MediStream
MediStreams provides healthcare payment and remittance automation software that converts paper EOBs, electronic remittances, and lockbox payments into standardized posting files for health systems, ambulatory practices, DME suppliers, and channel partners. It serves 750+ clients and integrates with 51 banks and 44 clearinghouses.
- Company typePrivate
- Founded2009
- HeadquartersRoswell, United States
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What MediStream does
MediStreams is a healthcare payment and remittance automation company founded in 2009 and headquartered in Roswell, Georgia. The company operates the Cascade Product Suite, a platform that automates the full payment lifecycle for healthcare providers — from medical lockbox intake and paper EOB conversion through ANSI 835 posting files, EHR delivery, and reconciliation to general ledger close. The platform processes payments arriving via lockbox, PDF, and EDI, applies AI-powered OCR and NLP for correspondence classification (30+ document types at 99% accuracy), and matches EFTs to ERAs to deliver funded posting files with a 24-hour SLA. It is bank-agnostic and connects to 51 healthcare banking partners, 44 clearinghouse partners, and 63 practice management systems via a library of 500+ configurable integrations.
MediStreams serves 750+ healthcare organizations and 350,000+ unique providers, processing 1.7B+ claims, 500M+ remittances, and $186B in payments annually. Named customers include Piedmont Healthcare (up to $50M daily payments across 26 hospitals), RadNet (16M+ claims automated across hundreds of imaging centers in 9 states), Luna Health, Aspen Dental, and Stance Health Solutions. The company sells through direct enterprise field sales complemented by channel partnerships with major banks (Regions, KeyBank, FNBO, JPMorgan Chase) and clearinghouses (Availity, with a decade-long partnership processing $61B in healthcare payments). Revenue is generated through subscription and per-transaction pricing across modules including Paper EOB Conversion, Rapid EOB Conversion, ERA Processing, Reconciliation, Medical Lockbox, Patient Payment Processing, and Correspondence.
MediStreams is a privately held LLC backed by TT Capital Partners following a 2021 growth equity investment. The leadership team remains founder-led (Jim Coyle as CEO, John Koch as COO, Joe Maher as President and CFO), with senior commercial and technology hires added in 2025 to support expansion. Compliance posture includes SOC 2 Type II (full-year 2025 unqualified opinion), HIPAA-aligned controls, AES-256 encryption, MFA, and a clean third-party penetration test. The company recently extended its platform with General Ledger Reconciliation (March 2026) and an AI-assisted Reconciliation Ledger (June 2026), positioning itself as the first end-to-end reconciliation provider spanning medical lockbox through financial reporting.
MediStream firmographics
Firmographics- Name
- MediStream
- Legal name
- MediStreams, LLC
- Website
- http://medistreams.com
- Company type
- Private
- Founded year
- 2009
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- MediStreams provides healthcare payment and remittance automation software that converts paper EOBs, electronic remittances, and lockbox payments into standardized posting files for health systems, ambulatory practices, DME suppliers, and channel partners. It serves 750+ clients and integrates with 51 banks and 44 clearinghouses.
- Ownership category
- akta.pro rank
MediStream industry classification
Industry- Product category
- Healthcare Revenue Cycle Management Software
- NAICS
- Computer Systems Design and Related Services (54151), Computer Systems Design and Related Services (5415), Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518)
- SIC
- Services-Prepackaged Software (7372), Services-Computer Programming, Data Processing, Etc. (7370)
- akta.pro primary industry
- Pharmacy Benefit Management (PBM) & Formulary Management IT (HLACAKAD)
- akta.pro secondary industry
- Healthcare Data Integration, ETL/ELT & Pipeline Orchestration (HLACAIAC)
Keywords
Where MediStream is headquartered
LocationHeadquarters
- HQ city
- Roswell
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
MediStream business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Healthcare Payment Automation Services: MediStreams generates revenue through automated healthcare payment processing services including EOB conversion, ERA processing, reconciliation, lockbox services, and correspondence indexing. The platform is sold as an outsourced service that integrates with clients' existing banking, clearinghouse, and practice management systems, typically with subscription-based or per-transaction pricing models.
- Transaction-Based Processing: Processing fees are charged per transaction for payment posting, reconciliation, and remittance conversion services. The platform delivers posting files configured to client specifications with 24-hour turnaround times.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Enterprise healthcare organizations - custom pricing based on transaction volume and service configuration |
| Transaction based/ take rate | Monthly | Per-transaction processing fees for payment posting and conversion services |
Go-to-market motion1 record
Distribution channels6 records
Marketing channels8 records
MediStream product offering
Product offeringCore offering
MediStreams operates the Cascade Product Suite, a healthcare payment and remittance automation platform that ingests paper EOBs, PDF remittances, lockbox mail, ERAs, EFTs, and patient payments from healthcare organizations and converts them into standardized, posting-ready outputs (ANSI 835 EDI files and journal-ready GL entries) for direct ingestion into practice management, EHR, and ERP systems. The platform combines medical lockbox services, paper EOB conversion, ERA processing, EFT-to-ERA reconciliation (including General Ledger Reconciliation), patient payment posting, and AI-powered correspondence indexing into a single end-to-end workflow backed by a library of 500+ configurable integrations to banks, clearinghouses, and PM/EHR systems.
Product overview
MediStreams offers the Cascade Product Suite, a comprehensive healthcare payment and remittance automation platform purpose-built for the complexity of healthcare reimbursement. The platform operates as a unified ecosystem of integrated modules rather than standalone tools: Paper EOB Conversion and Rapid EOB Conversion transform paper and PDF remittances into ANSI 835 EDI files; Medical Lockbox handles physical payment intake and digitization; ERA Processing consolidates electronic remittance advices; Reconciliation (including General Ledger Reconciliation) matches EFTs to ERAs and delivers funded posting files; Patient Payment Processing captures and posts patient payments; and Correspondence Indexing uses AI to classify and route payer correspondence. Together, these modules automate the full payment lifecycle from medical lockbox through EHR posting to financial reporting, connecting with 51 healthcare banking partners, 44 clearinghouse partners, and 63 practice management systems.
Differentiator
Problem solved
Functional benefit
Brands
- Cascade Product Suite: The company's product platform for healthcare payment and remittance automation, including EOB conversion, ERA processing, reconciliation, medical lockbox, and correspondence services.
Products and services
- Cascade Product Suite Overarching healthcare payment and remittance automation platform encompassing all product modules including Paper EOB Conversion, Medical Lockbox, ERA Processing, Reconciliation, Patient Payment Processing, and Correspondence. Provides end-to-end automation from medical lockbox through EHR posting to financial reporting, built for hospital systems, ambulatory practices, DME suppliers, and partner banks/clearinghouses.
- Paper EOB Conversion Converts paper Explanation of Benefits (EOB) and check images into ANSI 835 EDI posting files configured for the provider's practice management or hospital information system. Delivers output within 24 hours with 96% accuracy rate, and includes a 10-year web portal archive and a 500+ library of reusable configurations. For healthcare providers, RCM teams, and billing operations that receive paper remittances from payers.
- Rapid EOB Conversion Rapid-response solution for backlog payment processing, particularly for providers affected by the Change Healthcare cyberattack. Converts PDF EOBs to ANSI 835 files via SFTP upload with minimal manual intervention, and includes a web portal for denial identification, secondary billing information, and 10-year image retention. For healthcare providers needing fast turnaround on remittance backlogs.
- ERA Processing Loads, processes, and archives electronic remittance advices (ERAs) with normalization across payers. Consolidates all remittances in one web portal location with consistent human-readable layouts, and supports file splitting for delivery to multiple systems plus download, printing, and searching. For healthcare providers and RCM teams managing high volumes of electronic remittances from multiple payers.
- Reconciliation Automated matching of EFTs to ERAs to deliver funded ANSI 835 posting files only when bank deposits are confirmed, with continuous 24/7 processing. Includes analytics for pending and reconciled remittances, unmatched EFT/ERA queues, and identification of under/over/posted remittances. Now includes General Ledger Reconciliation that generates journal-ready outputs to ERP and general ledger systems. For healthcare finance and revenue cycle teams that need to close books faster and trace every payment.
- Patient Payment Processing Captures patient payment information from checks, coupons, or statements and delivers configured posting files within 24 hours to accounts receivable software. All images and data are available in a HIPAA-compliant web portal for 10 years. For healthcare providers processing patient payments alongside payer remittances.
- Medical Lockbox Bank-agnostic medical lockbox for healthcare that deposits to any bank and streamlines collection of paper payments and correspondence. Eliminates the opening, sorting, and processing of incoming mail, transitioning from paper to digital, and provides daily reports including deposit totals and transaction details. For health systems and multi-site provider organizations receiving paper-based payer and patient payments.
- Correspondence (Indexed Correspondence) AI-powered automation for indexing and routing payer correspondence including denials, audits, and fee schedule changes. Uses OCR and NLP to categorize more than 30 document types with 99% accuracy and a 24-hour SLA. Delivers indexed files to Epic, Cerner/Oracle Health, OnBase, and other EHR/document management systems with a 10-year searchable archive. For healthcare revenue cycle teams that need to triage large volumes of payer correspondence.
Companies that use MediStream
Customer profileNamed customers7 records
Segments7 records
Ideal customer profiles4 records
MediStream technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration11 records
AI capability8 records
Feature6 records
MediStream partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered key strategic and strategic.
- FNBO (First National Bank of Omaha)key strategicStrategic solution agreement to enhance FNBO's healthcare banking offerings with advanced payment automation and reconciliation capabilities. FNBO will offer MediStreams technology to healthcare clients combining financial services expertise with automation technology.
- Regions Bankkey strategicRegions Bank launched enhanced Treasury Management services for healthcare clients powered by MediStreams technology. Services include automated payment processing, remittance, and reconciliation workflows targeting major health systems, physician groups, clinics, labs, and pharmacies.
- KeyBankkey strategicKeyBank selected MediStreams as technology partner for bank's new healthcare payment management platform. Combined KeyBank lockbox technology with MediStreams automated posting and reconciliation capabilities for integrated healthcare client experience.
- AvailitystrategicDecade-long partnership with Availity automating $61B in healthcare payments for healthcare clients. Partnership helps deliver scale, speed, and accuracy for thousands of providers.
- JPMorgan Chasekey strategicBanking partner integrated with MediStreams platform for healthcare clients including RadNet. Part of 51 healthcare banking partners ecosystem.
- Epickey strategicMajor EHR system integrated with MediStreams for correspondence delivery and payment posting workflows.
- Cerner (Oracle Health)key strategicMajor EHR system integrated with MediStreams for correspondence delivery and payment posting workflows.
Scale indicators18 records
Recent moves7 records
Expansion highlights6 records
MediStream competitors and assessment
Company assessmentDirect peers
- Waystar: Direct competitor offering a healthcare revenue cycle and payment automation platform that includes remittance processing, ERA/EOB workflows, and reconciliation for providers and health systems — directly overlapping MediStreams' core lockbox → posting → reconciliation workflow.
- Availity: Large healthcare clearinghouse partner that also offers remittance and payment automation to providers; MediStreams' decade-long partnership (processing $61B) and overlapping capabilities make Availity both an ally and a direct competitor in payment posting.
- InstaMed (JPMorgan Chase): A JPMorgan-owned healthcare payments network that processes medical payments end-to-end; serves many of the same provider and payer segments as MediStreams with overlapping remittance/reconciliation capabilities.
- Quadax: Specialized healthcare RCM and remittance automation vendor serving labs, hospitals, and physician groups with overlapping ERA/EOB processing and payment reconciliation capabilities similar to MediStreams' Cascade Suite.
- Navicure / ZirMed (Waystar legacy): Now part of Waystar, Navicure/ZirMed historically offered payer-provider claim and remittance management for ambulatory and hospital markets, mirroring MediStreams' provider-facing payment automation.
Broad incumbents
- Experian Health: A larger healthcare technology vendor offering claims management, payment processing, and revenue cycle automation; provides overlapping remittance automation services with broader eligibility and identity management capabilities.
- Change Healthcare (Optum/UnitedHealth): Historically dominant healthcare clearinghouse and payment network that processed remittance flows for tens of thousands of providers; the 2024 cyberattack reshuffled the market, but Optum's broader RCM and payment capabilities overlap with MediStreams' automated remittance and reconciliation offerings.
- Trizetto (Cognizant): Long-standing healthcare claims processing and revenue cycle management platform competing in the payer-provider payment and remittance category as part of broader IT services from Cognizant.
Others
- Health Catalyst: Healthcare data and analytics platform with overlapping healthcare IT vendor relationships; while more analytics-focused, it serves many of the same health-system finance and revenue cycle buyers as MediStreams.
Emerging players
- HealthPayIQ (Apex Health): A focused healthcare payment automation and analytics vendor serving providers and TPAs with remittance and reconciliation offerings that overlap MediStreams' processing modules.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
MediStream social profiles
Digital presenceMediStream compliance and trust
Trust signalCompliance3 records
MediStream financial estimates
Financial estimateRevenue estimate
Valuation estimate
MediStream leadership team
Management profileNumber of profiles
Profiles4 records
MediStream subsidiaries and ownership
Company hierarchySubsidiaries1 record
MediStream funding detail
Funding detailFunding overview
Funding rounds2 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
MediStream M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about MediStream
What does MediStream do?
MediStreams operates the Cascade Product Suite, a healthcare payment and remittance automation platform that ingests paper EOBs, PDF remittances, lockbox mail, ERAs, EFTs, and patient payments from healthcare organizations and converts them into standardized, posting-ready outputs (ANSI 835 EDI files and journal-ready GL entries) for direct ingestion into practice management, EHR, and ERP systems. The platform combines medical lockbox services, paper EOB conversion, ERA processing, EFT-to-ERA reconciliation (including General Ledger Reconciliation), patient payment posting, and AI-powered correspondence indexing into a single end-to-end workflow backed by a library of 500+ configurable integrations to banks, clearinghouses, and PM/EHR systems.
Is MediStream a public or private company?
MediStream is a private company. It is classified as private equity controlled and is currently operating.
When was MediStream founded?
MediStream was founded in 2009. It employs 11 to 50 people.
Where is MediStream based?
MediStream is headquartered in Roswell, United States, in the North America region.
How does MediStream make money?
Two revenue lines are on record. Healthcare Payment Automation Services are the primary driver. The others are transaction-Based Processing.
Who are MediStream's main competitors?
Direct peers on record are Waystar, Availity, InstaMed (JPMorgan Chase), Quadax and Navicure / ZirMed (Waystar legacy). Broad incumbents are Experian Health, Change Healthcare (Optum/UnitedHealth) and Trizetto (Cognizant). Health Catalyst is listed as an others. HealthPayIQ (Apex Health) is listed as an emerging player.
Does MediStream have an API?
No public API is recorded for MediStream.
What industry is MediStream in?
MediStream's product category is Healthcare Revenue Cycle Management Software. Its primary akta.pro industry code is HLACAKAD, Pharmacy Benefit Management (PBM) & Formulary Management IT, with a secondary code of HLACAIAC, Healthcare Data Integration, ETL/ELT & Pipeline Orchestration. Its NAICS code is 54151 and its SIC code is 7372.