Substances Actives

What Substances Actives does

Substances Actives is a privately held French digital agency, founded circa 2010 and headquartered in Paris, that provides integrated digital marketing and patient-communication services exclusively to healthcare professionals, with a primary focus on dental surgeons and orthodontists and a secondary focus on general medical practitioners. The company's core offerings comprise three proprietary digital products: Visual Activ, a plug-and-play waiting-room TV system built around a France-developed hardware player, a web-based broadcast management platform, and a library of over 500 medical video clips validated by the UFSBD; Activ Review, an online reputation management application that aggregates Google reviews and patient satisfaction surveys; and Matisse, a cloud-based dental practice management software marketed with AI capabilities. These products are complemented by a portfolio of bespoke professional services including custom website development (compliant with French dental and medical association charters), visual identity creation, social media management, patient newsletters, photo and video production, and a custom clinic magazine (Smile Mag).

The business operates a subscription-and-project hybrid revenue model: Visual Activ, Activ Review, and Matisse generate recurring SaaS revenue, while websites, visual identity, and media production are delivered as one-time project engagements priced individually per client. Pricing is uniformly bespoke and quote-based, with no public tiers, and the go-to-market motion is sales-led inside sales targeting French SMB dental and medical practices, supported by direct outreach, website-driven inbound, Calendly-scheduled consultations, and thought-leadership PR in major French outlets (Le Figaro, Le Parisien, L'Express, Le Point, BFM Business). The firm is founder-led by CEO Mathieu Rouppert, employs approximately 10 people, and operates without disclosed external institutional funding, suggesting an organically grown small-cap business now actively pursuing European expansion through dedicated business development and customer success hiring.

Name

Substances Actives

Legal name

SAS Substances Actives

Website

https://substancesactives.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

Substances Actives is a Paris-based digital agency founded around 2010 that provides bespoke websites, waiting-room TV (Visual Activ), reputation management (Activ Review), and cloud dental software (Matisse) to SMB dental surgeons and medical practitioners in France.

Ownership category

akta.pro rank

Product category

Healthcare Digital Marketing Services and Practice Software

NAICS

Advertising Agencies (54181), Advertising, Public Relations, and Related Services (5418)

SIC

Services-Advertising Agencies (7311), Services-Advertising (7310)

akta.pro primary industry

Brand Activations & Experiential Campaign Design (MPAAAGAA)

Keywords

• Healthcare digital agency
• Dental practice marketing
• Practice management software
• Online reputation management
• Waiting room display solutions

Headquarters

HQ city

Paris

HQ country

France

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. Digital Marketing Services: Subscription-based and project-based digital services for healthcare professionals including custom website development, visual identity creation, social media management, photo/video reports, and magazine production. Services are priced as bespoke/quoted based on client requirements.
2. Software as a Service (SaaS): Recurring subscription services including Visual Activ (waiting room TV player and platform), Activ Review (online reputation management), and Matisse dental software. These operate on subscription or usage-based models with monthly/annual billing.
3. Professional Services: One-time professional services including website creation, visual identity design, photo/video production, and consulting engagements for digital strategy implementation.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels7 records

Core offering

Substances Actives is a Paris-based digital agency that sells SaaS products and digital marketing services dedicated to healthcare professionals in France. Its portfolio includes Visual Activ (waiting room TV displays), Activ Review (online reputation management), and Matisse (AI-powered dental practice management software), alongside custom services such as website design, visual identity, social media management, photo/video production, newsletters, and print magazines.

Product overview

Substances Actives is a digital marketing agency dedicated to healthcare professionals, offering a portfolio of products organized as two flagship digital applications (Visual Activ and Activ Review), a cloud dental practice management software (Matisse), complemented by a suite of digital services (custom websites, visual identity, social media management, photo/video production, newsletters, and a clinic magazine). The company also provides a free website SEO audit tool and Covid-19 communication kits as supplementary resources. The overall portfolio centers on digitizing the patient-practitioner relationship through waiting room TV, online reputation management, web presence, and communication services.

Differentiator

Problem solved

Functional benefit

Brands

• Visual Activ: Waiting room TV program for healthcare professionals that educates patients and highlights practitioner skills.
• Activ Review
• Matisse
• WebDentiste
• Smile Mag

Products and services

• Visual Activ

Quantifiable outcome

• Treatment plans better understood and accepted by patients using Visual Activ
• +2 more outcomes

Named customers7 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability3 records

Feature4 records

Partnerships

Ten partnerships are on record, tiered core and minor.

• EcoTreecoreStrategic or Co-development Partner · 1 January 2021Environmental partnership for carbon offset and forest preservation. Substances Actives planted 580 trees in French forests (Châtelain in Mayenne and Luthenay in Burgundy), having absorbed 8,200 kg of CO2. Also partnered on wetland restoration project in Morbihan for biodiversity preservation.
• UFSBD (Union Française pour la Santé Bucco-Dentaire)coreStrategic or Co-development PartnerLong-term partnership for oral health prevention. Visual Activ videos are reviewed and validated by UFSBD, reaching 150,000-200,000 patients monthly through dental practice waiting rooms.
• Time for the PlanetminorStrategic or Co-development PartnerSubstances Actives became shareholder of this non-profit company which aims to raise one billion euros to invest in environmental innovation.
• Planet Tech CareminorStrategic or Co-development PartnerCommitment initiative to transform the digital sector and make it more eco-friendly. Provides updates on sustainable digital discoveries.
• GandicoreTechnology or IntegrationWeb hosting provider for company and client websites. Gandi SAS hosts websites from 63-65 Boulevard Masséna, 75013 Paris.
• MatomocoreTechnology or IntegrationOpen-source web analytics platform chosen for RGPD compliance and CNIL recommendations. Provides complete data control and hosted on French servers (Scaleway).
• ScalewaycoreTechnology or IntegrationEco-responsible French hosting provider for web analytics data storage, complementing Matomo analytics platform.
• ZEI (Zero Waste Initiatives)minorOthersEnvironmental initiative partner featured on company footer, supporting environmental responsibility efforts.
• France DigitaleminorStrategic or Co-development PartnerMembership in European tech cluster organization that develops competitive tech while including environmental and social criteria.
• French Healthcare AssociationminorStrategic or Co-development PartnerPartnership with French Healthcare Association for healthcare industry networking and advocacy.

Scale indicators7 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Curve Dental: Cloud-based dental practice management SaaS serving SMB and mid-market practices. Direct competitor to Substances Actives' Matisse offering on the dental practice-software layer, with much larger scale and a US/global footprint.
• PatientPop (Tebra): US-based healthcare digital marketing platform offering websites, reputation management, scheduling, and patient communication for practices. Highly comparable to Substances Actives across website, reputation, and patient-communication product lines, though at significantly larger scale and primarily US-focused.
• tab32: Cloud-based dental practice management software with data analytics. Broad incumbent competing with Matisse on cloud dental software, primarily US-focused but serving a comparable SMB dental segment.
• Henry Schein One: Global dental practice management and marketing software portfolio (Dentrix, Jarvis Analytics, etc.). Broad incumbent competing in adjacent slots to Matisse and Activ Review with much deeper distribution and capital.
• Doctolib: France's dominant healthcare digital platform (appointment booking, teleconsultation, patient communication) and the most powerful broad incumbent in the French healthcare-professional digital stack that Substances Actives targets. Comparable because it sells digital patient-relationship tools to the same French SMB healthcare buyers, though it operates at much greater scale and breadth.

Emerging players

• DentalMonitoring: France-based dental AI company (remote monitoring, AI-driven clinical workflows). Emerging player with partial overlap on the AI-in-dentistry axis where Matisse positions itself, though focused on clinical workflows rather than practice marketing.

Direct peers

• Sesame Communications (Tebra): Dental-specialist marketing and patient communication platform acquired into the Tebra ecosystem. Direct vertical peer to Substances Actives' dental practice marketing and Visual Activ-style patient-communication offering.
• Officite: Healthcare-focused website design, SEO, and digital marketing agency serving dental and medical practices. Direct peer — comparable offering (custom healthcare websites + digital marketing services) targeting the same SMB healthcare-professional segment.
• ProSites: US dental-specialist digital marketing agency providing custom websites, SEO, and patient communication for dental practices. Direct vertical peer — both companies focus exclusively on digital services for dentists, with comparable offering structure (custom sites + add-on marketing services).

Regional players

• Doctena: European online appointment-booking and patient management platform for healthcare professionals. Comparable buyer (healthcare SMBs) and adjacent offering, but geographically focused on Benelux/Germany rather than France.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/substancesactiv

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Substances Actives