Researched Nutritionals

What Researched Nutritionals does

Researched Nutritionals is a private, practitioner-exclusive nutritional supplement company founded in 2006 and headquartered in Los Olivos, California. The company develops and sells professional-grade dietary supplement formulations targeting specific clinical mechanisms — mitochondrial energy production (ATP 360®, ATP Fuel®), intracellular antioxidant defense (Tri-Fortify® liposomal glutathione, C-RLA™), immune modulation (Transfer Factor Multi-Immune™, Transfer Factor Rapid Response™), cytokine balance (CytoQuel®), cognitive function (BDNF Essentials®, CogniCare®), gut barrier integrity (RenewGut™, RenewGut Thrive™), microbial biofilm disruption (BioDisrupt®), and mast cell/histamine response (HistaQuel®). Its technical differentiation rests on proprietary branded ingredient blends (Membrane Potential™, Krebs Plus Foundation™, Bioisolate™, Mast Cell Secure™), liposomal phospholipid delivery systems for actives with poor oral bioavailability, and a notably deep clinical evidence base — multiple peer-reviewed human clinical studies on its own formulations, published between 2018 and 2024 in journals including the European Journal of Clinical Nutrition, Journal of Pain Research, and Current Nutraceuticals.

The company operates a sales-led GTM through a practitioner-exclusive direct channel. Healthcare professionals (MDs, DCs, NDs, acupuncturists, dentists, nurse practitioners, clinical nutritionists, and pharmacists) must register, verify their professional license, and receive account approval before they can view pricing or purchase. Approved practitioners can dispense or recommend products to patients and enable Patient Direct Ordering, allowing their patient base to reorder directly through the company's e-commerce site under practitioner authorization. Revenue is generated through one-time purchases supplemented by subscription/automatic refill programs with free-shipping incentives. The company does not disclose pricing publicly and does not use retail or consumer-direct channels, instead investing in clinical credibility, educational content (Solutions for Life blog), and webinar-based thought leadership partnerships — including a collaboration with the Personalized Lifestyle Medicine Institute (PLMI) led by Dr. Jeffrey Bland.

Researched Nutritionals is structured as Researched Nutritionals, LLC, with no disclosed parent company, venture capital backing, or external investment, and is led by founder and CEO Dennis Schoen. The company maintains an A+ BBB rating, operates with 11-50 employees, and holds multiple registered trademarks for its branded formulations. Geographic operations are US-domestic, with the United Kingdom explicitly excluded from shipping. The principal strategic pillars observable from the data are: (1) deepening the evidence-based moat through ongoing clinical publishing, (2) increasing per-practice revenue through bundled protocols and category breadth, and (3) reinforcing channel control through practitioner education partnerships rather than consumer marketing.

Name

Researched Nutritionals

Legal name

Researched Nutritionals, LLC

Website

https://researchednutritionals.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

11–50 employees

Short description

Researched Nutritionals is a practitioner-exclusive nutritional supplement company founded in 2006, serving licensed healthcare professionals with proprietary, peer-reviewed-validated formulations targeting mitochondrial function, immune modulation, cognitive health, and gut-brain-immune axis support.

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Food (Health) Supplement Retailers (456191), Health and Personal Care Retailers (456)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Specialty Condition Supplements (Sleep, Stress, Heart, Joint, Gut, Immunity) (CRADAGAE)

akta.pro secondary industry

Healthy Aging & Cognitive Support Supplements (CRADAGAM)

Keywords

• Practitioner-grade supplements
• Liposomal glutathione formulas
• Mitochondrial support supplements
• Immune transfer factor blends
• Clinical-grade nutraceuticals

Headquarters

HQ city

Los Olivos

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Professional-grade dietary supplement sales: The company generates revenue through direct sales of practitioner-exclusive nutritional supplement products. Products are sold primarily to licensed healthcare professionals (MDs, DCs, NDs, etc.) who then recommend or dispense them to patients. Practitioners can also enable Patient Direct Ordering, allowing patients to purchase directly through the website under practitioner authorization.
2. Subscription / Automatic Refill Orders: Researched Nutritionals offers subscription/auto-refill programs for ongoing product orders. Customers can set up recurring deliveries with subscription plans, and the company offers free shipping on subscription orders as a demand-generation and retention lever.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels3 records

Core offering

Researched Nutritionals manufactures and sells practitioner-exclusive dietary supplement formulations targeting mitochondrial function, immune support, detoxification, cytokine modulation, gut-brain axis, cognitive health, and stress response. Products are sold directly to licensed healthcare professionals (MDs, DCs, NDs, etc.) who dispense or recommend them to patients, with practitioners also able to enable Patient Direct Ordering for end users. The portfolio spans 16 health categories and includes clinically researched flagship lines such as ATP 360®, Tri-Fortify®, Transfer Factor Multi-Immune™, BioDisrupt®, CytoQuel®, and BDNF Essentials®.

Product overview

Researched Nutritionals is a practitioner-exclusive nutritional supplement brand offering a comprehensive portfolio of research-backed formulas targeting key areas of health including mitochondrial function, immune support, detoxification, cytokine health, gut health, cognition, and stress management. The product line centers on clinically researched flagship products including ATP 360® (mitochondrial support), Tri-Fortify® (liposomal glutathione), Transfer Factor Multi-Immune™ (immune support), BioDisrupt® (microbial biofilm support), CytoQuel® (cytokine support), and BDNF Essentials® (neuroplasticity support). These core products are complemented by product bundles such as the Vagal Nerve Vitality Bundle (combining ATP 360®, BDNF Essentials®, and RenewGut Thrive™) and Daily Essentials collection for foundational wellness support. Additional offerings span antioxidants, probiotics, minerals, omega-3s, sleep support, mast cell support, oral health, mycotoxin detoxification, coagulation support, and joint/soft tissue products. The company differentiates through published peer-reviewed clinical research on their formulations and a practitioner-exclusive distribution model requiring professional license verification for purchase.

Differentiator

Problem solved

Functional benefit

Products and services

• ATP 360® Comprehensive mitochondrial support formula designed to optimize mitochondrial function, supporting and protecting mitochondrial membranes with targeted phospholipids, Krebs cycle cofactors, and mitochondrial biogenesis support; intended for practitioners managing patients with energy and mitochondrial dysfunction concerns.
• Tri-Fortify® Clinically researched oral liposomal glutathione supplement with proven intracellular absorption, available in Orange and Watermelon formulations; intended for practitioners addressing oxidative stress, detoxification support, and glutathione elevation in patients.
• Transfer Factor Multi-Immune™ Advanced immune support formula comprising proprietary blend of bovine-derived transfer factors, whole colostrum, immune-supporting herbs, and mushrooms supporting NK cell function and immune modulation; intended for practitioners treating immune dysregulation in patients.
• BioDisrupt® Clinically researched formula featuring EnzymeDisrupt™ and HerbDisrupt™ proprietary blends for comprehensive microbial biofilm support by disrupting biofilm matrix and inhibiting new biofilm formation; intended for practitioners managing microbial balance and biofilm-related patient concerns.
• CytoQuel® Comprehensive blend to promote healthy cytokine function, backed by peer-reviewed research published in the Journal of Pain Research; intended for practitioners managing chronic inflammation and cytokine balance in patients.
• BDNF Essentials® Clinically researched comprehensive formula designed to support neurological health and cognitive function by aiding the formation of nerve growth factors such as BDNF; intended for practitioners treating cognitive decline and neuroplasticity concerns.
• Vagal Nerve Vitality Bundle Bundle combining ATP 360®, BDNF Essentials®, and RenewGut Thrive™ to address healthy autonomic nervous system response (vagal tone) and mitochondrial resilience.
• Transfer Factor Rapid Response™ Next-generation immune support formula delivering fast-acting, multi-mechanism approach with most potent Transfer Factor blend, promoting both innate and adaptive immune functions.
• Lumbrokinase High-potency (880,000 IU/serving) delayed-release lumbrokinase enzyme to support circulatory health and promote balanced coagulation and fibrinolysis.
• RenewGut Thrive™ 3-in-1 formula featuring pasteurized Akkermansia supporting gut-brain-immune axis by promoting gut barrier integrity, microbiome balance, and healthy immune modulation.
• AnxiaEase™ Stress and mood support formula featuring adaptogenic herbs, calming nutrients, and psychobiotic probiotic strains targeting the gut-brain axis.
• Physician's Daily™ Multivitamin + D3 Comprehensive daily multivitamin formula providing foundational nutritional support with added vitamin D3.
• Magnesium Glycinate Bioavailable magnesium supplement (250mg per serving) in highly absorbable glycinate form, less likely to cause loose stools.
• CoQ10 Power™ Coenzyme Q10 supplement (400mg softgel) for mitochondrial energy production and cardiovascular support.
• Omega-3 Plus™ Double-strength omega-3 fatty acid soft gels providing foundational fatty acid support.
• CoreBiotic® Soil-based probiotic formula supporting gut health and microbiome balance.
• CoreBiotic® Sensitive Sensitive-formula probiotic variant for individuals with sensitivities requiring specialized probiotic support.
• Core Minerals™ Balanced multi-mineral complex providing twelve minerals plus vitamin D3 in easily assimilated forms, iron-free formulation.
• Multi-Biome™ Extra-strength probiotic formula providing broad-spectrum microbiome support.
• Ubiquinol Super 200™ Reduced form of CoQ10 (ubiquinol) supplement supporting mitochondrial function and cellular energy production.
• C-RLA™ Original High-dose liposomal vitamin C (1500mg) and R-lipoic acid (70mg) in natural, non-GMO liposomal preparation using sunflower-derived phospholipids.
• C-RLA™ Vanilla Caramel Liposomal vitamin C variant with vanilla caramel flavor, providing 1500mg vitamin C and 70mg R-lipoic acid.
• H2 Absorb™ Molecular hydrogen water supplement for antioxidant support.
• TocoPure™ D&G Tocotrienol supplement providing delta and gamma tocotrienol forms of vitamin E for antioxidant support.
• ATP Fuel® Optimized energy formula promoting healthy mitochondrial membrane function and maximizing Krebs cycle cellular energy production.
• Energy Multi-Plex™ Comprehensive adrenal support formula for energy metabolism and stress response.
• Optimized Energy Duo™ Bundle combining products for optimized cellular energy production and mitochondrial function.
• RibosCardio™ D-ribose supplement with Cardioperform for cardiovascular energy support.
• Cognitive Performance Duo™ Bundle of cognitive support formulas for enhanced mental performance.
• CogniCare® Cognitive performance supplement supporting memory, focus, and mental clarity.
• Curcumin Pure™ Pure CurcuWin™ turmeric extract (500mg per serving) with 46x better absorption than standard curcumin using UltraSOL™ technology.
• InflaQuell™ Proteolytic enzyme supplement for inflammatory response support.
• Artemisinin SOD™ Pure artemisinin combined with green tea extract for immune support and healthy SOD (superoxide dismutase) levels.
• Artemisinin Solo™ Standalone pure artemisinin product for immune support.
• Enhanced Immunity Duo™ Bundle combining immune support formulas for enhanced immune function.
• Transfer Factor Sensitive™ Transfer factor variant designed for sensitive individuals requiring gentle immune support.
• RenewGut™ Gut health formula supporting gut barrier integrity and microbiome balance.
• OraMax™ Oral health solution in dissolvable tablet form with probiotics, enzymes, nutrients, and herbs supporting healthy oral microbiome.
• MycoPul® Mycotoxin binder using multiple targeted ingredients including G-PUR® Zeolite and PureBind™ humic acid for mycotoxin removal from GI tract.
• PectaSol-C® Modified citrus pectin supplement for detoxification support, available in capsule and powder forms.
• HistaQuel® Comprehensive mast cell support formula with flavonoids and herbs promoting healthy mast cell function and histamine response.
• Soothe & Relaxx™ Joint and soft tissue support supplement for musculoskeletal comfort.
• Circadian PM™ Sleep support formula with neurotransmitter, cytokine, and histamine support utilizing PharmaGABA® and 10 ingredients for complete sleep management.
• Boluoke® Lumbrokinase Alternative lumbrokinase product available in 60 and 120 capsule sizes for circulatory support.

Quantifiable outcome

• 28% increase in intracellular glutathione levels after 2 weeks of Tri-Fortify® use (Penn State University human study)
• +4 more outcomes

Named customers1 record

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature11 records

Partnerships

One partnership is on record.

• Personalized Lifestyle Medicine Institute (PLMI)minorGTM or Marketing PartnerResearched Nutritionals partnered with the Personalized Lifestyle Medicine Institute (PLMI), headed by Dr. Jeffrey Bland, to host educational webinars in functional and personalized lifestyle medicine. An example is the webinar 'Mitochondria Through the Lense of the Gut-Heart-Brain Axis' featuring Dr. Jeffrey Bland, Dr. Sanjay Bhojraj, and Dr. Lisa Portera. The partnership provides practitioners free 30-day trial memberships to PLMI and promotes educational content as a GTM lever.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Pure Encapsulations: Pure Encapsulations is one of the largest practitioner-exclusive supplement brands in the US, sold through licensed healthcare professionals. Like Researched Nutritionals, it emphasizes purity, third-party testing, and clinical-quality formulations targeting functional and integrative medicine practitioners.
• Designs for Health: Designs for Health is a practitioner-exclusive nutritional supplement company offering branded, clinically researched formulations to licensed healthcare providers. Its direct-to-practitioner sales model and emphasis on condition-specific product lines (metabolic, immune, cognitive) closely mirror Researched Nutritionals' positioning.
• Xymogen: Xymogen is a practitioner-only nutritional supplement brand distributing exclusive formulas to licensed healthcare professionals. It shares Researched Nutritionals' evidence-based, condition-targeted approach and gated B2B sales model.
• Integrative Therapeutics: Integrative Therapeutics is a practitioner-grade supplement brand owned by Standard Process, focused on clinical and integrative medicine practitioners. Its product breadth across immune, gut, mitochondrial, and cognitive categories parallels Researched Nutritionals' portfolio.
• Biotics Research: Biotics Research is a practitioner-only nutritional supplement manufacturer with a focus on whole-food and glandular-based formulations, serving DCs, NDs, and integrative MDs. Its practitioner-exclusive GTM and emphasis on quality assurance overlap directly with Researched Nutritionals.
• Apex Energetics: Apex Energetics is a practitioner-exclusive supplement company specializing in condition-specific formulations for functional medicine practitioners, with an emphasis on clinical testing and practitioner education. Its niche, evidence-focused positioning is closely aligned with Researched Nutritionals.

Broad incumbents

• Metagenics: Metagenics is a large, established practitioner-exclusive supplement and medical foods company with broad product lines, clinical research programs, and a global footprint. It competes across multiple categories where Researched Nutritionals operates (mitochondrial, immune, gut) but at significantly greater scale.
• Thorne: Thorne is a premium supplement company with both practitioner and consumer channels, known for NSF Certified for Sport products and peer-reviewed research. While it has broader distribution (DTC, Amazon, retail), it competes directly in mitochondrial, cognitive, and immune categories where Researched Nutritionals operates.
• Douglas Laboratories: Douglas Laboratories is a long-established practitioner-grade supplement brand serving healthcare professionals with a broad portfolio of vitamins, minerals, and condition-specific formulations. It competes in overlapping categories (cognitive, immune, mitochondrial) under a similar B2B-practitioner model.
• Standard Process: Standard Process is a whole-food supplement manufacturer distributing through healthcare practitioners, with a vertically integrated farm-to-capsule supply chain. While it has a different formulation philosophy (whole-food vs. isolated nutrients), it competes in the same practitioner-exclusive channel.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/rnutritionals
• Facebookfacebook.com/ResearchedNutritionals
• LinkedInlinkedin.com/company/researched-nutritionals-llc

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Researched Nutritionals