Pearl

What Pearl does

Pearl (Pearl Inc.) is a privately held, Los Angeles-based dental artificial intelligence company founded in 2019 that builds FDA-cleared computer-vision software for dental radiograph analysis alongside a suite of adjacent clinical, administrative, and revenue-cycle AI products. The company's core technology is deep convolutional neural networks trained on what it describes as the world's largest dataset of dental radiographs (7+ million cases), annotated by world-renowned dentists and radiologists. Its flagship Second Opinion product performs real-time pathology detection on 2D dental X-rays (bitewing, periapical, panoramic) with up to 18 findings per image and an independently validated 94% accuracy. Second Opinion 3D extends the same architecture to cone beam computed tomography (CBCT), for which Pearl holds the only FDA 510(k) clearance for simultaneous 2D and 3D dental radiologic AI in the industry. The platform also includes Practice Intelligence (clinical and operational analytics surfacing ~$31,000/month per practice in uncovered treatment), Precheck (AI-powered insurance verification with 300+ insurer connections), Calibrate (clinical calibration and accreditation tooling), Pearl Voice (ambient AI for clinical documentation), and Pearl RCM (revenue cycle management), forming an end-to-end AI stack spanning diagnostic, clinical intelligence, administrative automation, and revenue operations.

Pearl operates a SaaS subscription model on quote-based enterprise pricing, monetizing primarily through recurring per-practice and per-DSO contracts combined with API/integration revenue via 40+ native OEM integrations across dental imaging and practice management platforms (Dentrix, Eaglesoft, Open Dental, Carestream, Romexis, Curve, Planet DDS, tab32, Patterson, Planmeca, among others). The go-to-market is dual-track: direct enterprise field sales targeting 100+ dental service organizations (DSOs) — including flagship accounts such as PDS Health (1,100+ practices), Smile Brands (600 locations), and DECA Dental (200 practices) — paired with embedded/OEM distribution through partner software platforms that deliver Pearl to a 29,000+ practice long-tail across 120+ countries. Secondary segments include dental universities (UNC, UCLA, UPenn, MUSC, University of Pittsburgh, Columbia, UNMC, Pacific, ECU) for educational and accreditation use cases, and individual SMB practices acquired via website demo requests. The company is venture-backed, having raised a $58 million Series B in July 2024 led by Left Lane Capital (the largest investment in dental AI at the time) following a strategic investment from Dental Innovation Alliance. Pearl holds 26+ regulatory clearances including FDA 510(k), EU MDR, ISO 13485, MDSAP, and SOC 2 Type II compliance, with HIPAA and GDPR alignment for data handling.

Name

Pearl

Legal name

Pearl Inc.

Website

https://hellopearl.com

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

101–250 employees

Short description

Pearl is a dental AI company providing FDA-cleared 2D and 3D radiograph analysis, insurance verification, clinical analytics, and revenue cycle management to 29,000+ practices and 100+ DSOs across 120+ countries.

Ownership category

akta.pro rank

Product category

Dental AI Software

NAICS

Software Publishers (5132), Software Publishers (513210)

SIC

Services-Prepackaged Software (7372), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Software as a Medical Device (SaMD) – Clinical Decision & Diagnostic Software (HLACANAD)

akta.pro secondary industries

SaMD – Imaging & Signal Analysis (AI/ML) (HLACANAG), Dental Imaging Interpretation & Teleradiology Services (HLABAIAK), Medical Imaging AI (HDAAAEAH)

Keywords

• Dental artificial intelligence
• Radiologic pathology detection
• Practice management analytics
• Insurance verification software
• CBCT imaging analysis

Headquarters

HQ city

West Hollywood

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. SaaS Subscriptions for Dental AI Software: Pearl operates on a recurring SaaS subscription model, charging dental practices and DSOs for access to its AI-powered software suite (Second Opinion, Practice Intelligence, Precheck, Voice, Calibrate, RCM). Pricing is likely per-practice or per-seat, with enterprise pricing for multi-location DSOs. The company targets both individual dental practices (SMB/mid-market) and large dental service organizations (enterprise) through sales-assisted subscriptions.
2. Platform and API Integration Fees: Pearl generates revenue through integrations with 40+ dental imaging and practice management platforms (Open Dental, Dentrix, Eaglesoft, Carestream, Curve, Romexis, etc.), potentially through API access fees, platform partnership agreements, or co-distribution revenue share arrangements embedded in the dental software ecosystem.

Pricing tiers

Go-to-market motion3 records

Distribution channels5 records

Marketing channels8 records

Core offering

Pearl sells FDA-cleared dental AI software that automatically detects pathologies on dental X-rays and CBCT scans and powers practice analytics, insurance verification, clinical documentation, and revenue cycle management for dental practices, dental service organizations, and dental schools. Its products are delivered primarily as cloud-hosted, subscription-based AI embedded within existing dental imaging and practice management workflows.

Product overview

Pearl offers a unified platform of AI-powered dental solutions comprising seven core products: Second Opinion (FDA-cleared AI for real-time 2D X-ray pathology detection), Second Opinion 3D (AI for 3D CBCT imaging analysis - the first dental AI with clearance for both 2D and 3D), Practice Intelligence (clinical performance and practice optimization analytics), Precheck (instant AI-powered insurance verification), Pearl RCM (revenue cycle management with embedded insurance intelligence), Calibrate (AI-powered clinical training and calibration), and Pearl Voice (ambient voice AI for clinical documentation). The platform serves 29,000+ dental practices across 120+ countries, integrates natively with 40+ imaging and practice management systems, and holds 26+ regulatory clearances including FDA, Health Canada, TGA, and EU MDR. The architecture is designed as a modular platform where Second Opinion and Practice Intelligence serve as the core clinical AI engine, with Precheck and RCM adding revenue cycle capabilities, Calibrate enabling enterprise training, and Voice adding ambient documentation.

Differentiator

Problem solved

Functional benefit

Brands

• Second Opinion: FDA-cleared AI for real-time pathology detection on 2D dental X-rays
• Second Opinion 3D
• Practice Intelligence
• Precheck
• Calibrate
• Voice
• RCM

Products and services

• Second Opinion FDA-cleared AI that automatically analyzes 2D dental radiographs (bitewing, periapical, panoramic) and highlights up to 18 findings per image, including caries, bone loss, calculus, periapical radiolucencies, defective restoration margins, and impactions, with 94% independently validated accuracy. Used by dentists, DSOs, and dental schools for diagnostic support and patient communication.
• Second Opinion 3D FDA-cleared AI for automated identification of key anatomical structures and pathology detection in 3D CBCT dental scans. The first and only dental AI with FDA clearance for simultaneous 2D and 3D radiologic analysis, supporting diagnostics and treatment planning across implantology, orthodontics, and oral surgery.
• Practice Intelligence AI-powered clinical performance and practice optimization platform that pairs radiologic AI with practice data to deliver insights on clinical quality, financial performance, appointment compliance, case acceptance, and per-provider production. Surfaces specific treatment opportunities, powers Morning Huddle reports, and enables AI-guided daily schedules.
• Precheck AI-powered dental insurance verification tool that automatically confirms benefits for scheduled patients up to 14 days in advance, with real-time eligibility results in under 10 seconds for 80%+ of checks. Provides tooth-specific treatment and benefits history and saves practices 20+ hours per week on administrative work.
• Pearl RCM Revenue cycle management platform that embeds insurance intelligence throughout the dental workflow, including eligibility verification, FDA-cleared radiologic AI for real-time x-ray quality assessment, and automated image selection for claims. Early adopters save up to 35 staff hours per week and reduce claim denials by up to 80%.
• Calibrate AI-powered clinical calibration and team training platform for dental organizations and universities that allows leadership to define diagnostic standards, benchmark providers and students against expert criteria, surface specific improvement areas, and document calibration for CODA-aligned accreditation.
• Pearl Voice Ambient voice AI for clinical notes and periodontal charting that supports hands-free voice perio charting and automated SOAP note generation, saving providers 60+ minutes per day on documentation.

Quantifiable outcome

• 37% more disease detected on average by practices using Pearl
• +16 more outcomes

Named customers28 records

Segments5 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration26 records

AI capability9 records

Feature8 records

Partnerships

14 partnerships are on record, tiered core, flagship and supporting.

• ClearDentcoreTechnology or Integration · 18 June 2026Pearl partnered with ClearDent (dental practice management platform founded in Burnaby, Canada in 2002) to integrate Pearl's Second Opinion chairside radiologic dental AI disease detection software with ClearDent's imaging toolset via API. The partnership enables Canadian dental practitioners to access AI-powered pathology detection (caries, calculus, periapical radiolucency) through ClearDent's Developer Program. Joint educational initiatives, webinars, and events planned to advance AI adoption in Canadian clinical practice. Pearl's Second Opinion has regulatory clearance in Canada, USA, Australia, New Zealand, and Europe.
• Smile BrandsflagshipChannel Partner/ Reseller/ Distributor · 15 June 2026Smile Brands (one of the largest U.S. providers of dental support services with 600 locations across 80 brands) selected Pearl as its exclusive dental AI partner following a rigorous multi-vendor evaluation. Completed an initial pilot demonstrating measurable improvements in clinician diagnosis presentations and an increase in same-day treatment acceptance rates. Rollout has begun to a significant number of offices with the goal of full deployment across Smile Brands' entire network.
• ADEA (American Dental Education Association)supportingStrategic or Co-development Partner · 25 April 2026Pearl's AI Calibration Tool implementation at UCLA School of Dentistry was supported by an ADEA (American Dental Education Association) grant, demonstrating a strategic alignment with dental education standards and accreditation bodies.
• RipeGlobalsupportingGTM or Marketing Partner · 2 April 2026Pearl partnered with education platform RipeGlobal to provide training programs for dental professionals on implementing AI in their practices. The partnership grants new and existing Pearl subscribers access to RipeGlobal's cloud-based platform for six months, offering on-demand courses, live workshops, and community learning focused on AI literacy, adoption strategies, and practice performance outcomes.
• DECA Dental GroupflagshipChannel Partner/ Reseller/ Distributor · 24 February 2026DECA Dental Group selected Pearl as its exclusive dental AI partner following a successful pilot study that demonstrated measurable improvements in case acceptance rates through AI-visualized radiographs and generated early ROI. DECA deployed Pearl across its nearly 200 practices spanning nine U.S. states. Integration is directly into DECA's existing practice management software for real-time clinical insights and enterprise-wide visibility.
• Coast DentalflagshipChannel Partner/ Reseller/ Distributor · 11 February 2026Coast Dental implemented Pearl's FDA-cleared AI platform across its 88-practice network as part of a broader DSO AI adoption strategy. Coast Dental is one of several DSOs investing in Pearl alongside PDS Health and others.
• PDS HealthflagshipChannel Partner/ Reseller/ Distributor · 4 February 2026PDS Health (integrated healthcare support organization operating dental practices) selected Pearl as its enterprise AI partner to deploy real-time radiologic review and clinical intelligence tools across its network of more than 1,100 dental practices nationwide. Pearl's FDA-cleared AI platform is integrated into existing imaging workflows for chairside image review, visual indicators, and practice-level reporting across both traditional radiographic imaging and CBCT workflows.
• Curve DentalcoreTechnology or Integration · 19 August 2025Pearl expanded its AI integration with Curve Dental to include Practice Intelligence alongside existing Second Opinion integration. Curve Dental is a cloud-based dental practice management platform. The expanded API integration allows Curve users to access Pearl's AI-powered analytics directly within their workflow. Pearl also integrated via Curve Dental's Developer Program for distribution to Canadian dental practices.
• UCLA School of DentistrysupportingStrategic or Co-development Partner · 27 May 2025UCLA School of Dentistry partnered with Pearl to implement Pearl's AI Calibration Tool with support from an ADEA grant. This partnership advances AI integration in dental education and supports student diagnostic training, faculty calibration, and CODA accreditation standards.
• Planet DDScoreTechnology or Integration · 24 July 2024Planet DDS partnered with Pearl as part of its comprehensive and open API program for DSOs and dental partners. Pearl's AI solutions are integrated into Planet DDS's DentalOS platform (Denticon, Cloud 9, Apteryx, Legwork) to deliver integrated AI-powered clinical and administrative tools. Planet DDS serves over 13,000 dental practices.
• Patterson DentalcoreChannel Partner/ Reseller/ Distributor · 22 July 2024Pearl collaborated with Patterson Dental to advance dental AI. Patterson Dental is a major U.S. dental distributor and technology provider. A separate Canada-specific partnership was announced with Patterson Dental Canada in July 2024 to advance dental AI in Canadian dentistry.
• ArchycoreTechnology or Integration · 17 July 2024Pearl and Archy announced an integration partnership for dental artificial intelligence. Archy is a dental practice management platform. The integration embeds Pearl's AI capabilities into Archy's platform for joint customers.
• tab32supportingTechnology or Integration · 8 July 2024tab32 (cloud-based dental practice management platform) partnered with Pearl to integrate Pearl's AI capabilities into its platform, upgrading tab32's offering with AI-powered clinical and administrative tools for dental practices.
• PlanmecacoreTechnology or Integration · 1 April 2023Planmeca Oy partnered with Pearl in April 2023 to integrate Pearl's FDA-cleared AI algorithms into Planmeca's CBCT imaging workflows. This integration embeds Pearl's radiologic AI capabilities directly into Planmeca's dental imaging hardware and software ecosystem for enhanced diagnostic analysis.

Scale indicators8 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Overjet: Overjet is a US-based AI platform that provides FDA-cleared dental imaging AI for pathology detection and dental-insurance claims analysis, serving DSOs and insurance payers—the closest direct competitor to Pearl in dental diagnostic AI.
• Diagnocat: Diagnocat is a dental imaging AI company offering 2D and 3D CBCT radiograph analysis and pathology detection for dentists and DSOs globally, overlapping directly with Pearl's Second Opinion and Second Opinion 3D product lines.
• VideaHealth: VideaHealth develops FDA-cleared dental imaging AI for caries and other pathology detection on dental X-rays, targeting DSOs and dental practices—directly competing with Pearl's Second Opinion capabilities.

Others

• Curve Dental: Curve Dental is a cloud-based dental practice management platform and a Pearl integration partner via its Developer Program—adjacent rather than competitive, but a stakeholder in the dental software ecosystem where Pearl distributes.
• Planmeca: Planmeca is a global dental imaging hardware and software OEM (Romexis platform) that in 2023 integrated Pearl's FDA-cleared AI directly into its dental imaging workflows—supplier/partner with potential to expand into broader AI offerings.

Broad incumbents

• Patterson Dental: Patterson Dental is a major US dental distributor and technology provider (Eaglesoft, etc.) that has partnered with Pearl to advance dental AI—broad incumbent with distribution scale that enables or threatens Pearl's go-to-market depending on strategic direction.
• 3Shape: 3Shape is a global dental technology company specializing in 3D scanning, CAD/CAM, and practice management software for dentists and labs—broad incumbent whose imaging and software ecosystem overlaps with Pearl's clinical AI distribution surface.
• Planet DDS: Planet DDS is a cloud dental software provider (Denticon, Cloud 9, Apteryx, Legwork) serving 13,000+ practices via an open API program that includes Pearl—broader incumbent with reach Pearl leverages for distribution, but with potential to bundle competing AI.
• Henry Schein One: Henry Schein One is a large dental software and technology provider offering practice management, imaging, and patient-communication tools to dental practices—broad incumbent whose platforms Pearl integrates with and that could build competing AI capabilities.

Emerging players

• Denti.AI: Denti.AI develops AI for dental imaging analysis (charting, pathology, and voice-enabled clinical notes), targeting dental practices and software platforms with niche overlap to Pearl's diagnostic and Pearl Voice products.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/pearlincai
• Facebookfacebook.com/pearlartificialintelligence
• LinkedInlinkedin.com/company/hellopearl
• Instagraminstagram.com/pearl.ai

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Funding overview

Funding rounds4 records

Investors9 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pearl