalgreenscoreWalgreens and Surescripts presented jointly on Specialty Medications Gateway at NASP Conference. Solution has achieved 85% adoption across Walgreens specialty pharmacies with 63% of users reporting it helped avoid calls to prescribers.
- CLEARcorePartnership with CLEAR's secure identity platform to enhance identity verification technology infrastructure for the Surescripts Network Alliance. CLEAR's identity proofing technology supports providers, pharmacies, and payers in streamlining identity validation.
- NACDS, APhA Foundation, NCPA FoundationcorePharmacy Workgroup sponsors along with Surescripts working to address interoperability gaps that prevent pharmacists from sharing data with other healthcare providers and payers.
- The Sequoia ProjectcoreLaunched joint Pharmacy Workgroup under Interoperability Matters program, funded and collaboratively developed with Surescripts. Surescripts co-chairs the workgroup with Point-of-Care Partners to address pharmacy interoperability gaps.
- ActiveRADAR (Acquired)coreAcquisition of ActiveRADAR, a clinical intelligence company, to enhance solutions for medication management and prescription pricing. Aims to improve medication adherence, reduce drug spend, and increase provider access to comprehensive clinical and cost data.
- Major EHR Vendors (Epic, eClinicalWorks, Cerner, Allscripts, etc.)coreExtensive partnerships with EHR vendors enabling integration of Surescripts e-prescribing, medication history, prior authorization, and interoperability services into their platforms. Over 480,000 healthcare providers have access through these integrations.
Scale indicators13 records
Recent moves6 records
Expansion highlights3 records
Surescripts competitors and assessment
Company assessmentEmerging players
- Avaneer Health: Avaneer Health is an emerging blockchain-based healthcare network launched by major payers and providers that targets provider-to-payer data exchange — an emerging peer in the same interoperability/QHIN-adjacent category as Surescripts.
Direct peers
- DrFirst: DrFirst is a direct competitor in e-prescribing, medication management, and clinical interoperability, providing EHR-integrated prescribing, medication history, and prior-authorization workflows for ambulatory providers and hospitals.
- Health Gorilla: Health Gorilla is a Qualified Health Information Network (QHIN) under TEFCA providing clinical data exchange, record retrieval, and interoperability — a direct peer in the federal QHIN framework alongside Surescripts.
- NaviNet (Zelis): NaviNet, owned by Zelis, operates a healthcare information network connecting payers, providers, and pharmacies for eligibility, claims status, and care coordination — directly comparable to the Surescripts Network Alliance model.
- CoverMyMeds: CoverMyMeds (acquired by McKesson) is the most direct competitor to Surescripts in electronic prior authorization, also serving prescribers, pharmacies, and payers with workflow-integrated PA services across the U.S. healthcare market.
- RelayHealth (McKesson): RelayHealth, part of McKesson, operates a competing pharmacy network and clinical messaging platform that routes e-prescriptions and eligibility transactions — overlapping core Surescripts rails including e-prescribing and pharmacy messaging.
Broad incumbents
- eClinicalWorks: eClinicalWorks is a major ambulatory EHR vendor integrated with the Surescripts network via National Record Locator Service and e-prescribing, but its expanding native interoperability features create competitive overlap for smaller providers.
- Change Healthcare (Optum): Change Healthcare, now part of Optum, is a broad incumbent in healthcare data exchange covering eligibility, claims, payments, and clinical interoperability — overlapping with Surescripts across eligibility, coordination of benefits, and pharmacy messaging.
- Veradigm (formerly Allscripts): Veradigm provides EHR and practice management software with integrated e-prescribing and interoperability services for ambulatory providers — a broad incumbent that competes for EHR-embedded prescribing and medication history workflows.
- Epic Systems: Epic is both a deep integration partner and a potential competitive incumbent through its Cosmos data platform, Carequality interop framework, and growing native ePA/prescribing capabilities reaching large U.S. health systems.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
Surescripts social profiles
Digital presenceSurescripts compliance and trust
Trust signalCompliance4 records
Surescripts financial estimates
Financial estimateRevenue estimate
Valuation estimate
Surescripts leadership team
Management profileNumber of profiles
Profiles4 records
Surescripts subsidiaries and ownership
Company hierarchySubsidiaries1 record
Surescripts funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Surescripts M&A and investment
M&A and investmentM&A1 record
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Surescripts
What does Surescripts do?
Surescripts operates a nationwide health intelligence network that electronically connects pharmacies, payers, PBMs, physicians, hospitals, HIEs, and EHRs for secure health information sharing. The platform processes over 30.5 billion transactions annually and offers e-prescribing, prior authorization automation, medication history, real-time prescription benefit, and clinical interoperability services across the U.S. healthcare system.
Is Surescripts a public or private company?
Surescripts is a private company. It is classified as private equity controlled and is currently operating.
When was Surescripts founded?
Surescripts was founded in 2001. It employs 501 to 1,000 people.
Where is Surescripts based?
Surescripts is headquartered in Arlington, United States, in the North America region.
How does Surescripts make money?
Two revenue lines are on record. Network Transaction Fees are the primary driver. The others are value-Added Services.
Who are Surescripts's main competitors?
Avaneer Health is listed as an emerging player. Direct peers are DrFirst, Health Gorilla, NaviNet (Zelis), CoverMyMeds and RelayHealth (McKesson). Broad incumbents are eClinicalWorks, Change Healthcare (Optum), Veradigm (formerly Allscripts) and Epic Systems.
Does Surescripts have an API?
No public API is recorded for Surescripts.
What industry is Surescripts in?
Surescripts's product category is Healthcare Interoperability / Health Information Network. Its primary akta.pro industry code is HLAEAKAL, PBM Technology Platforms (ePA/eRx/Real-Time Benefit Tools), with a secondary code of HLACAKAD, Pharmacy Benefit Management (PBM) & Formulary Management IT. Its NAICS code is 524292 and its SIC code is 7370.