The Naloxone Project

What The Naloxone Project does

The Naloxone Project (TNP) is a 501(c)(3) nonprofit organization founded in 2021 in Denver, Colorado, by Dr. Donald Stader, with the stated purpose of expanding naloxone access across healthcare, first response, and community settings to reduce opioid overdose deaths. The organization operates as a coordinated national platform of interconnected programs: an Emergency Department Program embedding take-home naloxone into hospital discharge workflows; the MOMs (Maternal Overdose Matters) Initiative focused on labor and delivery units; the Outpatient Clinic Program distributing naloxone to uninsured and underinsured patients across diverse specialties; PACC (Prehospital Addiction Care Consortium) for Fire, EMS, Law Enforcement, and Co-Response agencies; the RESPONSE Initiative for K-12 schools; and WY-NOW, a Wyoming workforce initiative targeting high-risk industries. TNP runs on a chapter-based expansion model that has scaled to 15 state chapters (Arizona, Colorado, Illinois, Kentucky, Maryland, Massachusetts, Missouri, Montana, Ohio, Oklahoma, Tennessee, Texas, Utah, Virginia, Washington, Wyoming) and has distributed more than 121,000 doses of naloxone since founding, including 59,000 in 2025 alone.

Underlying capabilities include a Six Pillars Framework (Naloxone Distribution, Data Excellence, Education, JEDI, Fiscal Responsibility, Legislative & Regulatory Advancement), mobile applications on iOS and Android, 24/7 naloxone vending machines, and integration with the OpiRescue/OpiSafe platform. The organization's revenue model is non-commercial: it relies on individual donations, corporate and foundation grants (Sandgaard Foundation, FORE Foundation, Direct Relief), state and federal government grants (Virginia Opioid Abatement Authority, Wyoming Department of Health, Tennessee Department of Health, Colorado legislation HB-22-1326 and HB-20-1066 enabling hospital reimbursement), and strategic pharmaceutical partnerships (Padagis, Hikma, FFF Enterprises) that provide lower-cost product supply rather than cash revenue. Distribution to end recipients is free. TNP operates with a lean core staff (reported as 1-10 employees) supplemented by directors and coordinators across programs and state chapters, and an active Board of Directors with heavy representation from emergency medicine and addiction medicine leadership.

Name

The Naloxone Project

Legal name

The Naloxone Project

Website

https://www.naloxoneproject.com

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

1–10 employees

Short description

The Naloxone Project is a Denver-based 501(c)(3) nonprofit founded in 2021 that distributes naloxone through hospitals, emergency departments, outpatient clinics, labor and delivery units, first responder agencies, schools, and vending machines, operating across 15 U.S. state chapters via grants and partnerships.

Ownership category

akta.pro rank

Product category

Harm Reduction Services

NAICS

Voluntary Health Organizations (813212)

akta.pro primary industry

Substance Use Disorder Prevention & Recovery Services (BPAGACAE)

akta.pro secondary industry

Substance Use Recovery & Harm Reduction Support Services (BPAGAEAO)

Keywords

• Naloxone distribution programs
• Harm reduction services
• Overdose prevention programs
• Opioid crisis response
• Public health nonprofit

Headquarters

HQ city

Denver

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Supply Chain, Others

Revenue model

1. Donations: Individual donations from supporters who want to contribute to ending the opioid epidemic. TNP accepts donations through its website to support take-home naloxone programs.
2. Government Grants and Funding: State-level funding from entities such as the Virginia Opioid Abatement Authority, Wyoming Department of Health, and Tennessee Dept of Health. Federal funding through legislation like HB-22-1326 and HB-20-1065 in Colorado that enables hospital-based naloxone reimbursement.
3. Pharmaceutical Partnerships: Partnerships with pharmaceutical companies like Padagis to expand access to lower-cost naloxone products across states. States receive lower-cost naloxone products along with TNP's expertise and support.
4. Corporate and Foundation Grants: Support from organizations including the Sandgaard Foundation and other corporate partners that fund the mission and operations.

Go-to-market motion2 records

Distribution channels7 records

Marketing channels8 records

Core offering

The Naloxone Project is a 501(c)(3) nonprofit that builds and operates hospital-, clinic-, first responder-, and community-based naloxone distribution programs across 15 U.S. state chapters. Its core offering combines take-home naloxone supply, implementation support, training, education toolkits, and data tracking to help healthcare systems and first responder agencies embed overdose prevention into routine workflows. Programs are provided free of charge to end recipients and sustained through grants, donations, and partnerships.

Product overview

The Naloxone Project is a 501(c)(3) nonprofit organization that operates as a coordinated national network with a platform of interconnected programs focused on naloxone distribution and overdose prevention. The core product portfolio consists of: (1) the Emergency Department Program, which embeds naloxone distribution into hospital emergency department workflows; (2) the MOMs Initiative, which focuses on labor and delivery units; (3) PACC (Prehospital Addiction Care Consortium), targeting first responders with naloxone leave-behind kits and buprenorphine induction; (4) the RESPONSE Initiative for school-based overdose preparedness; (5) the Outpatient Clinic Program; and (6) Naloxone Vending Machines for 24/7 community access. Supporting these programs are educational resources (how-to videos, FAQs, toolkits) and mobile applications. The organization expanded to 15 state chapters as of 2025, distributing over 121,000 doses of naloxone since founding in 2021, with 59,000 doses distributed in 2025 alone.

Differentiator

Problem solved

Functional benefit

Brands

• PACC (Prehospital Addiction Care Consortium): A systems-change approach to the opioid crisis focused on healthcare, public policy, and community, working with hospitals, clinics, first responders, and community organizations.
• MOMs (Maternal Overdose Matters) Initiative
• RESPONSE (Rapid Emergency System Planning for Overdoses iN School Environments)
• Emergency Departments Program
• Outpatient Clinic Program
• WY-NOW (Wyoming Naloxone, Overdose & Workforce Initiative)

Products and services

• Emergency Departments Program
• MOMs Initiative (Maternal Overdose Matters)
• PACC (Prehospital Addiction Care Consortium)
• Outpatient Clinic Program
• RESPONSE Initiative (Rapid Emergency System Planning for Overdoses iN School Environments)
• WY-NOW (Wyoming Naloxone, Overdose & Workforce Initiative)

Quantifiable outcome

• 121,000+ doses of naloxone distributed since founding, including 59,000 in 2025 alone
• +4 more outcomes

Named customers10 records

Segments6 records

Ideal customer profiles6 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

34 partnerships are on record, tiered core and major.

• PadagiscoreStrategic or Co-development Partner · 23 September 2025Partnership with generic pharmaceutical company Padagis to expand access to generic naloxone nasal spray across U.S. states. Through collaboration, states receive lower-cost naloxone products along with TNP's expertise and tailored support to enhance overdose prevention programs. Aims to address the opioid overdose crisis by providing affordable, widely available naloxone.
• American Medical AssociationcoreStrategic or Co-development PartnerPartnership to remove barriers to naloxone access. Joint initiative encouraging physicians to prescribe naloxone, making it available in schools, workplaces, and public spaces, and ensuring affordability. Initiative calls on health professionals, policymakers, employers, and communities to join in expanding naloxone distribution.
• Virginia Commonwealth UniversitycoreStrategic or Co-development PartnerContracting partner providing leadership in opioid overdose prevention. Works with TNP to educate hospital systems on distribution process and workflow of naloxone from emergency departments.
• Comagine HealthmajorStrategic or Co-development PartnerUtah chapter partner working to build relationships with key stakeholders statewide. Collaborating to implement sustainable, evidence-based strategies that empower healthcare providers to deliver lifesaving care.
• Tennessee Initiative for Perinatal Quality Improvement (TIPQC)majorStrategic or Co-development PartnerSupporting Tennessee chapter with program development and quality improvement initiatives for maternal overdose prevention.
• Colorado Hospital AssociationcoreChannel Partner/ Reseller/ DistributorKey Colorado partner supporting hospital enrollment in naloxone distribution programs. 107 hospital facilities enrolled through collaborative efforts representing 97% of state ED visits.
• Colorado Chapter, American College of Emergency Physicians (ACEP)coreStrategic or Co-development PartnerPartner organization providing clinical guidance and support for emergency department naloxone distribution programs. Logo displayed on partnership page.
• Montana Chapter, American College of Emergency PhysicianscoreStrategic or Co-development PartnerFounded Montana chapter in 2024 in partnership. Working to forge partnerships and recruit hospitals and EDs throughout Montana, with focus on rural and critical access facilities.
• Direct ReliefmajorStrategic or Co-development PartnerHumanitarian medical organization providing naloxone products and support for distribution programs.
• HarborPathmajorStrategic or Co-development PartnerPartner organization providing access to medications for underserved populations.
• Hikma PharmaceuticalsmajorStrategic or Co-development PartnerPharmaceutical partner supporting naloxone distribution and access initiatives.
• FFF EnterprisesmajorChannel Partner/ Reseller/ DistributorHealthcare distribution partner for naloxone products.
• TelligenmajorStrategic or Co-development PartnerHealthcare quality improvement organization supporting TNP programs in Colorado and other states.
• Colorado Consortium for Prescription Drug Abuse PreventioncoreStrategic or Co-development PartnerState consortium partner supporting prescription drug abuse prevention efforts through naloxone distribution. Board member Robert Valuck serves as Executive Director.
• Colorado Department of Regulatory AgenciesmajorStrategic or Co-development PartnerState agency partner supporting regulatory frameworks for naloxone distribution.
• Colorado Rural Health CentercoreStrategic or Co-development PartnerPartner supporting equitable access for rural and critical access hospitals. 30 rural facilities enrolled in Colorado program.
• Colorado Pharmacists SocietymajorStrategic or Co-development PartnerSupporting pharmacy-based naloxone access with 500+ pharmacies participating in Colorado.
• Harm Reduction Action CentermajorStrategic or Co-development PartnerCommunity harm reduction organization partner in Colorado.
• ACOG (American College of Obstetricians and Gynecologists)majorStrategic or Co-development PartnerNational medical organization partner supporting maternal overdose prevention and MOMs Initiative.
• American Academy of Pediatrics - Colorado ChaptermajorStrategic or Co-development PartnerSupporting pediatric-focused naloxone distribution and education.
• AWHONN Colorado (Association of Women's Health, Obstetric and Neonatal Nurses)majorStrategic or Co-development PartnerSupporting labor and delivery unit naloxone distribution through nursing professional partnership.
• Colorado Medical SocietymajorStrategic or Co-development PartnerState medical society partner supporting physician education and naloxone prescribing.
• Denver HealthcoreStrategic or Co-development PartnerMajor Denver healthcare system participating in and supporting naloxone distribution programs.
• OpiRescue / OpiSafemajorTechnology or IntegrationTechnology platform partner providing overdose response tools to care providers and first responders. Board member Robert Valuck is Co-founder and CEO.
• Massachusetts College of Emergency PhysicianscoreStrategic or Co-development PartnerState chapter partner working to ensure all EDs and facilities can dispense naloxone.
• Massachusetts Health and Hospital AssociationcoreChannel Partner/ Reseller/ DistributorState hospital association partner for Massachusetts chapter.
• Kentucky Hospital AssociationcoreChannel Partner/ Reseller/ DistributorState hospital association partner for Kentucky chapter working to provide naloxone to at-risk populations.
• Kentucky Bridge ProgrammajorStrategic or Co-development PartnerState program partner addressing substance use disorders.
• Kentucky State Opioid Stewardship ProgrammajorStrategic or Co-development PartnerState stewardship program partner.
• Washington Health Care Authority (HCA)coreStrategic or Co-development PartnerState agency that helped solve hospital reimbursement challenges. Leading implementation of State Bill 5195 mandating hospitals to identify at-risk individuals and dispense naloxone from EDs.
• Washington State Hospital Association (WSHA)coreChannel Partner/ Reseller/ DistributorState hospital association partner working with HCA and TNP to get naloxone to at-risk populations statewide.
• Wyoming Hospital AssociationcoreChannel Partner/ Reseller/ DistributorState hospital association partner for Wyoming chapter, working to change from dispensing model to distribution model.
• Wyoming ACEPcoreStrategic or Co-development PartnerState American College of Emergency Physicians chapter providing physician sponsorship for Wyoming programs.
• Missouri Hospital AssociationcoreChannel Partner/ Reseller/ DistributorState hospital association partner for Missouri chapter. VP of Substance Use Programming Shawn Billings serves as contact.

Scale indicators12 records

Recent moves18 records

Expansion highlights7 records

Direct peers

• Remedy Alliance / NEXT Distro: Nonprofit harm reduction supply distributors that provide free naloxone and drug-checking supplies to harm reduction programs nationwide. Most comparable as a national-scale naloxone distribution nonprofit operating through partner networks.
• National Harm Reduction Coalition: National nonprofit advocating for and providing harm reduction services including naloxone distribution to people who use drugs. Most directly comparable mission, scale (national), and constituency (people at risk of overdose).
• Harm Reduction Therapeutics: 501(c)(3) nonprofit that developed and distributes RiVive, a low-cost over-the-counter naloxone nasal spray. Directly comparable as a nonprofit naloxone access organization with a parallel mission to expand affordability and availability of the drug.

Broad incumbents

• Drug Policy Alliance: Major national advocacy organization that works on drug policy reform, including naloxone access and harm reduction. Operates at a broader policy level but shares TNP's mission of reducing overdose deaths through expanded access.
• Shatterproof: National nonprofit focused on ending addiction stigma and supporting people with substance use disorders. Broader mission than TNP but overlapping on opioid crisis response and policy advocacy.

Emerging players

• OpiSafe / OpiRescue: Technology platform for opioid patient management and overdose response, founded by Robert Valuck (TNP board member). Adjacent rather than directly competing, providing complementary digital tools that TNP's programs can use.
• Direct Relief: Major humanitarian medical aid organization that supplies naloxone and other medications to safety-net providers. Listed as a TNP partner but also operates independently as a much larger medical-supply distributor with overlapping naloxone programs.

Regional players

• Prevent Overdose RI / State-level Naloxone Coalitions: State-level overdose prevention coalitions that operate in geographies where TNP does not yet have chapters. Comparable in mission and chapter-based model but regional in scope rather than national.

Others

• American Medical Association (AMA): National physician organization that has partnered with TNP on naloxone access advocacy. Functions as an enabling partner/amplifier rather than direct competitor in naloxone distribution.
• Bicycle Health: Telehealth provider of medication-assisted treatment for opioid use disorder. Connected via TNP board member (Scott Weiner is Director of Research) but focused on treatment rather than overdose prevention/naloxone distribution.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/TheNaloxoneProject
• LinkedInlinkedin.com/company/naloxone-project

Revenue estimate

Valuation estimate

Number of profiles

Profiles13 records

Funding overview

Funding rounds

Investors

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about The Naloxone Project