What Hanabusa IVF does

Hanabusa IVF is a private fertility clinic headquartered at 4910 Directors Place, Suite 150, in San Diego, California, founded in 2015 through a collaboration between Lyndon Chang, MD, FACOG and Masahide Shiotani, MD, PhD of Hanabusa Women's Clinic in Kobe, Japan. The clinic specializes in Japanese-inspired minimal stimulation IVF (Mini IVF), natural cycle IVF, and individualized stimulation protocols targeting egg quality over egg quantity, with particular focus on complex fertility cases including diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), advanced maternal age (40+), recurrent pregnancy loss, and patients who have experienced prior failed IVF cycles at other clinics. Technical differentiators include ultra-fine 20-21 gauge Japanese-made retrieval needles, an option for egg retrieval without IV sedation, and 10+ years of vitrification expertise; the laboratory holds CAP, ABB, FDA, and CDC accreditations. The clinic operates a comprehensive service portfolio spanning traditional fertility care (IVF, IUI, FET, egg freezing), complex care pathways (DOR, POI, PRP ovarian rejuvenation, fertility after 40), and third-party reproduction (donor egg, donor embryo, surrogacy, LGBTQ+ family building, gender selection via PGT).

Hanabusa IVF generates revenue primarily through per-cycle service billing for IVF (including Mini IVF and Natural Cycle IVF), frozen embryo transfers, IUI, egg freezing, PGT coordination, and third-party reproduction coordination, with patient financing facilitated through third-party partners (CapexMD, LendingClub Patient Solutions, Sunfish) and insurance accepted from Aetna, Cigna, and UnitedHealthcare (for Dr. LeBlanc). The clinic serves as the dedicated laboratory for Asian Egg Bank, a specialized donor egg bank focused on Asian patients, and operates an International Patient Program supporting out-of-town and global patients. Distribution is entirely direct through the single San Diego clinic, with patient acquisition driven by virtual physician consultations, phone nurse orientations, in-office visits, content marketing, organic social (Facebook, LinkedIn, Instagram, YouTube, TikTok), community events (RESOLVE Walk of Hope), and review platforms (Google, FertilityIQ). In March 2026, Hanabusa IVF and Asian Egg Bank were acquired by CSG.BIO, a global life sciences and healthcare platform, with Provident Healthcare Partners advising on the transaction.

Name

Hanabusa IVF

Legal name

Hanabusa IVF

Website

https://hanabusaivf.com

Company type

Private

Founded year

2015

Operating status

Operating

Headcount range

11–50 employees

Short description

Hanabusa IVF is a San Diego fertility clinic specializing in Japanese-inspired minimal stimulation IVF (Mini IVF) and complex fertility cases including diminished ovarian reserve, premature ovarian insufficiency, and advanced maternal age. Acquired by CSG.BIO in March 2026, it serves as the dedicated lab for Asian Egg Bank.

Ownership category

akta.pro rank

Product category

Fertility Clinic Services

NAICS

Family Planning Centers (621410), Blood and Organ Banks (621991)

SIC

Services-Misc Health & Allied Services, Nec (8090), Services-Medical Laboratories (8071)

akta.pro primary industry

Fertility, Reproductive Endocrinology & IVF Centers (HLAFAJAD)

akta.pro secondary industry

Reproductive Endocrinology & Infertility (IVF/Fertility) (HLAKAJAC)

Keywords

• Fertility clinic services
• In vitro fertilization
• Egg freezing services
• Fertility preservation
• Assisted reproductive technology

Headquarters

HQ city

San Diego

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales, Supply Chain

Revenue model

1. IVF and Fertility Treatment Services: Core revenue from IVF cycles (including Mini IVF and Natural Cycle IVF), frozen embryo transfers, IUI, egg freezing, and related fertility procedures. Services billed per cycle with component-based pricing.
2. Third-Party Reproduction Coordination: Donor egg program, surrogacy coordination, and gestational carrier services when appropriate through trusted partners. Additional coordination fees for external agency/legal costs.
3. Genetic Testing Services: PGT (Preimplantation Genetic Testing) coordination with external genetic testing labs, including biopsy and lab handling fees.
4. Financing Partnerships: Third-party financing partners (CapexMD, LendingClub Patient Solutions, Sunfish) provide patient financing for IVF cycle fees, with the clinic facilitating but not directly providing financing.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels10 records

Core offering

Hanabusa IVF is a San Diego fertility clinic providing comprehensive fertility care for individuals and couples, anchored by Japanese-inspired Minimal Stimulation IVF (Mini IVF) and including Traditional IVF, Natural Cycle IVF, IUI, Frozen Embryo Transfer, egg freezing, donor egg/embryo programs, surrogacy coordination, PGT, LGBTQ+ family building, and complex care pathways for DOR, POI, advanced maternal age, recurrent pregnancy loss, and prior failed IVF. The clinic operates a CAP/ABB/FDA/CDC-accredited embryology laboratory with 10+ years of vitrification expertise and serves as the dedicated lab for Asian Egg Bank.

Product overview

Hanabusa IVF offers a comprehensive, multi-tiered fertility care platform centered on individualized treatment protocols. The core portfolio spans Traditional Care services (IVF, IUI, FET, egg freezing) and Complex Care pathways (DOR, POI, PRP Ovarian Rejuvenation, Fertility After 40, Failed IVF support). The clinic specializes in Japanese-informed Minimal Stimulation IVF (Mini IVF) and Natural Cycle IVF, using ultra-fine retrieval needles and no-sedation retrieval options. Supporting services include Donor Egg/Embryo Programs, Surrogacy, LGBTQ+ Family Building, Gender Selection via PGT, and Male Infertility services. The laboratory provides vitrification (10+ years expertise), and the clinic serves as the dedicated lab for Asian Egg Bank. Post-treatment, graduates receive complimentary cord blood banking through AlphaCord. The Horizon Program provides structured financial assistance for time-sensitive cases. In March 2026, Hanabusa IVF and Asian Egg Bank joined CSG.BIO, a global life sciences platform.

Differentiator

Problem solved

Functional benefit

Products and services

• Mini IVF Japanese-inspired minimal stimulation IVF using targeted, lower-dose medications to support controlled follicle development, focusing on egg quality over egg quantity and personalized to ovarian response, timing, and goals. Designed for patients with complex ovarian reserve cases and those seeking a gentler alternative to conventional IVF.
• Traditional IVF Full-service in vitro fertilization including ovarian stimulation, egg retrieval, fertilization, embryo culture, and transfer for patients with straightforward fertility indications.
• Natural Cycle IVF IVF approach without medication stimulation, collecting the single egg naturally produced in a menstrual cycle for patients seeking minimal intervention.
• IUI (Intrauterine Insemination) Artificial insemination procedure placing sperm directly into the uterus, often including monitoring and timing support.
• Frozen Embryo Transfer (FET) Transfer of previously frozen embryos into the uterus, including uterine preparation planning, monitoring, thawing, and transfer procedures.
• PGT (Preimplantation Genetic Testing) Genetic testing of embryos before transfer, including PGT-A for chromosomal abnormalities, to identify euploid embryos and inform treatment decisions.
• Diminished Ovarian Reserve (DOR) Care Specialized treatment pathway for patients with low ovarian reserve, offering individualized stimulation protocols including minimal stimulation approaches.
• Premature Ovarian Insufficiency (POI) Treatment Care pathway for patients with premature ovarian insufficiency or failure, including treatment options beyond donor egg.
• Ovarian Rejuvenation with PRP Platelet-rich plasma (PRP) based ovarian rejuvenation treatment aimed at improving ovarian function and egg quality for patients with diminished ovarian reserve or premature ovarian insufficiency.
• Donor Egg Program Donor egg services for patients requiring donor eggs, including coordination and matching with Asian donor options through Asian Egg Bank.
• Donor Embryo Program Embryo donation services providing donated embryos to patients who need them for family building.
• Egg Freezing Fertility preservation through egg freezing using vitrification, including services for cancer patients and elective egg freezing.
• Surrogacy Program Gestational carrier and surrogacy coordination services for patients who cannot carry a pregnancy themselves.
• LGBTQ+ Family Building Fertility services specifically designed for LGBTQ+ individuals and couples, including reciprocal IVF and other family-building options.
• Gender Selection Family balancing and gender selection services using PGT technology to select embryos of a specific sex.
• Male Infertility Services Male factor support including semen analysis review and ICSI planning when clinically appropriate.
• Fertility After 40 Specialized care pathway for patients over 40 seeking fertility treatment, including individualized protocols for advanced maternal age.
• Recurrent Pregnancy Loss Care Structured evaluation and individualized next-step planning for patients experiencing two or more pregnancy losses.
• Failed IVF Second Opinion Consultation and strategy development for patients who have experienced unsuccessful IVF cycles at other clinics.
• Low Complexity IVF Simplified IVF approach for patients with fewer complicating factors, offering a less intensive treatment pathway.
• Horizon Program Financial assistance pathway for time-sensitive fertility patients, particularly those with diminished ovarian reserve who are still menstruating, and required for patients age 45+. Includes up to 6 months of treatment or maximum 3 egg retrievals.
• International Patient Program Coordination and logistics support for international and out-of-town patients seeking fertility treatment, including scheduling and travel assistance.
• Asian Egg Bank Specialized egg bank focused on serving Asian patients with donor egg options, with Hanabusa IVF serving as the dedicated laboratory. Now part of the CSG.BIO platform following the March 2026 acquisition.
• Ultra-Fine Egg Retrieval Japanese-made ultra-fine retrieval needles (20-21 gauge) approximately half the thickness used at many IVF centers, designed to minimize tissue disruption with precision tip design and minimal pain and downtime.
• Egg Retrieval Without IV Sedation Minimally invasive egg retrieval option allowing procedures without general anesthesia, reducing anesthesia-related side effects, lowering cost by avoiding anesthesiologist fees, and eliminating escort requirements.

Quantifiable outcome

• 10+ years of vitrification focus with consistent freeze-thaw performance
• +2 more outcomes

Named customers5 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Six partnerships are on record, tiered core and minor.

• CSG.BIOcoreStrategic or Co-development Partner · 5 March 2026Hanabusa IVF and Asian Egg Bank were acquired by CSG.BIO, a global life sciences and healthcare platform, on March 5, 2026. The acquisition enhances CSG.BIO's reproductive medicine and biologic preservation capabilities, integrating specialized fertility, donor egg, surrogacy, and family-building services. The deal was advised by Provident Healthcare Partners and involved extended due diligence due to international ownership complexity.
• Asian Egg BankcoreStrategic or Co-development PartnerHanabusa IVF serves as the dedicated laboratory for Asian Egg Bank, a specialized donor egg bank serving Asian patients. The partnership combines Hanabusa IVF's mini-IVF clinical model with Asian Egg Bank's specialization in Asian donor options, creating a differentiated platform in the fertility market.
• AlphaCordminorGTM or Marketing PartnerAlphaCord provides complimentary newborn cord blood banking for every Hanabusa IVF graduate (patients who achieve pregnancy and deliver). This partnership offers graduating families biological protection from day one, as cord blood can be used to treat 80+ conditions.
• CapexMDminorGTM or Marketing PartnerThird-party financing partner providing loan products designed specifically for IVF, egg freezing, and related treatments. Subject to lender approval and terms.
• LendingClub Patient SolutionsminorGTM or Marketing PartnerThird-party financing partner offering patient loan solutions for fertility treatments. Subject to lender approval and terms.
• SunfishminorGTM or Marketing PartnerThird-party financing partner providing financing options for IVF cycle fees. Subject to lender approval and terms.

Scale indicators2 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• Kindbody: Tech-enabled fertility clinic chain with employer-benefit partnerships, full IVF/IUI/egg-freezing offering, and a national footprint. Comparable services but positioned as a modern, scalable, employer-anchored alternative.
• Shady Grove Fertility: One of the largest U.S. fertility clinic networks with broad insurance participation and a full IVF/IUI/donor/surrogacy offering. Comparable service breadth but with vastly broader geographic footprint and payer access.
• Prelude Fertility: Multi-clinic fertility platform offering IVF, egg freezing, and genetic services with broader geographic reach. Comparable in core IVF services but operates at greater scale and integration.
• CCRM Fertility: Large multi-site U.S. fertility network offering IVF, Mini IVF, egg freezing, and complex case treatment. Comparable in clinical menu and complex-case expertise but operates at significantly larger scale across many metros.
• Boston IVF / Reproductive Medicine Associates: Multi-site fertility networks offering IVF, Mini IVF, PGT, and donor programs with established research affiliations. Comparable clinical portfolio and complex-case positioning at larger scale.

Emerging players

• Extend Fertility: Fertility clinic with strong egg-freezing focus and a tech-forward brand. Overlaps with Hanabusa on egg freezing and elective fertility preservation but emphasizes a younger, prevention-oriented patient.

Direct peers

• Neway Fertility: Independent fertility clinic emphasizing minimal stimulation and natural cycle IVF protocols. Closest methodological peer to Hanabusa's Japanese-inspired Mini IVF approach.
• San Diego Fertility Center: Direct local competitor in the San Diego market offering full-service IVF, IUI, egg freezing, and donor services. Comparable in geography and product mix, competing for the same patient pool Hanabusa serves.
• Pacific Fertility Center: Full-service fertility clinic with strong complex-case expertise, comparable menu including IVF, egg freezing, donor services, and PGT. Most similar in scale, clinical positioning, and individualized approach.

Regional players

• Fertility Centers of Illinois: Large regional fertility network with comprehensive IVF, donor, and surrogacy services. Comparable service breadth but primarily competes in the Midwest rather than Hanabusa's West Coast and international markets.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@hanabusaivf
• Facebookfacebook.com/hanabusaivf
• LinkedInlinkedin.com/company/hanabusa-ivf
• Instagraminstagram.com/hanabusaivf/?hl=en
• TikToktiktok.com/@hanabusaivf
• Xx.com/hanabusaivf

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Hanabusa IVF