Clinical Research Billing
Clinical Research Billing is a US-based outsourced billing services firm that manages CTMS billing, reconciliation, and accounts receivable for clinical research sites and site networks on a performance-based, percentage-of-receipts pricing model.
- Company typePrivate
- Founded2015
- HeadquartersLake Worth, United States
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Clinical Research Billing does
Clinical Research Billing (CRB) is a US-based, privately held outsourced billing services firm founded in 2015 and headquartered in Lake Worth, Florida. The company specializes in end-to-end revenue cycle management for clinical research sites and site networks, covering budget review and negotiation, CTMS implementation and management, invoice generation, payment reconciliation, extra-procedure tracking, and active accounts receivable follow-up. Its stated purpose is to allow clinical and administrative site staff to remain focused on research while CRB ensures no payable visit, procedure, or contractual item is lost or under-collected.
CRB's core technology is a CTMS-anchored billing and reconciliation platform that integrates with the four dominant clinical trial management systems used by independent sites and large networks: RealTime, CRIO, Clinical Conductor, and eClinPro. Through these integrations, CRB produces monthly financial reports on accounts receivable, payments, and revenue, supports both accrual- and cash-basis accounting, and identifies extra invoiceable items that can represent 10-50% of total study revenue depending on therapeutic area. The company also provides on-site financial reviews, valuation and due diligence support for site sales, and accounting-software integration. All services are delivered remotely by a team of 30+ Account Managers and Account Supporters under the leadership of a management team with 50+ years of combined industry experience across research sites, SMOs, CROs, and software development.
CRB operates a performance-based revenue model, charging a percentage of client gross receipts with no upfront or fixed fees, which the company uses to align its incentives with site cash collection. It serves two primary customer segments: independent research sites requiring dedicated billing support, and large institutions and networks that operate across multiple CTMS platforms and require cross-site financial oversight and acquisition integration support. GTM is sales-led through consultation scheduling on the website and reinforced by an active conference presence at SCRS, Site Council, CRIO Connect Live, Save Our Sites, SCRS West, and ASN Kidney Week, complemented by content marketing, podcast appearances, and a formal partnership with CRIO.
Clinical Research Billing firmographics
Firmographics- Name
- Clinical Research Billing
- Legal name
- Clinical Research Billing
- Website
- https://clinicalresearchbilling.com
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Clinical Research Billing is a US-based outsourced billing services firm that manages CTMS billing, reconciliation, and accounts receivable for clinical research sites and site networks on a performance-based, percentage-of-receipts pricing model.
- Ownership category
- akta.pro rank
Clinical Research Billing industry classification
Industry- Product category
- Clinical Research Billing Services
- NAICS
- Scientific Research and Development Services (5417)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Clinical Trial Financial Management & Payments (Site Budgeting) (HLAGACAM)
- akta.pro secondary industries
- Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Clinical CROs (Phase I–IV) (HLAGAAAA)
Keywords
Where Clinical Research Billing is headquartered
LocationHeadquarters
- HQ city
- Lake Worth
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Clinical Research Billing business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D, Others
Revenue model
- Performance-Based Billing Service: Charges a percentage of gross receipts with no upfront or fixed costs. Success-based model where CRB gets paid only when the client gets paid. This aligns interests and ensures revenue capture for clinical research sites.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Transaction based/ take rate | Pay-as-you-go | Percentage of gross receipts - performance-based pricing with no upfront fees |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels6 records
Clinical Research Billing product offering
Product offeringCore offering
Clinical Research Billing (CRB) provides outsourced end-to-end research billing services for clinical research sites and site networks. The service integrates with the client's Clinical Trial Management System (RealTime, CRIO, Clinical Conductor, eClinPro) to manage visit payments, extra procedures, invoice generation, payment reconciliation, and accounts receivable follow-up. Revenue is earned on a performance-based model as a percentage of gross receipts with no upfront or fixed costs.
Product overview
Clinical Research Billing offers a unified billing service platform for clinical research sites and site networks, combining multiple service modules into a single outsourced solution. The core offering integrates with the site's CTMS (RealTime, CRIO, Clinical Conductor, eClinPro) to manage visit payments, extra procedures, billing, and payment reconciliation from budget negotiations through cash collection. Key service modules include: Extra Procedures Tracking (for items representing 10-50% of study revenue), Invoicing and Accounts Receivable Management, Financial Reviews and Valuation Support, CTMS/eSource Setup, and Accounting Integration. CRB operates on a performance-based pricing model (percentage of gross receipts with no upfront costs), serving both independent research sites and large institution networks.
Differentiator
Problem solved
Functional benefit
Products and services
- Research Billing Services End-to-end revenue management for clinical research sites and site networks, including budget review and negotiation support, invoice generation and submission, payment reconciliation, active accounts receivable follow-up, and CTMS/eSource setup support using the client's CTMS (RealTime, CRIO, Clinical Conductor, eClinPro). Designed for independent research sites and large site networks that need dedicated billing capacity.
Quantifiable outcome
- Extra invoiceable items represent 10-50% of total study revenue depending on therapeutic area - recoverable through systematic tracking
- +1 more outcomes
Companies that use Clinical Research Billing
Customer profileNamed customers2 records
Segments2 records
Ideal customer profiles2 records
Clinical Research Billing technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration4 records
Feature3 records
Clinical Research Billing partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core and minor.
- CRIOcoreCRIO is a Clinical Trial Management System platform that CRB implements and manages. CRB has a formal partnership with CRIO including a case study highlighting collaboration to help clinical research organizations identify missed billables, improve financial records, and increase site valuation. CRB led a featured session at CRIO Partner Expo 2025 and provides CRIO-informed best practices for sponsor reimbursement achieving 75-100% rates.
- RealTime CTMScoreCRB implements and manages RealTime CTMS for clinical research sites as part of their billing service offering.
- Clinical ConductorcoreCRB implements and manages Clinical Conductor CTMS for clinical research sites as part of their billing service offering.
- eClinProcoreCRB implements and manages eClinPro CTMS for clinical research sites as part of their billing service offering.
- Site CouncilminorCRB actively participates in Site Council Leadership Forum events. Site Council brings together site leaders, study sponsors, and CROs to engage constructively on industry problems.
- SCRS (Society for Clinical Research Sites)minorCRB is an active presence at SCRS Global Site Solutions Summit and SCRS West events. SCRS is an international summit connecting clinical research site leaders and solution partners.
- Save Our Sites (SOS)minorCRB participated in SOS Round Table video session discussing how CRB works to Save Our Sites. SOS is an annual conference bringing together research sites to discuss sustainability, operations, and industry challenges.
Scale indicators3 records
Recent moves5 records
Expansion highlights4 records
Clinical Research Billing competitors and assessment
Company assessmentDirect peers
- CRIO: CRIO is a leading CTMS platform for clinical research sites. CRB both implements/manages CRIO for clients and has a formal partnership with CRIO including a co-published case study and featured Partner Expo session, making it a core technology partner and direct overlap in site workflows.
- RealTime CTMS (Anju Software): RealTime is one of the four CTMS platforms CRB implements and manages. Both companies compete for the same site customer's budget — RealTime as the system of record and CRB as the outsourced financial workflow layer on top of it.
- Bio-Optronics: Bio-Optronics sells Clinical Conductor CTMS, one of the platforms CRB implements and manages. Both compete for site technology spend, with Bio-Optronics owning the system and CRB offering the outsourced financial service layer on top.
Broad incumbents
- Advarra: Advarra provides a broad portfolio of clinical research services to sites and sponsors, including IRB, technology, and site enablement. It overlaps with CRB in serving site operational and financial workflow needs at a larger scale and broader scope.
- WCG (WIRB-Copernicus Group): WCG is a large incumbent clinical research services company offering IRB, technology, and site/sponsor solutions. Its Clinical Research Solutions portfolio competes with CRB for site-level operational and financial workflow spend, though at a much broader scope.
- Veeva Systems: Veeva offers a broad clinical trial technology suite (CTMS, eTMF, CDB) used by sponsors, CROs, and increasingly sites. While Veeva serves a larger buyer set, its CTMS offering competes with the workflow layer where CRB operates.
- Medidata (Dassault Systèmes): Medidata provides a comprehensive clinical trial technology platform spanning EDC, CTMS, eCOA, and analytics. While primarily sponsor/CRO-focused, its site-facing modules overlap with the workflows CRB monetizes.
- Clario: Clario (formerly ERT) delivers clinical trial technology and endpoint services to sponsors and sites. Its site technology offerings intersect with the workflow and financial management space where CRB operates.
- Anju Software: Anju Software is a clinical trial software suite provider including CTMS, eTMF, and IWRS. Its site-facing modules and RealTime CTMS brand overlap directly with the platforms CRB supports and the site workflow spend CRB competes for.
Emerging players
- Florence Healthcare: Florence Healthcare provides site connectivity and document/workflow tooling for clinical research sites. It is an emerging player addressing adjacent site pain points (eSource, document exchange) and competes for the same site's overall technology/workflow budget.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Clinical Research Billing social profiles
Digital presenceClinical Research Billing financial estimates
Financial estimateRevenue estimate
Valuation estimate
Clinical Research Billing leadership team
Management profileNumber of profiles
Profiles7 records
Clinical Research Billing funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Clinical Research Billing M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Clinical Research Billing
What does Clinical Research Billing do?
Clinical Research Billing (CRB) provides outsourced end-to-end research billing services for clinical research sites and site networks. The service integrates with the client's Clinical Trial Management System (RealTime, CRIO, Clinical Conductor, eClinPro) to manage visit payments, extra procedures, invoice generation, payment reconciliation, and accounts receivable follow-up. Revenue is earned on a performance-based model as a percentage of gross receipts with no upfront or fixed costs.
Is Clinical Research Billing a public or private company?
Clinical Research Billing is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Clinical Research Billing founded?
Clinical Research Billing was founded in 2015. It employs 11 to 50 people.
Where is Clinical Research Billing based?
Clinical Research Billing is headquartered in Lake Worth, United States, in the North America region.
How does Clinical Research Billing make money?
One revenue line is on record: performance-Based Billing Service.
Who are Clinical Research Billing's main competitors?
Direct peers on record are CRIO, RealTime CTMS (Anju Software) and Bio-Optronics. Broad incumbents are Advarra, WCG (WIRB-Copernicus Group), Veeva Systems, Medidata (Dassault Systèmes), Clario and Anju Software. Florence Healthcare is listed as an emerging player.
Does Clinical Research Billing have an API?
No public API is recorded for Clinical Research Billing.
What industry is Clinical Research Billing in?
Clinical Research Billing's product category is Clinical Research Billing Services. Its primary akta.pro industry code is HLAGACAM, Clinical Trial Financial Management & Payments (Site Budgeting), with a secondary code of HLAGAAAI, Patient Recruitment, Site Feasibility & Trial Enablement CROs. Its NAICS code is 5417 and its SIC code is 8731.