Flatiron Health

What Flatiron Health does

Flatiron Health is a privately held, US-headquartered healthcare technology company founded in 2012 and operating as an independent affiliate of the Roche Group since Roche's $1.9 billion acquisition in 2018. The company serves two primary customer sets: (1) life sciences organizations — biopharma clinical development, HEOR/RWE, market access, regulatory, and commercial teams across the oncology drug lifecycle — and (2) community oncology practices and academic cancer centers that deliver point-of-care oncology services. Flatiron reports that 100% of the top 20 oncology life sciences companies partner with the company, and that more than 4,700 providers across 1,600+ community oncology sites use its OncoEMR® platform.

The company combines an ONC-certified, cloud-based oncology EHR (OncoEMR®) with a clinical decision support layer (Flatiron Assist™), a multi-agent AI analytics platform (Flatiron Telescope, launched May 2026), an EHR-to-EDC connector (Flatiron Clinical Pipe™), and a Vendor Network of integrated third-party solutions. Underpinning these products is a curated real-world oncology dataset covering 5M+ research-ready patient records across the US, UK, Germany, and Japan with 15+ years of longitudinal data, plus a 150,000+ patient Clinico-Genomic Database co-developed with Foundation Medicine. AI/ML is used to extract 2.7B+ structured data points from unstructured clinical notes, and the company published the first peer-reviewed VALID Framework for LLM-extracted oncology RWD, with documented extraction accuracy within two percentage points of expert human abstractors.

Flatiron generates revenue through recurring OncoEMR subscriptions and implementation fees, multi-year RWD licensing and data subscriptions (including Panoramic datasets in hematology and prostate), custom professional services engagements (650+ to date with life sciences clients), and enterprise contracts across the drug development lifecycle. Pricing is quote-based with annual billing for OncoEMR, multi-year contracts for life sciences engagements, and pay-as-you-go for the Telescope platform. The company distributes through direct enterprise sales, direct sales to community oncology practices, self-service/PLG via Telescope, channel partners (notably Paradigm Health for clinical research), and a curated Vendor Network — supported by a major presence at oncology conferences (ASCO, ESMO, ISPOR, ASH, AACR, SABCS) and a publications footprint of 2,000+ peer-reviewed papers.

Name

Flatiron Health

Legal name

Flatiron Health

Website

https://flatiron.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

Flatiron Health is an oncology technology company that combines an ONC-certified EHR (OncoEMR®), real-world datasets covering 5M+ cancer patients, and AI-powered analytics to deliver real-world evidence to biopharma and point-of-care solutions to community oncology practices across the US, UK, Germany, and Japan.

Ownership category

akta.pro rank

Product category

Oncology Real-World Evidence Software

NAICS

Medical and Diagnostic Laboratories (62151), Computer Systems Design and Related Services (54151), Custom Computer Programming Services (541511)

SIC

Services-Computer Programming, Data Processing, Etc. (7370), Services-Medical Laboratories (8071), Services-Health Services (8000)

akta.pro primary industry

Real-World Data (RWD) Platforms & Clinical Data Curation (HLACAIAJ)

akta.pro secondary industries

Oncology Pathways & Precision Medicine Decision Support (HLACAGAH), Healthcare Terminology, Ontology & Code Set Management (SNOMED/LOINC/ICD/RxNorm) (HLACAIAF), Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D) (HLAGAJAF), De-identification, Tokenization & Privacy-Preserving Data Platforms (HLACAIAK), Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• Oncology real-world data
• Oncology EHR software
• Real-world evidence analytics
• Clinical decision support
• Oncology research platform

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices6 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D

Revenue model

1. OncoEMR® Subscription and Implementation Fees: Recurring subscription model with one-time implementation fees and annual subscription fees covering software licenses, customer support, software upgrades, and services. Additional fees apply for HL7 interfaces, data conversions, FHIR APIs, and vendor services (MaxMD, SureScripts, DrFirst).
2. Real-World Evidence and Data Licensing: Subscription and licensing-based revenue from life sciences clients accessing Flatiron's real-world oncology data, custom data solutions, clinico-genomic databases, and the Flatiron Telescope AI platform. 100% of top 20 oncology life sciences companies partner with Flatiron.
3. Custom Professional Services & Engagement Models: Professional services revenue from 650+ custom service engagements, including end-to-end support, ongoing insights, and one-time insights delivered to life sciences clients across clinical development, HEOR/RWE, regulatory, market access, and commercial teams.
4. Data Licensing and Research Collaborations: Non-exclusive data licensing agreements (e.g., immune receptor data licensing with Pfizer Inc. by Adaptive Biotechnologies via Flatiron integrations), companion diagnostic co-development, and academic/regulatory research partnerships.
5. Panoramic Dataset Subscriptions and AI-Powered Insights: Revenue from newly launched multinational Panoramic datasets (hematology, prostate) covering over 905,000 patients across US, UK, Germany, and Japan, plus AI-powered insights via Flatiron Telescope.

Pricing tiers

Go-to-market motion5 records

Distribution channels6 records

Marketing channels9 records

Core offering

Flatiron Health operates an end-to-end oncology technology platform that combines an ONC-certified cloud-based electronic health record (OncoEMR®) and clinical decision support tools (Flatiron Assist™, OncoAir®, CareSpace) for community oncology practices with one of the world's largest de-identified oncology real-world datasets (5M+ patient records, 15+ years, across US/UK/Germany/Japan) and an AI-powered analytics platform (Flatiron Telescope, VALID framework) for life sciences organizations. The platform captures structured and unstructured data at the point of care, transforms it into regulatory-grade real-world evidence using validated LLM extraction, and delivers insights across the drug development lifecycle to 100% of the top 20 oncology life sciences companies.

Product overview

Flatiron Health operates as a unified oncology technology platform combining two interconnected product lines: Point of Care Solutions for community oncology practices and Real-World Evidence Solutions for life sciences organizations. The Point of Care line centers on OncoEMR® (an ONC-certified, cloud-based EHR used by over 4,700 providers across 1,600+ community cancer care centers) and Flatiron Assist™ (an embedded clinical decision support platform), complemented by the Flatiron Vendor Network for third-party integrations (e.g., DeepScribe, Canopy, TailorMed, House Rx). The Real-World Evidence line consists of Flatiron Real-World Data (covering 5M+ patient records across US, UK, Germany, and Japan with 15+ years of longitudinal data), Real-World Evidence Insights (custom analytics services), and Flatiron Telescope (the newly launched AI-powered intelligence platform with conversational UI and multi-agent analytics). Supporting both lines is Flatiron Clinical Pipe™, an EHR-to-EDC connector for clinical trial data management that integrates with Veeva EDC. Together, these products form an end-to-end oncology ecosystem that captures real-world care data at the point of care, transforms it via AI and LLM-based extraction (validated by the VALID Framework), and delivers it to life sciences partners as regulatory-grade evidence for drug development, market access, and commercial decisions.

Differentiator

Problem solved

Functional benefit

Brands

• OncoEMR®: Cloud-based oncology-specific electronic medical record (EHR) platform used by community oncology practices across the United States; ONC Health IT Certified.
• OncoAir®
• Flatiron Assist™
• Flatiron Telescope
• Flatiron Clinical Pipe™
• Flatiron Insight
• Flatiron Vendor Network

Products and services

• OncoEMR® ONC-certified cloud-based oncology-specific electronic health record (EHR) platform used by 4,700+ providers across 1,600+ community oncology practice sites in the US; includes OncoAir® mobile app, CareSpace patient portal, NCCN Order Templates®, AJCC staging, and clinical trial surfacing; subscription-based with one-time implementation fee and annual subscription covering software, support, and upgrades.
• Flatiron Assist™ Clinical decision support platform embedded in OncoEMR® that surfaces NCCN guideline-recommended regimens, customizable practice-preferred treatment pathways, clinical trial opportunities, and prior authorization automation; demonstrated 87% clinician adoption, 88% NCCN concordance, and 2-day improvement in time to prior authorization.
• Flatiron Telescope AI-powered intelligence platform with a multi-agent adaptive analytics engine and natural language interface enabling life sciences teams to query de-identified oncology data, build patient cohorts, assess study feasibility, and generate insights without coding expertise; built on 5M+ patient records across US, UK, Germany, and Japan.
• Flatiron Clinical Pipe™ EHR-to-EDC connector that integrates Flatiron's EHR-derived oncology data with sponsor EDC systems (e.g., Veeva EDC) to eliminate manual data entry in clinical trials, reduce monitoring costs, and accelerate study timelines for community oncology and academic research sites.
• Flatiron Real-World Data (Panoramic Multimodal RWD) Subscription and licensing-based access to Flatiron's curated, de-identified oncology real-world datasets covering 5M+ research-ready patient records with 15+ years of longitudinal data across the US, UK, Germany, and Japan, integrated with genomics, imaging, pathology, and claims data; offered as hematology and prostate Panoramic datasets.
• Flatiron Real-World Evidence (RWE) Insights & Custom Services Custom professional services delivering end-to-end, ongoing, and one-time RWE/RWD insights to life sciences clients across clinical development, HEOR/RWE, regulatory, market access, and commercial functions; 650+ custom engagements delivered by a 200+ person multidisciplinary team.
• OncoAir® Mobile companion application for OncoEMR® distributed via the Apple App Store (id1527805825) that supports oncology care teams and patients in the office, on call, or during rounds.
• CareSpace Patient portal product integrated with OncoEMR® that keeps patients connected to their care team and health information, with EHR-level access for patient-facing applications and third-party integrations (e.g., HealthTree Foundation).
• Flatiron Insight Oncology point-of-care analytics product identified as a top-rated vendor in Black Book's 2026 State of Digital Healthcare in Oncology report, providing analytics for community oncology practices alongside OncoEMR.

Quantifiable outcome

• 75% of surveyed biopharma decision-makers rank Flatiron as outperforming competitors on data quality
• +11 more outcomes

Named customers12 records

Segments8 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration25 records

AI capability13 records

Feature9 records

Partnerships

32 partnerships are on record, tiered minor, flagship and core.

• Onc.AIminorStrategic or Co-development Partner · 28 May 2026Onc.AI's Onclara IO biomarker validated on Flatiron Health data in a retrospective cohort of 205 patients; demonstrates significant survival stratification beyond PD-L1 testing alone.
• Foundation MedicineflagshipStrategic or Co-development Partner · 22 May 2026Co-developed the Flatiron Health–Foundation Medicine Clinico-Genomic Database of over 150,000 patients used to support FDA companion diagnostic approvals, including FoundationOne CDx for TEPMETKO in METex14 NSCLC (Foundation Medicine's first real-world data-powered companion diagnostic approval).
• Community Oncology Alliance (COA)coreStrategic or Co-development Partner · 28 April 2026Multi-year collaboration with COA to deliver the first comprehensive real-world assessment of care in community oncology; landmark study of 98,000 patients showed community oncology survival exceeds SEER national benchmarks by 8 months (breast cancer) and 2 months (NSCLC).
• DeepScribecoreTechnology or Integration · 27 April 2026DeepScribe SmartPrep pre-visit intelligence product available on Flatiron Health's OncoEMR platform; clinicians report spending about one-third as much time preparing for each oncology patient as previously.
• AbbottcoreTechnology or Integration · 30 March 2026Abbott integrated its Precision Oncology portfolio (Oncotype DX, OncoExTra, Oncodetect, Riskguard) into Flatiron's OncoEMR® platform, enabling clinicians across 1,600+ community cancer care centers and 4,700+ providers in North America to order tests and view results within their existing clinical workflow.
• AnthropiccoreTechnology or Integration · 11 January 2026Partnership as part of Anthropic's Claude for Healthcare launch; Flatiron Health is among major life sciences partners (with AstraZeneca, Sanofi, Genmab, Banner Health, Veeva) collaborating on clinical workflows, drug discovery, and regulatory processes.
• Paradigm HealthflagshipStrategic or Co-development Partner · 4 December 2025Paradigm Health acquired Flatiron Health's Clinical Research Business and formed a multi-year strategic partnership to rebuild the clinical research ecosystem; integrates Paradigm's software into Flatiron's OncoEMR platform (used by 4,500+ providers), expanding Paradigm's network to 25+ academic medical centers, 100 community oncology practices, and 2.4M patients.
• Paradigm HealthcoreChannel Partner/ Reseller/ Distributor · 4 December 2025Designated as Flatiron Vendor Network's preferred Clinical Research Partner; exclusively focused on clinical research and uniquely aligned with healthcare providers' research priorities; rebuilding the clinical research ecosystem with AI-powered platform enabling equitable trial access.
• Caris Life SciencescoreStrategic or Co-development Partner · 1 December 2025Joint Clinical-Molecular Database partnership; presented research at SABCS 2025 using the joint database to identify genetic alterations linked to CDK4/6 inhibitor treatment resistance and a novel gene signature predicting liver metastasis risk in advanced NSCLC.
• NateracoreTechnology or Integration · 12 November 2025Integration of Natera's oncology testing portfolio into Flatiron Health's cloud-based OncoEMR platform, including Natera's Constellation cloud platform, facilitating electronic ordering and results delivery for cancer care providers.
• Adaptive BiotechnologiescoreTechnology or Integration · 2 July 2025Integration of Adaptive's clonoSEQ® MRD testing into Flatiron Health's OncoEMR® platform, enabling electronic ordering across 1,000+ U.S. clinics serving over 4,500 providers. Adaptive also signed two non-exclusive immune receptor data licensing agreements with Pfizer.
• Massive BiocoreTechnology or Integration · 25 April 2025Partnership to use Massive Bio's database for clinical trial patient recruitment, improving access to trials and clinical trial enrollment.
• Veeva SystemscoreTechnology or Integration · 16 April 2025Joined Veeva's Product Partner Program to accelerate oncology clinical research via integration of Flatiron Clinical Pipe™ EHR-to-EDC connector with Veeva EDC, eliminating manual data entry, reducing monitoring costs, and accelerating study timelines. Establishes long-term strategic forum for future innovations.
• NRG OncologycoreStrategic or Co-development Partner · 19 March 2025Collaboration leveraging Flatiron's EHR-to-EDC technology to drive more efficient clinical trials; integration of Flatiron Clinical Pipe™ with NRG Oncology's trial infrastructure.
• University of Colorado Cancer CentercoreImplementation/ SI/ Consulting Partner · 5 March 2025Collaboration to drive more efficient clinical trials using Flatiron's EHR-to-EDC technology; CU Cancer Center serves as a research site using Flatiron Clinical Pipe™.
• Exact SciencescoreStrategic or Co-development Partner · 5 February 2025Strategic partnership to advance clinical evidence generation for Exact Sciences' molecular residual disease (MRD) test Oncodetect; first patient enrolled within six months of partnership announcement, evaluating test across multiple solid tumor types in community settings.
• DeepScribecoreTechnology or Integration · 24 January 2025Partnership to bring oncology-specific ambient AI to Flatiron's 4,200+ providers; DeepScribe's SmartPrep pre-visit clinical intelligence product is available on both Ontada's IKnowMed EHR and Flatiron's OncoEMR platforms.
• LifebitcoreTechnology or Integration · 9 October 2024Partnership bringing cutting-edge research technology to Japan, advancing global cancer care through real-world data; combines Flatiron's oncology data with Lifebit's federated AI technology.
• Roche GroupflagshipStrategic or Co-development Partner · 1 January 2018Roche acquired Flatiron Health for $1.9 billion in 2018. Flatiron operates as an independent affiliate of the Roche Group, providing oncology data, technology, and point of care solutions while leveraging Roche/Foundation Medicine assets such as the Clinico-Genomic Database. Roche subsequently recorded a CHF 3.2 billion goodwill impairment and explored potential divestiture with Citigroup.
• Canopy CareminorChannel Partner/ Reseller/ DistributorFeatured Vendor in Flatiron Vendor Network; Continuous Care Platform helping care teams remotely manage patient care, optimize triage, and generate new reimbursement streams via PCM and CCM programs.
• House RxminorChannel Partner/ Reseller/ DistributorFeatured Vendor; medically integrated dispensing technology and services enabling oncology practices to stand up in-house pharmacies with pharmacy management software.
• Willowglade TechnologiesminorChannel Partner/ Reseller/ DistributorFeatured Vendor; eForms, ePROs, triage communications, telemed, itinerary reminders; improving communication, collaboration, and care plan adherence.
• Smirta InnovationsminorChannel Partner/ Reseller/ DistributorFeatured Vendor; smart schedule optimization tool helping practices maximize utilization of clinical resources, optimize patient visit schedules, and monitor clinical operations.
• RISA LabsminorChannel Partner/ Reseller/ DistributorFeatured Vendor; precision AI platform for oncology prior authorization; integration with OncoEMR in progress.
• TailorMedminorChannel Partner/ Reseller/ DistributorFeatured Vendor; end-to-end platform for financial assistance and pharmacy; connecting patients, providers, pharmacies, and life sciences companies to improve access, affordability, and adherence.
• PhreesiaminorChannel Partner/ Reseller/ DistributorVendor Hub member; digital patient registration, referral management, patient communication, PROs, and patient activation tools with live connection to at least one OncoEMR site.
• Friends of Cancer ResearchminorStrategic or Co-development PartnerCollaborative pilot project highlighting the importance of high-quality real-world data for external-control arms in cancer research, presented at ISPOR 2026.
• AstraZenecacoreStrategic or Co-development PartnerListed as a partner with Anthropic's Claude for Healthcare alongside Flatiron Health for clinical workflows, drug discovery, and regulatory processes.
• SanoficoreStrategic or Co-development PartnerListed as a partner with Anthropic's Claude for Healthcare alongside Flatiron Health.
• GenmabminorStrategic or Co-development PartnerListed as a partner with Anthropic's Claude for Healthcare alongside Flatiron Health.
• Banner HealthminorStrategic or Co-development PartnerListed as a partner with Anthropic's Claude for Healthcare alongside Flatiron Health.
• VeevacoreStrategic or Co-development PartnerListed as a partner with Anthropic's Claude for Healthcare alongside Flatiron Health.

Scale indicators19 records

Recent moves8 records

Expansion highlights7 records

Direct peers

• Tempus AI: Tempus AI is the closest direct competitor, building AI-enabled precision medicine datasets in oncology with linked clinical and molecular records, AI-driven trial matching, and life-sciences data licensing. It targets the same oncology RWE and biopharma buyer as Flatiron.
• ConcertAI: ConcertAI is a direct competitor in oncology real-world evidence and clinico-genomic data, serving life-sciences clients with research-grade datasets and AI-enabled analytics for trial design and HEOR. It is one of the few vendors with comparable oncology-specific data depth.
• Syapse: Syapse offers a precision-oncology real-world evidence platform focused on community health systems and life-sciences partners, with a focus on molecular profiling and outcomes. It competes directly with Flatiron for health-system data partnerships and pharma RWE engagements.
• Cota Healthcare: Cota Healthcare curates oncology real-world data and provides analytics for life sciences and providers, including treatment-pattern and outcomes research. It overlaps directly with Flatiron in oncology RWE and is often a competing vendor on biopharma study bids.

Broad incumbents

• IQVIA: IQVIA is the largest clinical and real-world evidence vendor globally, offering oncology-specific RWE capabilities alongside its broader life-sciences services portfolio. It competes head-to-head with Flatiron on RWE licensing and HEOR studies, though as part of a much larger services franchise.
• McKesson / Ontada: Ontada, McKesson's oncology technology and insights business, operates the IKnowMed EHR used by The US Oncology Network and competes head-to-head with OncoEMR in community oncology practices. It is also an emerging RWE competitor via its iKnowMed-derived data.
• Epic Systems: Epic is the dominant hospital EHR vendor, including at large academic cancer centers, and its Cosmos and research datasets increasingly compete with Flatiron's network. It does not specialize in community oncology, but its scale of inpatient and academic oncology data is a structural threat.

Emerging players

• Verana Health: Verana Health curates specialty real-world datasets (initially ophthalmology and neurology, expanding into oncology-adjacent areas) and provides AI-driven RWE for life sciences. It is an emerging RWE peer with partial overlap in therapeutic-area real-world evidence.
• Veeva Systems: Veeva is both a partner (Clinical Pipe integrates with Veeva EDC) and an adjacent competitor in oncology clinical-trial technology and life-sciences data infrastructure. It overlaps with Flatiron at the clinical-trial-operations layer and increasingly in life-sciences data analytics.
• Atropos Health: Atropos Health provides AI-augmented real-world evidence generation from electronic health record data and is increasingly cited alongside Flatiron for biopharma RWE studies. It is a smaller, emerging peer with a differentiated consultative AI model rather than a longitudinal curated dataset.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat8 records

Key risks6 records

Key highlights7 records

Customer concentration

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Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Subsidiaries1 record

Funding overview

Funding rounds4 records

Investors15 records

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M&A2 records

Investments4 records

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Frequently asked questions about Flatiron Health