GreenMark Biomedical
- Company typePrivate
- Founded2016
- HeadquartersEast Lansing, United States
- Headcount11–50
- GTM typeB2B and B2C
- OfferingHardware or Manufacturing
GreenMark Biomedical firmographics
Firmographics- Name
- GreenMark Biomedical
- Legal name
- GreenMark Biomedical Inc.
- Website
- https://greenmark.bio
- Company type
- Private
- Founded year
- 2016
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Ownership category
- akta.pro rank
GreenMark Biomedical industry classification
Industry- Product category
- Preventive Dental Products
- NAICS
- Dental Equipment and Supplies Manufacturing (339114), Research and Development in Nanotechnology (541713)
- SIC
- Dental Equipment & Supplies (3843), Surgical & Medical Instruments & Apparatus (3841), In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Preventive & Routine General Dentistry (Exams/Cleanings/Sealants/Fluoride) (HLABAAAA)
- akta.pro secondary industries
- Desensitization Treatments for Dentin Hypersensitivity (HLABAHAK), Oral Care Products (Toothpaste, Mouthwash, Dental Floss, Whitening) (CRADAMAA)
Keywords
Where GreenMark Biomedical is headquartered
LocationHeadquarters
- HQ city
- East Lansing
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
GreenMark Biomedical business model
Business model- GTM type
- B2B and B2C
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Supply Chain, Marketing or Sales, Operations, Infrastructure
Revenue model
- CrystLCare™ Biorestorative Dental Strips: Sale of CrystLCare™ Biorestorative fluoride-free dental strips for in-office and at-home treatment of dental hypersensitivity and enamel remineralization. Products are sold directly to dental professionals (for in-office application) and through consumer channels (Great Oral Health, Dentulu). CrystLCare™ PRO Biorestorative Fluoride-Plus received FDA 510(k) clearance in January 2025.
- LumiCare™ and LumiKids™ Caries Detection Rinse: Sale of fluorescent starch nanoparticle-based caries detection rinses for dental professionals. LumiCare™ (20 pouches/box, $299.99) and LumiKids™ (25 pouches/box, $249.99) are used during routine dental exams to illuminate early-stage carious lesions. FDA-cleared 510(k) Class II medical devices.
- Future Regenerative Dental Consumer Products: GreenMark is developing additional regenerative dental products including toothpaste tablets, chewing gums, and edible formulations using mineral-loaded starch nanoparticles, targeting the consumer oral care market as well as professional dental applications.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | LumiCare™ Caries Detection Rinse — Professional Box |
| Unit Pricing | Pay-as-you-go | LumiKids™ Caries Detection Rinse — Professional Box |
| Unit Pricing | Pay-as-you-go | CrystLCare™ Biorestorative Fluoride-Free — At-Home Treatment Strips |
Go-to-market motion3 records
Distribution channels3 records
Marketing channels9 records
GreenMark Biomedical product offering
Product offeringCore offering
GreenMark Biomedical develops and sells dental products based on a proprietary bioresorbable starch nanoparticle platform. Its commercial offerings include LumiCare and LumiKids Caries Detection Rinses (fluorescent nanoparticle rinses used during dental exams to illuminate early-stage cavities under a standard dental curing light) and the CrystLCare Biorestorative line of fluoride-free and fluoride-plus dental strips that release calcium and phosphate in the mouth to form hydroxyapatite, occluding exposed dentinal tubules for sensitivity relief and enamel remineralization.
Product overview
GreenMark Biomedical develops a systems-based approach to dental caries management using a proprietary platform of functionalized starch nanoparticles. The product portfolio includes LumiCare and LumiKids Caries Detection Rinses (FDA-cleared 510(k) Class II Medical Devices) for early-stage caries identification using fluorescent nanoparticle technology, and CrystLCare Biorestorative products (Fluoride-Free and Fluoride-Plus variants) for treatment of dental sensitivity and enamel remineralization. The platform technology enables both diagnostic detection (illuminating lesions under dental curing light) and therapeutic delivery (targeting minerals to tooth subsurface) through the same core nanoparticle carrier system.
Differentiator
Problem solved
Functional benefit
Brands
- CrystLCare™: CrystLCare™ Biorestorative product line including Fluoride-Free and Fluoride-Plus dental strips for dental sensitivity relief and enamel restoration using mineral-loaded starch particles.
- LumiCare™
- LumiKids™
Products and services
- CrystLCare Biorestorative, Fluoride-Free Fluoride-free dissolvable dental strips containing mineral-loaded starch nanoparticles that release calcium and phosphate in the mouth, forming hydroxyapatite crystals to occlude exposed dentinal tubules and fill enamel porosities for immediate and long-lasting dental sensitivity relief and enamel remineralization. First treatment applied in-office, with continued at-home use. Sold in 14- and 28-unit fliptop packs.
- CrystLCare PRO Biorestorative, Fluoride-Plus Advanced fluoride-containing version of the CrystLCare Biorestorative dental strip product line, combining mineral-loaded starch nanoparticle technology with fluoride for dental sensitivity relief and enamel restoration. FDA 510(k) Class II Medical Device.
- LumiCare Caries Detection Rinse Water-based dental rinse containing fluorescent sub-micron starch nanoparticles functionalized to target and adhere to the subsurface of early-stage carious lesions. Used during routine dental exams to illuminate otherwise undetectable early cavities when viewed under a standard dental curing light. Sold in boxes of 20 single-use pouches at $299.99 per box. FDA 510(k) Class II Medical Device; Cellerant Best of Class Technology Award winner in 2020 and 2021.
- LumiKids Caries Detection Rinse Pediatric dental rinse containing half-dose fluorescent sub-micron starch nanoparticles that target and illuminate early-stage carious lesions under a dental curing light during routine dental exams. Designed for children ages 6-12. Sold in boxes of 25 single-use 10 mL pouches at $249.99 per box. FDA 510(k) Class II Medical Device.
Companies that use GreenMark Biomedical
Customer profileNamed customers6 records
Segments2 records
Ideal customer profiles2 records
GreenMark Biomedical technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability1 record
Feature5 records
GreenMark Biomedical partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core.
- Great Oral HealthcoreGreat Oral Health, a direct-to-consumer oral health company, adopted CrystLCare™ Biorestorative Fluoride-Free dental strips into its product line to help combat dental sensitivity and strengthen enamel. Products are available for purchase through Great Oral Health's e-commerce platform (greatoralhealth.com).
- Dentulu, Inc.coreGreenMark announced a strategic partnership with Dentulu, the largest online dental service provider in the US, to introduce CrystLCare™ Biorestorative in a GreenMark-Dentulu co-branded product line. This partnership provides access to Dentulu's nationwide network of dental professionals and their e-commerce platform for both B2B (Dentulu Pro) and direct-to-consumer sales. Dentulu's teledentistry platform also enables broader reach for GreenMark's non-invasive dental products.
- University of MichigancoreGreenMark's core starch nanoparticle technology was developed in collaboration with researchers at the University of Michigan, including Prof. Joerg Lahann (Department of Chemical Engineering, Materials Science and Engineering, and Biomedical Engineering; Director of the UM Biointerfaces Institute) and Prof. Brian Clarkson (Department of Cariology, Restorative Sciences and Endodontics). The collaboration has resulted in multiple co-invented patents and ongoing NIH-funded research projects.
- EcoSynthetix Inc. (TSX: ECO)coreEcoSynthetix Inc., co-founded by GreenMark's CEO Steven Bloembergen, is the supplier of starch nanoparticles for GreenMark's dental technology. GreenMark also produces its own starch microparticles for the CrystLCare™ product line. EcoSynthetix is a publicly traded company on the TSX (TSX: ECO).
Scale indicators14 records
Recent moves6 records
Expansion highlights6 records
GreenMark Biomedical competitors and assessment
Company assessmentDirect peers
- Quantum Dental Technologies: Developer of the Canary System, a laser-based caries detection device used by dental professionals. Directly comparable to GreenMark's LumiCare in the caries detection category, addressing the same early-lesion identification use case in dental offices.
- SDI Limited: Australian dental materials manufacturer offering remineralization and desensitization products (e.g., Riva Star, Tooth Mousse). Comparable to GreenMark's CrystLCare biorestorative product line for enamel repair and sensitivity relief in dental practices.
- VOCO GmbH: German dental materials manufacturer producing remineralization, desensitization, and preventive care products (e.g., Remin Pro, Profluorid). Comparable to GreenMark's CrystLCare as a focused dental materials company serving caries prevention and sensitivity management.
- Premier Dental: US-based manufacturer of preventive dental products including desensitizers, fluoride treatments, and diagnostic materials. Comparable to GreenMark in the preventive dental product category, addressing similar professional-use cases for caries management and sensitivity relief.
Emerging players
- Pearl: AI-powered dental diagnostic platform that analyzes intraoral images for caries, restorations, and other conditions. Directly comparable to GreenMark's AI-enabled intraoral imaging initiative, targeting the same computer-vision-driven caries detection use case.
- Overjet: AI dental imaging and clinical decision support platform approved by the FDA for caries detection and other diagnostics. Comparable to GreenMark's emerging AI-enabled intraoral imaging initiative, targeting the same computer-vision-based caries detection and monitoring workflow in dental practices.
Broad incumbents
- KaVo Dental (Envista): Established dental equipment manufacturer offering DIAGNOdent, a laser-based caries detection device, as part of a broader dental equipment portfolio. Comparable to GreenMark's LumiCare in caries detection but competing as part of a much larger product catalog.
- Colgate-Palmolive: Global consumer oral care leader with sensitivity and anticaries product lines (e.g., Colgate Sensitive, Colgate Total). Comparable to GreenMark's planned consumer oral care expansion into toothpaste tablets and related products, though Colgate operates at vastly larger scale across broader categories.
- GlaxoSmithKline (Sensodyne): Owner of the Sensodyne brand, the dominant over-the-counter dental hypersensitivity treatment line globally. Comparable to GreenMark's CrystLCare in the dental sensitivity category, though GSK operates as a broad consumer health incumbent with extensive distribution and marketing.
- Dentsply Sirona: Largest global manufacturer of professional dental equipment, instruments, and consumables, including caries detection and restorative materials. Comparable to GreenMark as a competitor in professional dental markets but operating across a vastly broader product portfolio.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
GreenMark Biomedical social profiles
Digital presenceGreenMark Biomedical financial estimates
Financial estimateRevenue estimate
Valuation estimate
GreenMark Biomedical leadership team
Management profileNumber of profiles
Profiles4 records
GreenMark Biomedical funding detail
Funding detailFunding overview
Funding rounds9 records
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
GreenMark Biomedical M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about GreenMark Biomedical
What does GreenMark Biomedical do?
GreenMark Biomedical develops and sells dental products based on a proprietary bioresorbable starch nanoparticle platform. Its commercial offerings include LumiCare and LumiKids Caries Detection Rinses (fluorescent nanoparticle rinses used during dental exams to illuminate early-stage cavities under a standard dental curing light) and the CrystLCare Biorestorative line of fluoride-free and fluoride-plus dental strips that release calcium and phosphate in the mouth to form hydroxyapatite, occluding exposed dentinal tubules for sensitivity relief and enamel remineralization.
Is GreenMark Biomedical a public or private company?
GreenMark Biomedical is a private company. It is classified as venture growth investor backed and is currently operating.
When was GreenMark Biomedical founded?
GreenMark Biomedical was founded in 2016. It employs 11 to 50 people.
Where is GreenMark Biomedical based?
GreenMark Biomedical is headquartered in East Lansing, United States, in the North America region.
How does GreenMark Biomedical make money?
Three revenue lines are on record. CrystLCare™ Biorestorative Dental Strips are the primary driver. The others are lumiCare™ and LumiKids™ Caries Detection Rinse and future Regenerative Dental Consumer Products.
Who are GreenMark Biomedical's main competitors?
Direct peers on record are Quantum Dental Technologies, SDI Limited, VOCO GmbH and Premier Dental. Emerging players are Pearl and Overjet. Broad incumbents are KaVo Dental (Envista), Colgate-Palmolive, GlaxoSmithKline (Sensodyne) and Dentsply Sirona.
Does GreenMark Biomedical have an API?
No public API is recorded for GreenMark Biomedical.
What industry is GreenMark Biomedical in?
GreenMark Biomedical's product category is Preventive Dental Products. Its primary akta.pro industry code is HLABAAAA, Preventive & Routine General Dentistry (Exams/Cleanings/Sealants/Fluoride), with a secondary code of HLABAHAK, Desensitization Treatments for Dentin Hypersensitivity. Its NAICS code is 339114 and its SIC code is 3843.