What Apex Energetics does

Apex Energetics, Inc. is a privately held professional dietary supplement company headquartered in Irvine, California, that develops and distributes research-guided nutritional formulas exclusively through licensed healthcare professionals. Operating for over 30 years, the company integrates functional medicine, chiropractic principles, Eastern medicine, and nutritional science into a portfolio spanning 12+ physiological support categories including blood sugar, brain, cardiovascular, endocrine, gastrointestinal, hepatobiliary, immune, musculoskeletal, urinary, and stress-related systems.

The company's technology stack centers on proprietary formulations combining phytonutrients, cofactors, enzymes, amino acids, and botanicals. Notable technical components include GG-Gold™ geranylgeraniol (licensed from American River Nutrition under US Patents 7,989,006 and 8,293,290) used in mitochondrial-targeting formulas, a proprietary liposomal delivery platform (C Liquazome™) for vitamin C and glutathione bioavailability via SVCT1 receptors and liposomal structures, broad-spectrum enzyme blends in the TerrainZyme™ line, and acid-resistant vegetarian capsules designed for intestinal delivery of S-acetyl L-glutathione. Three branded product lines anchor the portfolio: K-Line Nutritionals™ (organized by physiological system), TerrainZyme™ Z-Plex (plant enzyme-based formulas for biological terrain), and Herbal H-Plex (European plant bud extracts for organ drainage and detoxification).

Apex Energetics generates revenue through a strictly gated B2B distribution model in which products are sold only to approved healthcare professional accounts who then dispense to patients under their direct care. Distribution occurs through three channels: in-office dispensing, practitioner-owned registered websites, and certain in-office-only products. Third-party marketplaces (Amazon, eBay) are prohibited, and pricing is not publicly disclosed. A Scientific Advisory Board of five named clinicians/researchers provides product development expertise, clinical protocols, and brand validation. The company is cGMP-compliant with quality standards described as exceeding industry requirements, holds IFOS and GOED certifications on certain omega-3 products, and accepts international shipments (with import-compliance disclaimers).

Name

Apex Energetics

Legal name

Apex Energetics, Inc.

Website

https://apexenergetics.com

Company type

Private

Founded year

1987

Operating status

Operating

Headcount range

101–250 employees

Short description

Apex Energetics is a California-based, privately held professional dietary supplement company that develops and distributes over 50 research-guided nutritional products across 12 physiological categories exclusively through approved healthcare professionals (functional medicine practitioners, chiropractors, naturopaths) in the U.S. and internationally.

Ownership category

akta.pro rank

Product category

Professional Dietary Supplements

NAICS

Drugs and Druggists' Sundries Merchant Wholesalers (4242)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Healthy Aging & Cognitive Support Supplements (CRADAGAM)

akta.pro secondary industries

Weight Management & Metabolic Supplements (CRADAGAG), Probiotics & Digestive Health Supplements (CRADAGAF), Amino Acids & Peptides (BCAAs, Collagen Peptides, Bioactive Peptides, L-Theanine) (AFAJAKAG), Fats, Oils & Lipid Ingredients (Specialty Oils, MCTs, Structured Lipids) (CRADAOAL)

Keywords

• Professional dietary supplements
• Functional medicine nutrition
• Practitioner-only supplements
• Liposomal vitamin formulations
• Herbal bud extracts

Headquarters

HQ city

Irvine

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Professional Dietary Supplements: Sale of professional-grade nutritional supplements directly to healthcare professionals who then dispense to patients under their care. Products support specific biochemical pathways and physiological processes including neuroendocrine-immune axis, brain-gut axis, hepatic detoxification, brain chemistry, and functional blood chemistry.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels3 records

Core offering

Apex Energetics manufactures and sells professional-grade nutritional supplements exclusively to approved healthcare professionals, who dispense them to patients under their direct care. Its portfolio spans three product lines—K-Line Nutritionals™, TerrainZyme™ Z-Plex, and Herbal H-Plex—organized by physiological support areas such as blood sugar, brain, cellular, cardiovascular, endocrine, gastrointestinal, hepatobiliary, immune, musculoskeletal, occasional stress, urinary, and protein support. The formulations combine phytonutrients, cofactors, enzymes, amino acids, and botanicals developed with a Scientific Advisory Board and manufactured under cGMP.

Product overview

Apex Energetics is a professional dietary supplement company that offers three main product lines: K-Line Nutritionals™, TerrainZyme™ Z-Plex, and Herbal H-Plex. The K-Line Nutritionals line includes comprehensive physiological support products organized by body systems (Blood Sugar, Brain, Cellular, Cardiovascular, Endocrine, Gastrointestinal, Hepatobiliary, Immune System, Musculoskeletal, Occasional Stress, Urinary, Protein Support). Key products include ClearVite formulas (CHC, CLA, GL, PCH, PSF, GLB) for gastrointestinal and metabolic support, Brain support products like Acetyl-CH Active, Brain-E DHA, and CoQ10 SuperMax, and Immune System products such as ADEK-Pro and BioFilm CLR. TerrainZyme Z-Plex provides plant enzyme-based formulas (HCL Pro-Zyme, Immu-Zyme, Myco-Zyme, Puro-Zyme, Rena-Zyme) for biological terrain support. Herbal H-Plex offers European plant bud extracts (KDN-MAX, LIV-MAX, LMPH-MAX) for organ drainage and detoxification. All products are designed for healthcare professionals and their patients, emphasizing purity, performance, and quality with over 30 years of industry experience.

Differentiator

Problem solved

Functional benefit

Brands

• K-Line Nutritionals™: Professional nutritional line designed to support the endocrine system, gastrointestinal system, brain, brain-gut axis, circulatory system, hepatobiliary system, musculoskeletal system, and immune system with high-quality ingredients including phytonutrients, cofactors, and enzymes.
• TerrainZyme™ Z-Plex
• Herbal H-Plex

Products and services

• K-Line Nutritionals™ Professional nutritional line designed by healthcare professionals to support the endocrine system, gastrointestinal system, brain, brain-gut axis, circulatory system, hepatobiliary system, musculoskeletal system, and immune system with high-quality ingredients including phytonutrients, cofactors, and enzymes.
• TerrainZyme™ Z-Plex Highly advanced, plant enzyme-based nutritional line designed specifically to support the biological terrain with broad-spectrum enzymes to address mineral/electrolyte balance and enzymatic activity.
• Herbal H-Plex Product line designed for support of key filtering organs and their natural drainage processes using herbal ingredients picked at the plant bud's embryonic stage, including bud extracts from Europe for supporting drainage and detox.
• ClearVite-CHC™ Chocolate Advanced formulation containing collagen-based protein and targeted amino acids intended to support intestines, liver detoxication, and sugar metabolism.
• ClearVite-CLA™ Advanced formulation containing collagen-based protein and targeted amino acids intended to support intestines, liver detoxication, and sugar metabolism.
• ClearVite-GL™ Natural Berry Flavor Gastrointestinal and metabolic support formula based on the popular ClearVite formula, excluding sources of rice and pea protein for those with sensitivities.
• ClearVite-GL™ Natural Vanilla Flavor Gastrointestinal and metabolic support formula excluding rice and pea protein sources, designed for those with grain or pea sensitivities.
• ClearVite-PCH™ Chocolate Supports liver detoxication reactions, biliary system, and sugar metabolism by offering hypoallergenic nutrients, enzymatic cofactors, metabolic precursors, and phytonutrients.
• ClearVite-PSF™ Supports liver detoxication reactions, biliary system, and sugar metabolism with hypoallergenic nutrients and phytonutrients.
• Fibromin™ Helps support the colon, sugar metabolism, and lipid metabolism with a spectrum of soluble and insoluble fibers.
• GlycemoVite™ Supports sugar metabolism through a complex formula incorporating minerals, fibers, branched chain amino acids, and plant sterols.
• Glycoberine-MX™ Approach to supporting AMPK activity for metabolic health, combining burdock root with berberine HCl and Alpha Lipoic Acid Complex.
• Acetyl-CH™ Active Supports the cholinergic system and acetylcholine biosynthesis through select botanicals, enzyme cofactors, and acetylcholine precursors.
• AcetylFlo™ Oral spray intended to support the cholinergic system with N-acetyl L-carnitine, alpha-GPC, and the active form of vitamin B6.
• AC-Glutathione 250™ Supports intracellular antioxidant processes with 250 mg per capsule of S-acetyl L-glutathione designed for greater stability and bioavailability.
• AC-Glutathione™ Supports intracellular antioxidant processes with 125 mg per capsule of S-acetyl L-glutathione.
• B12-Max™ High-potency B12 supplement useful for vitamin B12 augmentation, containing 1250 mcg of methylcobalamin.
• Brain-E™ DHA High quality omega-3 fish oil providing 1200 mg of DHA per serving vital to brain health and function.
• Brain-E™ DHA 1200-TG IFOS and GOED certified omega-3 fish oil providing 1200 mg of DHA per serving in softgel form.
• Catecostim™ Supports the catecholaminergic system using key nutrients and precursors, with ingredients supporting brain function related to working memory, focus, and alertness.
• CoQ10 SuperMax™ Mitochondria-targeting formula promoting cardiovascular health and cognitive function with 400 mg CoQ10, 150 mg GG-Gold, and 20 mg PQQ per serving.
• C Liquazome™ Great tasting formula using proprietary liposomal process to deliver highly bioavailable vitamin C.
• C Liquazome™ 30-Packet Box Liposomal vitamin C formula available in single-serving packets.
• CoQ10-SM SuperMax™ Mitochondria-targeting formula in 30-softgel bottle promoting cardiovascular health and cognitive function.
• Cholestar-RF™ Helps maintain healthy cholesterol levels already in the normal range with inositol hexanicotinate, garlic extract, and pantethine.
• C-Zyme 1000™ Supports immune function and nonheme iron absorption with 1000 mg of buffered antioxidant vitamin C.
• Glycoberine™ Active Versatile formula delivering 500 mg of berberine per capsule supporting peripheral glucose uptake and healthy lipid metabolism.
• Adaptocrine™ Formulated to counter the metabolic effects of temporary stress and support the body when energetically spent.
• Adaptocrine™ XL Formulated to counter the metabolic effects of temporary stress with science-based selection of plant extracts including Panax ginseng, rhodiola, ashwagandha, and holy basil.
• Adreno-Zyme™ Supports demands of an active lifestyle with nutrients, cofactors, and bovine glandular support for adrenals, pituitary, and spleen.
• ClearVite-GLB™ Offers gastrointestinal and metabolic support with over 2 grams of targeted amino acids per serving, excluding rice and pea protein.
• BileMin™ Provides support for multiple aspects of the biliary system with phytonutrients and plant-based enzymes, including over 90 mg of standardized phospholipids.
• ADEK-Pro™ Supports gastrointestinal health and immune system combining vitamins A, D, E, and K in targeted ratios.
• AD-Pro™ Supports gastrointestinal health and immune system with high-potency antioxidant vitamin A and vitamin D3.
• BioFilm CLR™ Enzymatic powerhouse featuring proteolytic enzymes including trypsin, nattokinase, serratiopeptidase, and lumbrokinase to disrupt microbial biofilms.
• Collagen ProteinVite™ Supports energy metabolism and protein intake through hydrolyzed collagen protein with protease enzyme for protein breakdown.
• Mg/K-Zyme™ Supports body during transient stress with two forms of magnesium—aspartate and citrate—and potassium.
• NeurO2™ Uniquely designed to support cerebral microvasculature for healthy blood flow to the brain using high quality standardized extracts.
• Neurosera™ Addresses sleep and mood with complementary botanicals supporting GABA and serotonergic systems with compounds for relaxation and serenity.
• Neurosera™-SM Sleep and mood support formula with botanicals targeting key neurologic-based mechanisms in larger 2 oz size.
• Stress-Zyme™ Nutritional support during periods of high physical or mental stress with botanicals, minerals, and 5-HTP.
• Super B12™ Advanced liposomal B12 formula with 1,500 mcg of methylcobalamin per serving for healthy methylation.
• Bladder Serene™ Calming formula combining phytosterols with pumpkin seed extract and magnesium to support healthy urinary function.
• Prosta-DHT™ Unique formula for sustaining long-term prostate health and urinary comfort with botanicals and targeted nutrients.
• HCL Pro-Zyme™ Supports digestive processes through 500 mg of betaine HCl and proprietary blend of key ingredients including herbs and enzymes.
• Immu-Zyme™ Advanced herbal and colostrum immune-support formula with astragalus root extract and key immune-supportive ingredients.
• Myco-Zyme™ Designed to support intestinal terrain and gut flora balance with herbal formula including pau d'arco, garlic, and long pepper fruit.
• Puro-Zyme™ Supports blood and cellular health with key minerals, herbs, and proteolytic enzymes including willow bark, red clover, and burdock.
• Rena-Zyme™ Supports the kidneys with a nutritional-herbal complex.
• KDN-MAX™ Intended to support the urinary system with European plant bud extracts.
• LIV-MAX™ Intended to support the liver's natural excretory function and detoxification efficiency.
• LMPH-MAX™ Essential first-line herbal formula for all individuals supporting drainage and detox.

Quantifiable outcome

• 45-day supply per bottle of CoQ10 SuperMax

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Six partnerships are on record, tiered core.

• Datis Kharrazian (PhD, DHSc, DC, MS, MMSc, FACN)coreStrategic or Co-development PartnerDr. Kharrazian is one of the most sought-after experts in complementary medicine with expertise in functional blood chemistry, endocrinology, immunology, and neurology. He serves on the Scientific Advisory Board and has benefited Apex Energetics with valuable clinical observations, insights, and effective clinical protocols.
• Roy Martina (MD, Europe)coreStrategic or Co-development PartnerOne of the guiding lights of holistic medicine internationally with 35 years of clinical experience and over 50 books written. He lectures internationally and focuses on mind for self-healing, preventative healthcare, detoxification, anti-aging therapies, and personal development.
• Michael Galitzer (MD)coreStrategic or Co-development PartnerBoard certified in emergency medicine and graduate of UCLA's medical acupuncture program. Has been a Scientific Advisory Board member to Apex Energetics for over 20 years and has been instrumental in the development of various products, protocols, and educational materials.
• Chris Ahmadi (MD, Asia)coreStrategic or Co-development PartnerGraduate of Tehran University of Medical Sciences. Leads a research team to promote health and wellness and is instrumental in establishing and maintaining the high scientific standards of Apex Energetics.
• Stephen Stiteler (LAc, OMD, NMD, DHom, DOHAI, DBATCM, DANMA)coreStrategic or Co-development PartnerLicensed acupuncturist with doctorate in homeopathy and Oriental and naturopathic medicine. Creator of the Bio-Terrain System and has been responsible for the development of many of Apex Energetics' nutritional and homeopathic formulas, as well as educational strategies.
• American River Nutrition, LLC (GG-Gold™)coreTechnology or IntegrationLicensor of GG-Gold™ trademark, a patented form of geranylgeraniol extracted from the annatto plant. Protected by US Patents 7,989,006 and 8,293,290.

Scale indicators1 record

Recent moves6 records

Expansion highlights4 records

Direct peers

• Designs for Health: Direct peer — practitioner-only professional supplement brand offering a broad physiological-support catalog with similar functional medicine positioning to Apex Energetics.
• Pure Encapsulations: Direct peer — Pure Encapsulations (owned by Nestlé Health Science) is one of the largest professional-grade supplement brands sold exclusively through healthcare practitioners, overlapping directly with Apex's core channels and categories.
• Thorne: Direct peer — Thorne is a science-led, practitioner-recommended supplement brand with comparable quality standards (NSF/NPA certification), overlapping product categories (cognitive, metabolic, GI), and similar healthcare-professional positioning.
• Metagenics: Direct peer — Metagenics is a long-established practitioner-only supplement and medical food brand with similar functional/integrative medicine distribution and comparable breadth across physiological systems.
• Integrative Therapeutics: Direct peer — Integrative Therapeutics is a professional supplement brand distributed through licensed healthcare practitioners with a catalog that overlaps Apex's clinical-positioning supplements across multiple body systems.
• Xymogen: Direct peer — Xymogen is a practitioner-exclusive supplement manufacturer with a similarly broad physiological catalog and an exclusive online-only ordering model that mirrors Apex's professional distribution approach.
• Ortho Molecular Products: Direct peer — Ortho Molecular Products is a practitioner-only supplement company founded on evidence-based formulations, comparable to Apex in target customer (licensed practitioners) and breadth across physiological support categories.
• Standard Process: Direct peer — Standard Process is a whole-food and professional supplement company selling primarily to chiropractors and integrative practitioners, sharing Apex's practitioner channel and whole-system physiological support approach.
• Allergy Research Group: Direct peer — Allergy Research Group / NutriCology is a practitioner-channel supplement brand with a long history of practitioner-supplied formulations overlapping Apex's professional-grade, hypoallergenic, and metabolic categories.

Broad incumbents

• Life Extension: Broad incumbent — Life Extension is a larger, well-funded supplement company that overlaps with Apex on cognitive, mitochondrial (CoQ10), and metabolic categories, but sells both direct-to-consumer and through practitioners, giving it wider reach.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/apex-energetics

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Apex Energetics