What CircO2 does

CircO2 is a single-product direct-to-consumer supplement brand owned and manufactured by Advanced Bionutritionals, LLC, a privately-held nutritional supplements company headquartered in Georgia, USA. The company sells a fast-dissolving nitric oxide booster lozenge positioned to address age-related decline in nitric oxide production, targeting health-conscious adults over 40 who experience reduced circulation, lower energy, and cardiovascular concerns, with secondary appeal to active adults seeking performance support. The product is sold in 1-box ($49.95), 3-box ($134.85), and 6-box ($249.00) bundles, backed by a 90-day money-back guarantee.

The core technology is a sublingual lozenge delivery system combining beetroot powder, L-citrulline, hawthorn berry extract, vitamin C, vitamin B12, magnesium, and sodium nitrite. The lozenge format is designed to engage with oral bacteria to convert nitrates into usable nitric oxide, a mechanism tied to MIT research indicating this conversion begins in the mouth rather than the gut. The product is manufactured in an FDA-registered, GMP-certified facility in Norcross, Georgia, and the company claims a 200% increase in nitric oxide levels within 20 minutes and a 34% increase in blood flow in clinical testing.

The business model is purely direct-to-consumer: CircO2 sells exclusively through its official website, with order processing and customer support handled via third-party platforms ClickBank and BuyGoods. Revenue consists entirely of one-time purchases with no subscription tier disclosed, supplemented by content marketing, social media presence, and customer testimonials. The company operates with 1-10 employees, has no disclosed external funding, and ships to the USA, Canada, and international markets.

Name

CircO2

Legal name

Advanced Bionutritionals, LLC

Website

https://en-eng-circo2.com

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Short description

CircO2 is a direct-to-consumer supplement brand of Advanced Bionutritionals selling a sublingual nitric oxide booster lozenge. It targets adults over 40 seeking improved circulation, natural energy, and cardiovascular support through its MIT-validated oral-bacteria delivery approach.

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Medicinal and Botanical Manufacturing (325411)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Functional Foods & Supplement Formats (Gummies, Chews, Powders, Shots) (CRADAGAI)

akta.pro secondary industry

Herbal & Botanical Supplements (CRADAGAD)

Keywords

• Nitric oxide supplements
• Circulation support supplements
• Sublingual lozenges
• Cardiovascular health supplements
• Dietary supplements

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Marketing or Sales, Operations, Personnel

Revenue model

1. Direct Supplement Sales: CircO2 generates revenue through direct-to-consumer sales of nitric oxide supplement lozenges. Products are sold in 1-box, 3-box, and 6-box bundles with tiered pricing that rewards larger purchases. Orders are processed through ClickBank and BuyGoods payment processors. The company offers a 90-day money-back guarantee.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

CircO2 is a fast-dissolving sublingual lozenge dietary supplement formulated to support the body's natural nitric oxide production for improved circulation, sustained energy, mental clarity, and cardiovascular health. The lozenge dissolves in the mouth and engages beneficial oral bacteria to convert nitrate-rich ingredients (beetroot powder, L-citrulline, hawthorn berry, vitamins C and B12) into usable nitric oxide, bypassing the digestive system. It is sold directly to consumers in 1-box, 3-box, and 6-box bundles via the official website.

Product overview

CircO2 is a single unified product — a natural nitric oxide booster supplement in fast-dissolving lozenge form, manufactured by Advanced Bionutritionals. The product is sold in three package options (1-Box, 3-Box, and 6-Box) and is distributed exclusively through the official website via payment processors ClickBank and BuyGoods. CircO2 contains a blend of nitric-oxide-supporting ingredients including beetroot powder, L-citrulline, hawthorn berry extract, vitamin C, vitamin B12, and sodium nitrite, delivered via a sublingual lozenge format that engages with oral bacteria for conversion.

Differentiator

Problem solved

Functional benefit

Products and services

• CircO2 Nitric Oxide Booster Lozenge CircO2 is a fast-dissolving sublingual lozenge dietary supplement designed to support natural nitric oxide production for improved circulation, sustained energy, mental clarity, and cardiovascular health. The lozenge dissolves in the mouth to engage beneficial oral bacteria that convert nitrate-rich ingredients into usable nitric oxide. It is sold in 1-box, 3-box, and 6-box bundle packages directly to consumers via the official website, with a 90-day money-back guarantee.

Quantifiable outcome

• Nitric oxide levels increased 200% within 20 minutes in clinical testing
• +2 more outcomes

Named customers7 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Three partnerships are on record, tiered core.

• Advanced BionutritionalscoreOEM/ Whitelabel/ Licensing PartnerAdvanced Bionutritionals is the parent company and manufacturer of CircO2. They formulate and produce the supplement in their FDA-registered, GMP-certified facility in Georgia. CircO2 is their flagship nitric oxide product featuring a sublingual lozenge delivery system.
• ClickBankcoreChannel Partner/ Reseller/ DistributorClickBank serves as the primary payment processor and retailer for CircO2 orders. They handle transaction processing, order fulfillment, customer support for delivery status, refunds, and subscription management. ClickBank is a registered trademark of Click Sales, Inc., headquartered in Boise, Idaho.
• BuyGoodscoreChannel Partner/ Reseller/ DistributorBuyGoods is an alternative payment processor and fulfillment partner for CircO2 orders. They handle recurring billing concerns, shipping updates, order tracking, and customer support for orders processed through their platform.

Scale indicators3 records

Recent moves5 records

Expansion highlights3 records

Broad incumbents

• NOW Foods: NOW Foods is a large supplement manufacturer and retailer offering L-citrulline, beetroot, and nitric oxide products at lower price points. Overlaps with CircO2 on ingredients and benefits, but at commodity pricing.
• Standard Process: Standard Process is a long-standing whole-food supplement manufacturer with cardiovascular and circulation-focused products. Overlaps in use case but distributed through practitioners and supplements professionals.
• Life Extension: Life Extension is a large, established supplement brand offering multiple nitric oxide and vascular health formulations. It competes in the same end benefit but as a broad portfolio player.

Others

• Advanced Bionutritionals: Advanced Bionutritionals is the parent company and manufacturer of CircO2. It is not a competitor but the producing entity—relevant for understanding corporate structure and shared manufacturing capability.

Direct peers

• HumanN: HumanN markets SuperBeets, a beetroot-based nitric oxide support product (powder and chews). It is the closest direct competitor to CircO2 in the nitrate-to-NO pathway, targeting similar circulation and energy benefits.
• NEO40 (NEO40 Professional): NEO40 is a daily nitric oxide lozenge leveraging the oral bacteria conversion pathway—the same biohack as CircO2. It is the most direct format and mechanism competitor.
• BeetElite: BeetElite sells concentrated beetroot-based performance supplements targeting nitric oxide production, endurance, and circulation. Competes directly for CircO2's active-adult segment.
• Neogenis Labs: Neogenis focuses exclusively on nitric oxide-based products supported by co-founder Dr. Nathan Bryan's research on the oral nitrate pathway. It is a direct mechanism-level competitor to CircO2.
• Berkeley Life: Berkeley Life sells nitrate-rich nitric oxide supplements (capsules and chewables) for circulation and blood pressure support. It directly competes with CircO2 on the same mechanism and customer demographic.

Emerging players

• Blood Flow Max / Pure Healthland: Blood Flow Max is an emerging DTC supplement brand targeting circulation and blood pressure using L-citrulline and beetroot. Similar positioning to CircO2 but with lower brand recognition.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat2 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/O2Circ50779
• YouTubeyoutube.com/c/circo2
• Facebookfacebook.com/circo2
• Pinterestpinterest.com/circo2

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about CircO2