Kno2

What Kno2 does

Kno2 operates a healthcare communication network that delivers clinical information exchange across the U.S. healthcare ecosystem through a single API and an adjacent web-based portal (Kno2fy). The company's core product is the Kno2 Communication API, a REST-based interface providing Send, Receive, and Find routes that normalize access to fax, Direct Secure Messaging, FHIR, HL7 V2.x, Carequality, TEFCA via its QHIN designation, and 20+ HIEs. Complementing the API is the Kno2fy Portal, a HIPAA-compliant web interface consolidating cloud fax, Direct messaging, EHR integration, referral workflows, and e-signature into a single subscription. Feature surface also includes Track the Fax barcode reconciliation, the content-agnostic FHIR model, the provider communication directory, the CAREplan clinical communication workflow product, and the recently announced CLEAR1 core network infrastructure rollout (January 2026).

Kno2 serves four primary customer segments: healthcare providers (acute, post-acute, home health, behavioral health, specialty practices), technology vendors (EHRs, digital health platforms, RPM companies), payers (the first being Clover Health live on a CMS Aligned Network and TEFCA in March 2026), and value-based care organizations. Distribution combines direct enterprise sales, a self-service developer portal, a Connected Partner Program (EHRs, RPM, digital health, office technology OEMs such as Konica Minolta and Xerox), and a strategic alliance with Redox that together reach nearly 160,000 provider organizations representing 75% of U.S. health systems. Notable enterprise logos include PointClickCare, The Pennant Group, Symphony Care Network, Carilion Clinic, and Zus Health, alongside EHR integrations with Epic, Oracle Health, and CommonWell. Compliance posture includes HITRUST r2 certification on the Kno2fy Platform and SOC 2 Type II certification.

Revenue is generated primarily through recurring API subscriptions to the communication network and Kno2fy portal subscriptions, with enterprise add-ons (SSO, bulk uploads, enterprise APIs, private label, volume tools). Pricing is quote-based and not publicly disclosed; the company positions its "connect once" economic model against the alternative of building separate integrations to each network. The firm is privately held (Idaho LLC, Boise HQ with a Scottsdale office), backed by HEP and Providence Ventures following a $15 million Series A in 2023, and employs 11–50 people. Founded in Boise in 2012, Kno2 has expanded from document exchange to a federally designated QHIN under TEFCA and a pledged CMS Aligned Network.

Name

Kno2

Legal name

Kno2 LLC

Website

https://kno2.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

Kno2 operates the nation's largest healthcare communication network, delivering a single API and the Kno2fy portal that enable providers, payers, EHR vendors, and technology platforms to exchange patient information across TEFCA, Carequality, Direct, FHIR, HL7, and fax frameworks.

Ownership category

akta.pro rank

Product category

Healthcare Interoperability Platform

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518), Computer Systems Design and Related Services (54151)

akta.pro primary industry

Remote Patient Monitoring (RPM) Platforms & Device Hubs (Connectivity/Gateways) (HLAHACAH)

Keywords

• Healthcare interoperability platform
• Clinical information exchange
• Health information network
• FHIR API integration
• Electronic fax healthcare

Headquarters

HQ city

Boise

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Communication API Subscription: Kno2 generates revenue through API subscription fees where technology vendors, EHRs, and healthcare organizations pay for access to the communication network. The company states it offers disruptive, affordable economics where partners pay for one connection but gain access to all networks and interoperability frameworks. Pricing is provided as a single connection point to the combined network's full reach.
2. Kno2fy Portal Subscription: The Kno2fy web-based portal is offered as a single subscription model that centralizes all patient information sharing and communications. This includes cloud faxing, Direct messaging, EHR integration, referral workflows, and other communication capabilities.
3. Enterprise Features: Large enterprise customers can access additional features including single sign-on, bulk uploads, Enterprise APIs, private label options, volume-based file handling tools, and centralized shared service functions.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels8 records

Core offering

Kno2 develops and operates a full-stack healthcare communication network that provides a single Communication API and the Kno2fy Portal for clinical information exchange. The platform enables healthcare providers, payers, EHRs, and health IT companies to send, receive, and find patient information across fax, Direct Secure Messaging, FHIR, HL7 V2.x, Carequality, and TEFCA/QHIN networks through one integration.

Product overview

Kno2 is a full-stack healthcare communication network providing a unified platform for clinical information exchange across the healthcare ecosystem. The core offering consists of two access methods: the Kno2 Communication API (for technology vendors and organizations requiring programmatic integration) and the Kno2fy Communication Portal (for organizations needing web-based access). These are supported by multiple connectivity features including Carequality network integration, cloud fax, Direct Secure Messaging, electronic signing, HIE connectivity, HL7 FHIR, HL7 V2.x, referral networks with 360X protocol, and TEFCA/QHIN services. The platform processes billions of transactions annually, connecting over 100,000 provider organizations across acute, post-acute, and specialty care settings.

Differentiator

Problem solved

Functional benefit

Brands

• Kno2fy: Kno2's turnkey, web-based HIPAA-compliant communication portal that centralizes and manages all major forms of patient information sharing and communications in a single subscription.

Products and services

• Kno2 Communication API A REST-based Communication API that enables technology vendors, EHRs, payers, and healthcare organizations to send, receive, and find clinical information across the entire healthcare ecosystem through a single integration to TEFCA, Carequality, Direct Secure Messaging, FHIR, HL7 V2.x, cloud fax, and HIE networks.
• Kno2fy Communication Portal A turnkey, web-based HIPAA-compliant communication portal that centralizes and manages all major forms of patient information sharing including cloud faxing, Direct messaging, EHR integration, provider directories, auditing, reporting, and customizable referral workflows in a single subscription.
• QHIN Services (TEFCA) Qualified Health Information Network services under TEFCA enabling nationwide health information exchange, including access to federal health information networks and CMS Aligned Network capabilities. QHIN services are integrated into the Communication API and can be white-labeled for partners.

Quantifiable outcome

• Multi-million dollar ROI for healthcare systems modernizing electronic faxing workflows
• +2 more outcomes

Named customers10 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration6 records

Feature10 records

Partnerships

21 partnerships are on record, tiered flagship, core and standard.

• CareQuest Innovation PartnersflagshipStrategic or Co-development Partner · 26 March 2026Strategic partnership to integrate dental care into the nation's health information exchange infrastructure. Two leading electronic dental record platforms representing approximately 20% of the dental market have committed as flagship partners. Goal is production go-live within six months and 25% adoption among participating EDR provider users in the first year. Enables bidirectional data exchange between medical and dental providers for improved care coordination, patient safety, and health equity.
• Clover HealthcoreTechnology or Integration · 4 March 2026Clover Health became the first payer to go live on a CMS Aligned Network and TEFCA through collaboration with Kno2. Enables real-time patient access to claims and clinical data using standardized FHIR (USCDI v3) formats. Powered by Counterpart Health's infrastructure, allowing patients to securely authenticate and request health information from any participating payer through Kno2's connected network.
• OliostandardTechnology or Integration · 27 February 2026Behavioral health coordination company Olio partnered with Kno2 to integrate real-time EHR access into its platform, streamlining care coordination for patients moving between healthcare settings.
• FlexpastandardTechnology or Integration · 6 January 2026Partnership combines patient-authorized data aggregation with Kno2's nationwide QHIN infrastructure to improve care coordination. Patients can more easily access and share their health data across the healthcare ecosystem.
• RXNTcoreTechnology or Integration · 18 December 2025RXNT announced TEFCA connectivity and integrated QHIN access through strategic partnership with Kno2. The integration connects RXNT's customers to over 10,000 organizations with planned availability in 2026. Enables nationwide interoperability for healthcare data exchange.
• Greenlight Health Data SolutionscoreTechnology or Integration · 16 December 2025Expanded partnership with Kno2 to enhance national healthcare data interoperability through TEFCA. Collaboration aims to support secure, patient-mediated health data exchange and expand TEFCA-enabled connectivity in the healthcare industry.
• Health UniversestandardTechnology or Integration · 16 December 2025Partnership to provide instant medical record retrieval and AI-driven clinical insights to healthcare providers nationwide. Collaboration enables real-time access and transformation of patient records into actionable insights for clinics, hospitals, and health systems.
• Net HealthcoreStrategic or Co-development Partner · 12 November 2025Expanded strategic partnership with Net Health (active since 2021) to enhance healthcare data exchange capabilities across various care settings. Partnership aims to improve interoperability, reduce reliance on fax workflows, and support compliance with federal regulations.
• RedoxflagshipStrategic or Co-development Partner · 16 October 2025Strategic alliance to transform healthcare data exchange nationwide. Combined network transacts over 40 billion annual transactions and connects nearly 160,000 provider organizations representing 75% of health systems and 80% of providers from non-acute settings. The partnership provides unified integration through a single connection point with scalable architecture for bi-directional data flow and universal data translation to HL7v2, FHIR, X12, CDA, and proprietary formats.
• NextGen HealthcarecoreTechnology or Integration · 25 September 2025Partnership to advance interoperability for healthcare organizations across the US. Integration enables more than 100,000 providers representing a wide range of specialties to participate in TEFCA through NextGen's partnership with Kno2. Positions both companies to expand reach within the healthcare IT ecosystem while enabling frictionless, secure data flow across providers, payers, and patients.
• Zus HealthcoreTechnology or IntegrationZus Health partnership making Kno2 their official QHIN partner to enhance healthcare data exchange and interoperability. Collaboration aims to improve health data sharing, patient outcomes, and support implementation of TEFCA frameworks. Kno2's APIs provide configurability and performance needed for Carequality and TEFCA connectivity.
• EpiccoreTechnology or IntegrationEpic is listed as a participant in Kno2's network ecosystem, enabling data exchange through Carequality and interoperability frameworks.
• Oracle HealthcoreTechnology or IntegrationOracle Health is listed as a participant in CMS interoperability initiatives and Kno2's network ecosystem.
• CommonWell Health AlliancecoreTechnology or IntegrationCommonWell is part of Kno2's national network connectivity, enabling health data exchange across member organizations.
• PointClickCarecoreTechnology or IntegrationSenior care EHR platform partnered with Kno2 for value-based care data exchange, increasing care coordination, closing gaps in care, and reducing readmission risks.
• DocuSigncoreTechnology or IntegrationDocuSign is integrated with Kno2 for electronic signing workflows, enabling documents to be delivered for signature to any Kno2 Connected platform or EHR.
• Konica MinoltastandardTechnology or IntegrationKonica Minolta devices are Kno2 Connected, enabling multi-function printers to integrate with Kno2's communication network.
• XeroxstandardTechnology or IntegrationXerox devices are Kno2 Connected, enabling office equipment to integrate with Kno2's healthcare communication network.
• WellSkycoreTechnology or IntegrationWellSky is a Kno2 Connected partner providing post-acute care technology solutions with interoperability capabilities.
• AxxesscoreTechnology or IntegrationAxxess is a Kno2 Connected partner for home health technology solutions.
• MuleSoft / SalesforcecoreTechnology or IntegrationKno2 offers a MuleSoft Connector enabling integration with Salesforce ecosystem and enterprise workflow automation.

Scale indicators8 records

Recent moves7 records

Expansion highlights9 records

Market position

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/kno2
• YouTubeyoutube.com/channel/UC7NRzQWyijaAjzzd34q5Ylg
• LinkedInlinkedin.com/company/kno2
• Facebookfacebook.com/getkno2

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles12 records

Funding overview

Funding rounds3 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Kno2