What HBox does

HBox is a virtual-first care platform founded in 2021 that delivers AI-driven remote patient monitoring, chronic care management, and episodic virtual care services to specialty healthcare providers. The company is headquartered in Boston, Massachusetts with its corporate entity incorporated in Wilmington, Delaware (HBox Inc.), and operates with 11-50 employees. Its primary go-to-market targets cardiology, nephrology, and pulmonology practices, where it addresses the gap between episodic in-clinic visits and continuous at-home care through an integrated stack of connected medical devices (blood pressure cuffs, glucose meters, pulse oximeters, spirometers, weight scales, touchless thermometers), the HBox Health Pod in-home care kit with a 10-inch always-on display, patient and provider mobile applications, and a HIPAA-compliant cloud platform with 50+ EMR integrations. The company's core technical differentiator is time-resolved physiological monitoring—capturing hourly and minute-by-minute vital signs, medication timing, and symptom correlations—built on five years of continuous data collection and validated by peer-reviewed research including four American Heart Association scientific statement citations and the 2024 ACC/AHA Perioperative Cardiovascular Management Guidelines.

HBox monetizes through multiple recurring and transactional revenue streams: subscription-based RPM and CCM services billed under Medicare CPT codes (99453, 99454, 99457, 99458); Principal Care Management and Remote Therapeutic Monitoring for musculoskeletal and respiratory conditions; virtual episodic care billing under telehealth and e-visit codes; hardware sales and leasing of connected devices; and professional services for pharmaceutical sponsors and CROs through its decentralized clinical trial (DCT) platform, which leverages an exclusive 250,000+ Medicare patient panel, 120+ principal investigators, and 60 trial sites. Distribution runs through direct enterprise field sales targeting health systems, ACOs, and specialty practices—supplemented by an Ecosystem Partners program that recruits EHR vendors, billing companies, DME suppliers, home health agencies, pharmacies, and diagnostic labs as referral and integration channels.

The company has raised approximately $2.8M in disclosed venture funding—a $700K seed round led by Arali Ventures in April 2022 and a $2.1M follow-on in 2023—and closed a strategic growth investment from Charlesbank Capital Partners' Technology Opportunities Fund II in December 2025 to accelerate AI-powered virtual care expansion in its core specialties. HBox is founder-led by Banuprasad Dhanakoti (CEO), Mohammed Ali (CRO), and Sandeep Subramanya (COO), with Dr. Rahul Chaudhary as Chief Medical Officer, and is advised by a bench that includes a CMS/CPT Editorial Panel co-chair, a Johns Hopkins nephrology division director, and practicing specialists in cardiology and pulmonology.

Name

HBox

Legal name

HBox Inc.

Website

https://hbox.ai

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

11–50 employees

Short description

HBox is an AI-driven virtual-first care platform providing remote patient monitoring, chronic care management, and decentralized clinical trial services to specialty practices in cardiology, nephrology, and pulmonology. It serves health systems, ACOs, pharma sponsors, and CROs via connected medical devices, EMR-integrated software, and a pre-enrolled panel of 250,000+ Medicare patients.

Ownership category

akta.pro rank

Product category

Virtual Care Platform (Remote Patient Monitoring & Chronic Care Management)

NAICS

Ambulatory Health Care Services (621)

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Virtual Specialty Care Platforms (tele-stroke, tele-ICU, tele-derm, tele-cardiology) (HLALABAD)

akta.pro secondary industries

Cardiology Telemedicine Platforms (HLALAGAB), DTx/SaMD Deployment, Integration & Reimbursement Enablement (HLACANAO)

Keywords

• Virtual care platform
• Remote patient monitoring
• Chronic care management
• Decentralized clinical trials
• AI-driven healthcare

Headquarters

HQ city

Boston

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Remote Patient Monitoring (RPM) Services: Recurring subscription revenue from RPM programs enabling providers to monitor chronic patients remotely. Bills under CPT codes 99453, 99454, 99457, 99458 for physiological monitoring. HBox provides devices, platform, care coaches, and billing support.
2. Chronic Care Management (CCM): Monthly recurring revenue from CCM programs for patients with multiple chronic conditions. Bills under CCM CPT codes with care coordination and 20+ minutes of clinical staff time.
3. Virtual Episodic Care Services: Revenue from virtual consultations, e-visits, and telehealth visits. Bills under CPT codes including G2012, G2010, 99421-99423, and telehealth visit codes 9920x-9921x for synchronous video communication.
4. Connected Medical Devices: Hardware revenue from selling or leasing SIM-enabled medical devices including blood pressure cuffs, glucose meters, pulse oximeters, weight scales, and spirometers to healthcare providers and patients.
5. Decentralized Clinical Trial Services: Revenue from providing pharma sponsors and CROs with access to HBox's network of 120+ principal investigators, 60 clinical trial sites, and 250,000+ pre-enrolled Medicare patients for decentralized clinical trial recruitment and monitoring.
6. Principal Care Management (PCM) & RTM: Additional monitoring programs for single high-risk chronic conditions, plus Remote Therapeutic Monitoring services for musculoskeletal and respiratory conditions.

Pricing tiers

Go-to-market motion3 records

Distribution channels6 records

Marketing channels7 records

Core offering

HBox is an AI-driven virtual-first care platform for healthcare providers in cardiology, nephrology, and pulmonology. It combines remote patient monitoring (RPM), chronic care management (CCM), virtual episodic care, hospital-at-home, and decentralized clinical trials on a HIPAA-compliant cloud with 50+ EMR integrations and SIM-enabled connected medical devices. The company sells its platform, connected devices, and dedicated care coach services to specialty clinics, health systems, ACOs, and pharma/CRO customers.

Product overview

HBox is an AI-driven virtual-first care platform for healthcare providers specializing in Cardiology, Nephrology, and Pulmonology. The platform operates as a unified ecosystem combining: (1) a core Virtual-First Care Platform with integrated HBox Cloud infrastructure, (2) four main care delivery modules—Remote Continuous Care (RPM/CCM/RTM/PCM), Virtual Episodic Care, Virtual Hospital OS, and Decentralized Clinical Trials—and (3) a connected device ecosystem including the HBox Health Pod, Blood Pressure Cuff, Spirometer, Weight Scale, Touchless Thermometer, Pulse Oximeter, and Glucose Meter. The system is complemented by patient and provider mobile applications, certified CareCoach services, HBox Concierge support, and specialized solutions for Outpatient Clinics, ACOs, Health Systems, Ecosystem Partners, and Pharma/CROs. The platform integrates with 50+ EMR systems and leverages AI for patient engagement, progress management, predictive analytics, and workflow optimization.

Differentiator

Problem solved

Functional benefit

Products and services

• HBox Virtual-First Care Platform Comprehensive AI-driven virtual-first care platform for healthcare providers delivering remote care for chronic conditions across cardiology, pulmonology, and nephrology. Integrates real-time vital data collection, clinical documentation, care coordination, and 50+ EMR integrations on a HIPAA-compliant cloud.
• Remote Continuous Care (RPM/CCM/PCM/RTM) Remote Patient Monitoring (RPM), Chronic Care Management (CCM), Principal Care Management (PCM), and Remote Therapeutic Monitoring (RTM) module for healthcare providers managing patients with multiple or single high-risk chronic conditions. Includes full EMR integration, care coordination, and 20+ minutes clinical staff time tracking for billing.
• Virtual Episodic Care Module that transforms episodic care into measurable and monetizable interactions through virtual consultations, online services, e-visits, and medication management. Enables clinics to monetize incoming calls with seamless EHR integration and bills under CPT codes G2012, G2010, 99421-99423, and telehealth visit codes 9920x-9921x.
• Virtual Hospital OS Operating system for hospital-at-home and transitional care delivery, extending hospital care beyond facility walls. Covers pre/post surgery care, acute hospital-at-home programs, and transitional care management to reduce readmission rates (claimed 25% reduction, up to 40% hospital cost savings).
• Decentralized Clinical Trials (DCT) Decentralized trial platform for clinical research with remote patient assessments and virtual engagement. Enables pharma sponsors and CRO partners to recruit from a 250,000+ patient pool, conduct remote assessments, and exceed recruitment targets via 60 clinical trial sites nationwide.
• HBox Health Pod 10-inch always-on display in-home virtual care kit with integrated medical devices and built-in cellular connectivity. Features AI-driven UI and serves as a single window to all virtual care services for patients at home.
• HBox Blood Pressure Cuff SIM-enabled blood pressure monitoring device that automatically tracks and transmits blood pressure readings to physicians, ready to use out of the box with wireless data transmission requiring no patient action.
• HBox Spirometer FDA-cleared Bluetooth and mobile app compatible spirometer for measuring peak flow, FEV1, and PEF. Uses pressure sensor technology making it less susceptible to damage from debris, dirt, or mucus; intended for pulmonary remote monitoring.
• HBox Weight Scale Remote-connected weight tracking device for automatic weight monitoring from home, ready to use out of the box with wireless connectivity to the HBox platform.
• HBox Touchless Thermometer Advanced IR sensor forehead and ear infrared thermometer for instant body temperature readings. Suitable for all ages and designed for personal, medical, or batch screening use.
• HBox Pulse Oximeter SIM-enabled pulse oximeter for monitoring chronic respiratory conditions such as asthma, COPD, chronic bronchitis, and congestive heart failure. Automatically transmits oxygen saturation data wirelessly to the HBox platform.
• HBox Glucose Meter SIM-enabled glucometer for automatic blood glucose measurement and transmission. Ready to use out of box with wireless data transmission to physician portals, used for diabetes, kidney disease, gestational diabetes, obesity, and geriatrics monitoring.
• HBox Patient Healthcare SuperApp Patient mobile application providing vitals tracking (BP, weight, glucose), appointment scheduling, doctor messaging, prescription refills, medical history, and RPM/CCM care program enrollment with AI chatbot support.
• HBox Doctor App Provider-facing tablet application providing a bird's eye view of medical adherence, patient test results, insurance claims history, and program enrollment. HIPAA compliant with state-of-the-art encryption.
• Outpatient Clinics Solution Vertical solution package for outpatient clinics to monitor and manage chronic conditions across pulmonary, cardiology, nephrology, and primary care specialties using the HBox virtual-first care platform.
• ACOs Solution Vertical solution enabling ACOs to achieve quality improvement goals, cost reduction, and risk mitigation through virtual-first care services across participating provider networks.
• Health Systems Solution Vertical solution providing transitional care management, hospital-at-home programs, and pre/post surgery care for health systems and hospitals, with claimed outcomes of 25% readmission rate reduction and up to 40% savings in direct hospital costs.
• Ecosystem Partners Program Partner program for revenue cycle management, EMR platforms, medical device manufacturers, diagnostic labs, imaging centers, pharmacy, DMEs, home health, billing companies, and healthcare suppliers to integrate with or refer customers to HBox.
• Pharma & CRO Services Clinical trial services for pharma sponsors and CRO partners with access to 250,000+ pre-enrolled Medicare lives, 120+ registered principal investigators, and 60 sites nationwide.
• HBox Clinical Research Clinical studies conducted by participating physicians for drug development. Partners with pharma, biotech, and CROs across MI, IL, and AZ with studies for migraines, diabetes, acne, depression, high cholesterol, and vaccine research.
• CareCoach Services Certified care coaches providing patient engagement with chronic and disease management expertise, working alongside AI tools with regular patient interactions. Coaches are evaluated using the proprietary CareCoach Effort Units (CEU) model.

Quantifiable outcome

• 25% reduction in hospital readmission rates for health system customers
• +3 more outcomes

Named customers2 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

AI capability10 records

Feature7 records

Partnerships

Three partnerships are on record, tiered strategic and core.

• InfoBionic.AistrategicTechnology or IntegrationHBox.ai and InfoBionic.Ai formed a partnership to offer the first AI-driven 'Cardiology Clinic of the Future' combining HBox's virtual care platform with InfoBionic.Ai's cardiac monitoring technology.
• Velocity Clinical ResearchcoreTechnology or IntegrationHBox Clinical Research operates under oversight from Velocity Clinical Research and adheres to FDA standards set by Velocity for decentralized clinical trial operations.
• Velocity Clinical ResearchcoreStrategic or Co-development PartnerClinical trials conducted by HBox Clinical Research are overseen by participating physicians and held to standards set by the FDA and Velocity, a leading clinical research organization.

Scale indicators8 records

Recent moves6 records

Expansion highlights3 records

Direct peers

• Cadence: Specialty-focused RPM and care management platform with deep cardiology and nephrology presence — a direct head-to-head competitor for HBox's specialty clinic segment and shared specialty RPM/CCM CPT code strategy.
• Biofourmis: AI-driven RPM and virtual care platform with predictive analytics focused on chronic conditions and hospital-at-home — directly comparable to HBox's time-resolved monitoring and Virtual Hospital OS capabilities.
• Vivify Health: A direct competitor offering an RPM and virtual care platform targeting health systems and providers with connected devices, patient engagement tools, and chronic condition management — overlapping with HBox's Remote Continuous Care and Virtual Episodic Care offerings.
• Caregility: Inpatient-focused virtual care platform with telehealth hardware and software for health systems — comparable to HBox's Virtual Hospital OS and health system solution offerings.
• AMC Health: Long-standing RPM and telehealth provider serving health systems, payers, and ACOs with continuous monitoring and care coordination — overlapping with HBox's value-based care and ACO solutions.
• Health Recovery Solutions (HRS): Direct peer providing RPM software and connected devices to hospitals, ACOs, and specialty practices for chronic care management and transitional care — closely aligned with HBox's RPM/CCM and Hospital-at-Home modules.
• Propeller Health (ResMed): Respiratory digital health leader with FDA-cleared connected inhaler sensors and COPD/asthma management — directly competes with HBox's pulmonology focus and connected spirometer/pulse oximeter device offering.

Emerging players

• Optimize Health: RPM software-as-a-service platform serving specialty practices and provider groups with connected device kits and chronic care management workflows — comparable in scale and customer profile to HBox.
• CoachCare: RPM platform targeting specialty and primary care practices with connected devices and remote monitoring services — emerging competitor in the same mid-market specialty clinic segment as HBox.

Broad incumbents

• Omada Health: Established digital chronic care platform spanning diabetes, hypertension, and behavioral health — broader portfolio but overlaps with HBox on cardiology/diabetes RPM and value-based care delivery models.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/get_hbox
• Facebookfacebook.com/profile.php
• LinkedInlinkedin.com/company/hboxai

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds2 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about HBox