WV Drug Intervention Institute

What WV Drug Intervention Institute does

The West Virginia Drug Intervention Institute (WV DII) is an independent 501(c)(3) nonprofit headquartered in Charleston, West Virginia, founded in 2019 and previously housed at the University of Charleston. Its mission is to reduce opioid and related drug misuse and deaths through prevention, education, and outreach supported by evidence-based research. The organization serves higher education institutions, K-12 school districts, public transit authorities, municipal governments, healthcare systems, and harm reduction organizations across all 50 U.S. states.

WV DII's flagship product is the ONEbox, an emergency opioid overdose reversal kit that combines two doses of naloxone, personal protective equipment, and on-demand bilingual (English/Spanish) instructional video activated when the box is opened, with a training mode for pre-emergency practice. The portfolio also includes the Nalox(ONE) WV pharmacy-based program (deployed with over 20 West Virginia pharmacies), the Don't Keep Rx Around evidence-based medication safety curriculum for pre-K and kindergarten students, the Be The One campus bystander-intervention initiative, fentanyl education resources, and a free online naloxone training course. To date, the organization has distributed more than 15,000 ONEboxes across all 50 states, with 300+ documented lives saved and 30,000+ persons trained on overdose reversal.

WV DII operates a hybrid revenue model combining grant funding (Appalachian Regional Commission, state Opioid Response funding, foundation grants), direct hardware sales of ONEbox at $199 per kit (often funded via opioid settlement dollars), and tax-deductible donations. Distribution is primarily institutional and grant-funded rather than commercial, executed through partnerships with state health departments, higher education institutions, transit authorities, and harm reduction coalitions. The organization is led by President Dr. Susan Margaret Murphy.

Name

WV Drug Intervention Institute

Legal name

West Virginia Drug Intervention Institute, Inc.

Website

https://wvdii.org

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

11–50 employees

Short description

West Virginia Drug Intervention Institute is a Charleston, WV-based 501(c)(3) nonprofit that develops the ONEbox opioid overdose reversal kit and delivers naloxone distribution, pharmacy-based, and education programs to higher education, K-12, transit, government, and harm reduction customers across all 50 states.

Ownership category

akta.pro rank

Product category

Opioid Overdose Prevention Products and Harm Reduction Services

NAICS

Outpatient Mental Health and Substance Abuse Centers (621420)

SIC

Pharmaceutical Preparations (2834)

akta.pro primary industry

Substance Use Recovery & Harm Reduction Support Services (BPAGAEAO)

akta.pro secondary industries

Pharmacovigilance, Medication Safety & Controlled Substance Diversion Monitoring (HLAFALAN), Infectious Disease & STI Testing-to-Treatment with eRx + Pharmacy Fulfillment (HLALAIAL)

Keywords

• Overdose reversal kits
• Naloxone distribution programs
• Opioid prevention education
• Harm reduction services
• Medication safety curriculum

Headquarters

HQ city

Charleston

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Marketing or Sales, Supply Chain, Others

Revenue model

1. Grant Funding: Primary revenue source from government grants including Appalachian Regional Commission INSPIRE Initiative ($498,880), State Opioid Response funding through WV DHHR, and foundation grants such as Beckley Area Foundation ($9,999).
2. ONEbox Kit Sales: Sale of ONEbox emergency overdose response kits at $199 per box. Funded by opioid settlement funds, grants, or direct purchase by organizations.
3. Donations: Tax-deductible donations to the 501(c)(3) nonprofit organization supporting overdose prevention mission.

Pricing tiers

Go-to-market motion3 records

Distribution channels6 records

Marketing channels8 records

Core offering

WV Drug Intervention Institute designs, distributes, and trains users on the ONEbox emergency opioid overdose reversal kit, a technology-enabled, wall-mounted unit containing two doses of naloxone, personal protective equipment, and on-demand bilingual (English/Spanish) video instructions activated when the box is opened. The organization also operates the Nalox(ONE) WV statewide pharmacy program, the Don't Keep Rx Around medication safety curriculum, the Be The One campus initiative, free online Naloxone Training, the KCTC community coalition, and a Fentanyl Education program.

Product overview

WV Drug Intervention Institute offers a portfolio of harm reduction and overdose prevention products and programs. The core product is ONEbox, an emergency opioid overdose reversal kit that provides on-demand bilingual video instructions and contains naloxone doses. This is complemented by the Nalox(ONE) WV pharmacy program, educational initiatives including the Don't Keep Rx Around curriculum for young children and Be The One campus prevention program, plus free online naloxone training. The organization also operates community outreach through KCTC and provides fentanyl education resources.

Differentiator

Problem solved

Functional benefit

Brands

• ONEbox: Emergency opioid overdose reversal kit designed to promote safety by providing life-saving, on-demand training when and where needed. Contains naloxone, video instructions in English and Spanish, and personal protective equipment.
• Nalox(ONE) WV
• Be the One
• Don't Keep Rx Around

Products and services

• ONEbox Emergency Opioid Overdose Reversal Kit Technology-enabled, wall-mounted opioid overdose reversal kit containing two doses of naloxone, personal protective equipment, and on-demand bilingual (English/Spanish) video instructions activated when the box is opened, plus a training mode for practice; for institutions, workplaces, and public spaces that need standardized, no-prior-training bystander response.
• Nalox(ONE) WV Statewide pharmacy-based program that empowers pharmacists to educate patients receiving opioid prescriptions, dispense naloxone, and provide DisposeRx home medication disposal packets; designed for community pharmacies, pharmacy networks (e.g., Fruth, CPESN WV, PursueCareRx), and curriculum partners (e.g., NDSU School of Pharmacy).
• Don't Keep Rx Around (DKRA) Curriculum Evidence-based curriculum and public health campaign teaching medication safety to pre-K and kindergarten students and their families throughout West Virginia; targeted at schools, early-childhood educators, and family-serving organizations.
• Be The One Initiative Overdose prevention initiative for West Virginia college campuses focused on opioid overdose prevention from a bystander's perspective, encouraging students, staff, and faculty to intervene and save a life during an overdose emergency; delivered through the West Virginia Collegiate Recovery Network, Marshall University, and the West Virginia Higher Education Policy Commission.
• Free Online Naloxone Training Free online naloxone training course teaching individuals how to properly administer naloxone during an active overdose emergency; available to the general public and institutional partners.
• KCTC (Kanawha Communities That Care) Community coalition creating a unified community response to prevent substance abuse and supporting the development of effective programs that promote a safer, healthier, and drug-free Kanawha County.
• Fentanyl Education Program Educational resources and training focused on fentanyl awareness, counterfeit pills, and the dangers of illegally manufactured fentanyl affecting youth and communities; targeted at schools, parents, community organizations, and youth-serving programs.

Quantifiable outcome

• 15,000+ ONEboxes distributed in all 50 states with 300+ lives saved
• +2 more outcomes

Named customers13 records

Segments6 records

Ideal customer profiles6 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

22 partnerships are on record, tiered core and minor.

• Baltimore (Maryland Transit Administration)coreImplementation/ SI/ Consulting Partner · 3 November 2025Partnership to install Naloxone ONEboxes in all 14 Baltimore Metro stations, both above and below ground. Boxes include reversal drug, PPE, and bilingual video instructions. Part of citywide overdose response strategic plan.
• Mobilize RecoverycoreStrategic or Co-development Partner · 29 August 2025National sponsorship of Mobilize Recovery's Campus Surge program. DII and ONEbox are national sponsors working to build a nationwide community of first responders. Campus Surge stops include donation of 50 overdose response kits in every community visited.
• New Mexico Department of HealthcoreImplementation/ SI/ Consulting Partner · 30 April 2025Statewide ONEbox program providing free Narcan kits, wall-mounted boxes, and standardized training materials to schools, businesses, tribal communities, and local governments.
• Volusia Recovery AlliancecoreStrategic or Co-development Partner · 30 April 2025Working to distribute ONEbox to 100+ Volusia County businesses to get Narcan to those who need it and help curb opioid overdoses.
• University of Tennessee Health SciencescoreImplementation/ SI/ Consulting Partner · 16 April 2025Launched naloxone training and ONEbox program on Memphis campus. Pilot training gathered interdisciplinary students for overdose recognition and naloxone administration, placing kits alongside AEDs in high-traffic locations.
• PAARI (Police Assisted Addiction & Recovery Initiative)coreStrategic or Co-development Partner · 25 February 2025Presentation at 6th Annual National Law Enforcement Summit on mobilizing law enforcement and communities for overdose prevention. Showcased ONEbox deployment with police departments nationwide.
• Southeast Utah Health DepartmentcoreImplementation/ SI/ Consulting Partner · 9 December 2024Pilot project distributing 24 ONEboxes at local businesses in Carbon and Emery counties. Health department provides naloxone training to community.
• Oneonta Narcan Initiative TeamcoreStrategic or Co-development Partner · 17 May 2024Organized ONEbox program with over 20 community organizations. Coordinated Narcan kit installation on OPT buses and business distribution.
• Bassett Healthcare NetworkcoreStrategic or Co-development Partner · 5 March 2024Population Health Office joined ONEbox initiative with Oneonta Narcan Initiative Team. ONEboxes empower bystanders to respond to overdose emergencies.
• Westbrook Partners for PreventioncoreStrategic or Co-development Partner · 30 January 2024Distributed 10 ONEboxes throughout Westbrook, Maine at schools, city hall, community center, and local businesses. Funded by city's opioid settlement funds.
• Huntington-Charleston Region Law EnforcementcoreImplementation/ SI/ Consulting Partner · 19 September 2023Partnership with law enforcement for naloxone distribution and education. ARC grant funding 10 persons in recovery to assist with law enforcement outreach.
• Murphy Innovative Solutions and Concepts / Murphy MediacoreStrategic or Co-development Partner · 6 September 2023Partnership with Murphy Innovative Solutions and Concepts and Hope in the Hills for Healing Appalachia festival. Murphy Media, owned by Joe Murphy (creator of ONEbox), produces training content and video instructions. Collaboration includes naloxone training at music festivals and ONEbox distribution. The partnership exceeded $500,000 in economic impact and trained over 11,000 attendees.
• Gibson GuitarsminorGTM or Marketing Partner · 6 September 2023Donated VIP bags and merchandise for Healing Appalachia festival naloxone training raffle.
• Hikma PharmaceuticalscoreGTM or Marketing Partner · 6 September 2023Donated 1,000 boxes (2,000 doses) of 8mg intranasal naloxone (Kloxxodo) for Healing Appalachia festival.
• West Virginia Collegiate Recovery NetworkcoreStrategic or Co-development Partner · 16 December 2022Partner with Marshall University and WV DII for Be The One initiative. Susie Mullens coordinated statewide expansion ensuring all 29 WV campuses have naloxone and ONEbox.
• Marshall UniversitycoreStrategic or Co-development Partner · 16 December 2022Partner in Be The One initiative and WV Collegiate Recovery Network. Hosted program coordination and supported campus overdose prevention efforts.
• West Virginia Higher Education Policy CommissioncoreStrategic or Co-development Partner · 16 December 2022Supported naloxone-on-campus initiative with grant funds to recruit student ambassadors for opioid misuse prevention education.
• DocStationcoreStrategic or Co-development Partner · 28 March 2022Partner with Nalox(ONE) Program, empowering pharmacists to track and evaluate program's impact in preventing and reducing opioid-related overdoses.
• North Dakota State University School of PharmacycoreStrategic or Co-development Partner · 28 March 2022Curriculum development partner for Nalox(ONE) program. Pharmacists trained using curriculum developed by NDSU School of Pharmacy, now being used in four states.
• Fruth PharmacycoreStrategic or Co-development Partner · 14 February 2022Participating pharmacy in Nalox(ONE) WV program. Pharmacists educate patients on opioid prescriptions, provide naloxone, and DisposeRx packets. Fruth President Lynne Fruth called it a proven model of medication safety important for communities.
• CPESN WV (Community Pharmacy Enhanced Services Network)coreStrategic or Co-development Partner · 14 February 2022Participating pharmacy network in Nalox(ONE) WV program. Dr. Gretchen Garofoli noted the project's novel approach puts pharmacists 'in the game to serve West Virginians.'
• PursueCareRx PharmacycoreStrategic or Co-development Partner · 14 February 2022Participating pharmacy in Nalox(ONE) WV program reaching patients with opioid prescriptions.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

Others

• Foundation for Opioid Response Efforts (FORE): Philanthropic funder of innovative opioid response programs; a likely grant-maker to WV DII and a peer in the sense of competing for the same opioid settlement funding ecosystem.
• Hikma Pharmaceuticals (Kloxxado): Maker of 8mg Kloxxado nasal naloxone, an active WV DII partner that donated 2,000 doses at Healing Appalachia; relevant as a fellow naloxone supplier/ecosystem participant.

Direct peers

• Overdose Lifeline: Indiana-based 501(c)(3) harm reduction nonprofit providing naloxone distribution, training, and recovery support — the closest direct analog to WV DII's mission and operating model with similar state-level impact scope.
• Remedy Alliance / To Save More Lives: Nationwide buyer-club distributing free mail-order naloxone to harm reduction programs; overlaps with WV DII's overdose prevention mission and competes for the same state health department and grant funding pools.
• Police Assisted Addiction and Recovery Initiative (PAARI): Nonprofit enabling law-enforcement-based addiction response; an active WV DII partner and functional peer building referral pipelines between first responders and recovery services.
• Drug Policy Alliance: Leading harm-reduction advocacy and policy organization shaping the state-level settlement funding environment that fuels WV DII's deployment contracts.

Emerging players

• Harm Reduction Therapeutics: Nonprofit pharmaceutical company that brought the first OTC generic nasal naloxone (RiVive) to U.S. shelves; competes indirectly by commoditizing the naloxone that WV DII packages into its ONEbox kits.

Broad incumbents

• Emergent BioSolutions (Narcan): Manufacturer of the leading branded Narcan nasal spray, the dominant naloxone SKU WV DII bundles inside ONEbox; defines the broader nasal naloxone supply chain and pricing environment.
• National Council on Alcoholism and Drug Dependence (NCADD): Long-standing national nonprofit addressing substance use disorder; comparable in mission and education/advocacy delivery, though broader in scope than WV DII's opioid focus.

Regional players

• McShin Foundation: Virginia-based recovery-focused nonprofit offering naloxone training, sober living and recovery employment; shares WV DII's Appalachian geography and dual overdose/recovery employment model.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xtwitter.com/westvirginiadii
• YouTubeyoutube.com/channel/UCS_ohi8zddohCtzTSkOm1Cg/featured
• Facebookfacebook.com/DIIinc
• LinkedInlinkedin.com/company/drug-intervention-institute
• Instagraminstagram.com/westvirginiadii

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds2 records

Investors2 records

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about WV Drug Intervention Institute