Sequence Health

What Sequence Health does

Sequence Health, operating commercially as Guideway Care, is a privately held healthcare services company founded in 2004 and headquartered in Birmingham, Alabama, with medical contact center operations in Cullman, Alabama. The company provides patient activation services to hospitals, health systems, medical practices, Federally Qualified Health Centers, and health plans. Its central premise is that healthcare organizations lose patients at every friction point — missed calls, no-shows, incomplete follow-ups, ER overuse — and that closing the "activation gap" between patient intention and completed care action drives both better outcomes and recovered revenue. Named enterprise customers include Ascension, Northwell Health, and CommonSpirit Health, with the company serving what it describes as "hundreds of clients" across four primary vertical segments.

The company's platform is built around two proprietary assets: the Motivational Patient Guidance (MPG) framework, which codifies nine evidence-based behavioral techniques (including Motivational Interviewing, Choice Architecture, Reciprocity & Goodwill, and Contrast & Framing) into agent workflows, and the Enterprise GPS platform, an AI-driven orchestration layer that continuously monitors patient journeys, builds motivational profiles, and selects the next best action in real time. Licensed RNs deliver 24/7 clinical triage using gold-standard Schmitt-Thompson protocols, while trained non-clinical Activation Agents handle scheduling, barrier resolution, insurance verification, and proactive outreach. These systems integrate directly into client EHR systems — Epic, Cerner, Athenahealth, NextGen, and eClinicalWorks — for real-time documentation. The product suite spans seven integrated offerings: nurse triage, medical contact center, patient care coordination, appointment scheduling, after-hours support, insurance verification, and CMS-reimbursable care management (CCM, TCM, PCM, RPM, AWV).

Sequence Health generates revenue through quote-based B2B subscription or managed services contracts, typically structured as multi-year agreements with healthcare provider and payer organizations. Pricing is custom and not publicly disclosed, built around organization size, specialty mix, and patient population. The go-to-market motion is direct enterprise sales supported by inside sales for mid-market practices, augmented by participation in healthcare industry events (HIMSS, ObesityWeek, ASMBS) and a content-driven demand generation engine. The company holds HIPAA, SOC 2 Type II, and NIST 800-53 certifications, operates with 101–250 employees, and has undergone at least one material leadership transition — the 2017 appointment of Alan Creighton as CEO following founder Rosenzweig's retirement.

Name

Sequence Health

Legal name

Guideway Care

Website

https://sequencehealth.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

101–250 employees

Short description

Sequence Health (operating as Guideway Care) is a Birmingham, Alabama-based patient activation company providing AI-enhanced nurse triage, contact center, scheduling, and care management services to hospitals, practices, FQHCs, and payers through its Enterprise GPS platform and Motivational Patient Guidance framework.

Ownership category

akta.pro rank

Product category

Healthcare Patient Activation Services

NAICS

All Other Outpatient Care Centers (621498)

SIC

Services-Health Services (8000), Services-Computer Programming, Data Processing, Etc. (7370)

akta.pro primary industry

Nurse Triage & Clinical Call-Center Teletriage Platforms (HLALAJAC)

akta.pro secondary industries

Adherence, Reminders & Engagement Automation (Medication/Follow-up) (HLACAEAJ), Diagnostic & Triage Decision Support (HLACAGAA), Virtual Urgent Care & Triage Platforms (HLALABAB), Patient Intake, Digital Registration & eForms (HLACAEAF)

Keywords

• Patient activation services
• Nurse triage solutions
• Medical contact center
• Healthcare care coordination
• Patient engagement platform

Headquarters

HQ city

Atlanta

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Patient Activation Services - B2B Subscription/Managed Services: Guideway Care provides patient activation services to healthcare organizations on a subscription or managed services basis. Services include nurse triage, medical contact center, patient care coordination, appointment scheduling, after-hours support, insurance verification, and care management. Revenue is generated through contractual agreements with healthcare providers, health systems, FQHCs, and payers. Typical onboarding takes 4-6 weeks with dedicated implementation support.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Sequence Health delivers healthcare-only patient activation services through a unified platform of seven solutions — 24/7 nurse triage, medical contact center operations, patient care coordination, multi-specialty appointment scheduling, after-hours coverage, insurance verification, and CMS-reimbursable care management programs. Services are powered by the proprietary Enterprise GPS AI platform and the Motivational Patient Guidance (MPG) behavioral framework, with licensed RNs and trained Activation Agents executing clinically sound and behaviorally optimized patient interactions.

Product overview

Sequence Health (operating as Guideway Care) is a patient activation company offering a unified platform of healthcare contact center services powered by proprietary behavioral science and AI technology. The core offering consists of seven integrated solutions: Nurse Triage, Medical Contact Center, Patient Care Coordination, Appointment Scheduling, After-Hours Support, Insurance Verification, and Care Management—all unified through the Enterprise GPS platform and Motivational Patient Guidance (MPG) framework. This architecture delivers AI-enhanced human guidance where the platform continuously monitors patient journeys and selects optimal interventions, while licensed RNs and trained Activation Agents execute personalized patient interactions. All services integrate with major EHR systems including Epic, Cerner, Athenahealth, NextGen, and eClinicalWorks for real-time documentation within existing clinical workflows.

Differentiator

Problem solved

Functional benefit

Brands

• Sequence: Technology platform enabling patient activation workflows and intelligent orchestration
• Enterprise GPS
• Sequence of Activation
• Motivational Patient Guidance (MPG)

Products and services

• Nurse Triage Solutions 24/7 clinical assessment and care advice delivered by licensed RNs using gold-standard Schmitt-Thompson protocols, with every triage call both clinically sound and behaviorally optimized to drive patients toward completed next steps. Designed for hospitals, health systems, practices, and FQHCs needing after-hours coverage and reduced unnecessary ER visits.
• Medical Contact Center Solutions Centralized patient access hub providing a single point of contact for appointment scheduling, referral management, and post-discharge follow-up, with trained Activation Agents and AI-driven workflows ensuring every interaction drives a completed next step. Built for healthcare organizations replacing or augmentating in-house call center operations.
• Patient Care Coordination Solutions Dedicated coordinators embedded directly in healthcare organization workflows, working inside scheduling books and EHR systems to handle scheduling, insurance verification, pre-procedure instructions, warm transfers, and patient follow-ups as an extension of in-house staff. Targets practices and health systems with overwhelmed front desks.
• Appointment Scheduling Solutions Multi-specialty scheduling service featuring real-time availability, automated reminders, and proactive rescheduling powered by choice architecture and micro-commitment design to make booking the path of least resistance and prevent no-shows. Used by practices and health systems across multiple specialties.
• After-Hours Support Solutions 24/7/365 patient access coverage with continuous RN-level clinical support and activation-driven patient outreach, including holidays, to close after-hours gaps, reduce unnecessary ER visits, and support post-discharge patients outside business hours. Designed for hospitals, health systems, and practices.
• Insurance Verification Solutions Proactive eligibility and benefits confirmation service ensuring every patient visit starts with verified coverage, including eligibility checks, benefits confirmation, prior authorization support, and denial prevention. Reduces claim denials, billing surprises, and front-desk bottlenecks for practices and health systems.
• Care Management Delivers the five CMS-reimbursable care management programs — Chronic Care Management, Transitional Care Management, Principal Care Management, Remote Patient Management, and Annual Wellness Visits — through a single activation infrastructure, single team, and single EHR integration. Helps healthcare organizations generate connected revenue while activating patients toward completed next steps.
• Enterprise GPS Platform AI-powered proprietary platform that continuously monitors each patient journey, builds motivational profiles, and selects the next best action in real time, escalating to human Activation Agents when empathy matters more than efficiency. Powers predictive risk scoring, real-time sentiment analysis, and automated follow-up triggers across all Guideway Care services.

Quantifiable outcome

• 99.4% QA pass rate consistently above industry benchmarks
• +8 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration5 records

AI capability6 records

Feature6 records

Partnerships

One partnership is on record.

• EHR Vendors (Epic, Cerner, Athenahealth, NextGen, eClinicalWorks)coreTechnology or IntegrationTechnical integrations with all major Electronic Health Record systems enabling real-time booking, documentation, and workflow integration. Agents work directly in scheduling systems following provider rules with results visible to healthcare teams immediately.

Scale indicators11 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Carenet Health: Carenet Health is a healthcare-focused BPO providing 24/7 nurse triage, patient engagement, care coordination, and member support to health plans and providers — directly comparable as a clinical contact-center and patient activation vendor serving the same enterprise buyer.
• TriageLogic: TriageLogic offers nurse triage, after-hours call center services, and telehealth triage software using Schmitt-Thompson protocols to physician practices and hospitals — directly overlapping with Sequence Health's nurse triage and after-hours support offerings.
• CipherHealth: CipherHealth provides patient outreach, rounding, and care coordination platforms to hospitals and health systems. Its post-discharge follow-up, appointment reminders, and patient engagement workflows compete head-to-head with Sequence Health's Medical Contact Center and Patient Care Coordination solutions.
• Relatient: Relatient is a patient engagement platform focused on appointment scheduling, reminders, broadcast messaging, and patient outreach for practices and health systems — a direct competitor in the patient activation and scheduling segment.
• Medcor: Medcor operates 24/7 nurse triage, telehealth, and occupational health call centers for employers, hospitals, and clinics using proprietary clinical protocols — a comparable clinical contact-center peer with similar delivery model and customer segments.

Emerging players

• Bright.md: Bright.md builds AI-powered virtual care and automated patient intake/triage solutions for health systems. Its AI-driven clinical interview and triage approach overlaps with Sequence Health's Enterprise GPS AI orchestration and nurse triage capability, though focused more on synchronous self-service.
• PatientPop (by Tebra): PatientPop, now part of Tebra, offers practice growth, patient scheduling, reminders, and digital patient intake to physician practices. It overlaps with Sequence Health's scheduling and reminder capabilities, though more oriented to practice-side SaaS than outsourced services.
• LVM Systems: LVM Systems provides healthcare call center software and nurse triage solutions (CareWire, MedConnect) to hospitals and physician practices. It is a smaller direct competitor in the EHR-integrated nurse triage and patient communication niche.

Broad incumbents

• Stericycle Communication Solutions: Stericycle (now specializing in healthcare communication solutions after the 2024 divestiture) provides after-hours answering, nurse triage, and patient communication services for medical practices. It is a broader incumbent in the healthcare call center space overlapping with Sequence Health's medical contact center.

Others

• Health Catalyst: Health Catalyst is a healthcare data and analytics platform serving hospitals and health systems. While not a direct competitor, it intersects with Sequence Health's value-based care and care management thesis through population health and outcome measurement tooling.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/weareseqhealth
• Facebookfacebook.com/wearesequence
• LinkedInlinkedin.com/company/wearesequence

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Sequence Health