Natural Stacks

What Natural Stacks does

Natural Stacks (legal entity NS 360 Inc.) is a privately held, founder-led nootropic supplement company founded in 2013 by Roy Krebs and headquartered in Seattle, Washington. The company sells science-backed, single-benefit dietary supplements targeting specific neurotransmitter systems — dopamine, serotonin, GABA, and acetylcholine — alongside magnesium-based products, nootropics for focus, and a brain longevity line. Its product portfolio of roughly 30 SKUs is anchored by patented branded ingredients licensed from third-party developers, including Magtein (Magnesium-L-Threonate developed by MIT scientists), Zembrin Kanna Extract (a PDE4 inhibitor), and enfinity Paraxanthine. A core differentiator is the Open Source transparency program, which provides full label disclosure, ingredient traceability, and blockchain-verified third-party lab test results for every batch through a partnership with HealthLoq.

The business operates a dual-channel go-to-market. The primary engine is direct-to-consumer e-commerce on naturalstacks.com with a subscription program offering 20-40% discounts and free shipping, complemented by a Build Your Own Bundle configurator and a Brain Assessment Quiz for lead generation. Secondary distribution includes physical retail placement at Whole Foods Market in the United States and a network of international retail partners across Ireland, the UK, Sweden, the Netherlands, Australia, and Hong Kong, while subscriptions remain US/Canada only. Pricing spans $7.96 for entry-level SKUs to roughly $293 for multi-pack subscriptions, with bundle stacks offering 15% off and new-customer promotions of 50% off first orders. The company also maintains a practitioner referral network of healthcare providers who recommend its products to patients.

The end customer is health-conscious adults aged 25-65 seeking cognitive, sleep, mood, and longevity support without prescription medications. Marketing relies on content (a blog called The Stack), email and SMS, an affiliate program run through Superfiliate, and endorsements from healthcare practitioners and performance figures (a WSOP poker champion, a Memory Grandmaster, and functional medicine doctors). The company is bootstrapped with no disclosed funding rounds or parent company, and operates with 1-10 employees according to firmographic data, suggesting a lean, founder-led operation scaled primarily through cash-flow reinvestment.

Name

Natural Stacks

Legal name

NS 360 Inc.

Website

https://naturalstacks.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

1–10 employees

Short description

Natural Stacks is a privately held, bootstrapped nootropic supplement brand founded in 2013 that sells science-backed cognitive, sleep, mood, and longevity supplements directly to consumers via its website subscription engine and through Whole Foods and international retail partners.

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Food (Health) Supplement Retailers (456191), Drugs and Druggists' Sundries Merchant Wholesalers (4242)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Healthy Aging & Cognitive Support Supplements (CRADAGAM)

akta.pro secondary industries

Specialty Condition Supplements (Sleep, Stress, Heart, Joint, Gut, Immunity) (CRADAGAE), Herbal & Botanical Supplements (CRADAGAD)

Keywords

• Nootropic supplements
• Cognitive enhancement supplements
• Brain health supplements
• Dietary supplement stacks
• Magnesium sleep supplements

Headquarters

HQ city

Lewes

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Marketing or Sales, Technology or R&D

Revenue model

1. Direct E-commerce Sales: Direct-to-consumer sales through naturalstacks.com website. One-time purchase and subscription options. Subscription model with 20-40% discounts drives recurring revenue.
2. Subscription/Recurring Revenue: Subscription program offering 20% off monthly orders, up to 40% off for 6-month subscriptions. Includes free shipping and account support. Drives predictable recurring revenue.
3. Retail/Wholesale Distribution: Products sold through retail partners including Whole Foods Market and international distributors. Revenue through wholesale pricing to retail channels.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels6 records

Core offering

Natural Stacks sells a portfolio of science-backed nootropic and brain-health dietary supplements directly to consumers via its own e-commerce website, with strong emphasis on a subscription model. Products include single-target neurotransmitter support formulas (Dopamine, Serotonin, GABA, Acetylcholine Brain Food), MagTech magnesium supplements featuring patented Magtein, focus nootropics (NEUROFUEL, Smart Caffeine, NeuroAlert), brain longevity formulas (NEUROLIFE, Smart NMN, Smart Resveratrol), and pre-bundled "stacks" combining multiple supplements for synergistic cognitive benefits.

Product overview

Natural Stacks is a nootropics and brain supplement company founded in 2013, offering a portfolio of targeted, single-benefit supplement formulas designed to be combined (stacked) for optimal cognitive performance. The product line centers on the 'Brain Food' line of neurotransmitter support supplements (Dopamine Brain Food™, GABA Brain Food™, Serotonin Brain Food™, Acetylcholine Brain Food™) and the MagTech® magnesium series (Magnesium, Sleep Drink, Hydrate Drink, Cognition Drink). Additional products include nootropics for focus (NEUROFUEL™, Smart Caffeine®, NeuroAlert™), brain longevity (NEUROLIFE™, Smart NMN™, Smart Resveratrol™), and cognitive support (Smart Lion's Mane™, Smart Ginkgo™, Smart Omegas™, Vitamin D3). The company also offers pre-formulated stacks and bundles combining multiple products, subscription options, and emphasizes an 'Open Source' transparency model with third-party lab testing for every batch.

Differentiator

Problem solved

Functional benefit

Brands

• Brain Food™: Line of neurotransmitter-support supplements including Serotonin Brain Food, Dopamine Brain Food, Acetylcholine Brain Food, and GABA Brain Food.
• NEUROFUEL™
• Smart Caffeine®
• MagTech®
• NeuroAlert™
• NEUROLIFE™
• Smart Lion's Mane™
• Smart Omegas™

Products and services

• MagTech® Magnesium Magnesium supplement combining three forms of chelated magnesium (including patented Magtein Magnesium-L-Threonate) for sleep, relaxation, and brain health; designed for adults seeking clinically backed magnesium support.
• Dopamine Brain Food™ Nootropic supplement designed to support the body's natural production of dopamine, promoting mental drive, motivation, focus, and attention for adults seeking productivity and motivation support.
• GABA Brain Food™ Nighttime support supplement formulated to support healthy GABA production for calm, stress reduction, and improved sleep quality.
• Serotonin Brain Food™ Supplement designed to support serotonin production for positive mood, sense of well-being, and occasional stress management.
• Acetylcholine Brain Food™ Nutrient supplement designed to promote acetylcholine production for cognitive function, faster thinking, and memory support.
• NEUROFUEL™ Nootropic Focus and memory nootropic supplement using the CILTEP formula with artichoke leaf extract (luteolin) and Coleus forskohlii (forskolin) to support cAMP signaling for enhanced concentration and learning.
• Smart Caffeine® Caffeine and L-theanine combination supplement for long-lasting energy and attention without jitters, anxiousness, or crash.
• NeuroAlert™ Brain energy and stamina supplement featuring enfinity® Paraxanthine and NADH for sustained alertness without crash or jitters.
• NEUROLIFE™ Brain longevity supplement featuring MitoPrime® L-ergothioneine, berberine, and taurine to help protect and prolong cognitive function.
• NeuroMulti™ Daily cognition essentials supplement providing foundation-level brain nutrition.
• Brain Food™ Stack Comprehensive stack bundle combining Serotonin Brain Food, Dopamine Brain Food, Choline Brain Food, and GABA Brain Food for complete neurotransmitter support from sunrise to sunset.
• Focus & Memory Stack Stack bundle combining NEUROFUEL™ Nootropic and Dopamine Brain Food for enhanced mental focus, motivation, and memory support.
• Sleep & Relaxation Stack Stack bundle combining GABA Brain Food and MagTech Magnesium for deep, restorative sleep and relaxation support.
• Mood & Stress-Relief Stack Stack bundle combining GABA Brain Food and Serotonin Brain Food for calm mind and stress relief support.
• Aging & Longevity Stack Stack bundle combining NeuroLife with other supplements designed to protect and prolong cognitive function.
• Mental Performance Stack™ Stack bundle combining Smart Caffeine and NEUROFUEL Nootropic for optimal brain function and improved sleep.
• MagTech® Sleep Drink Powdered magnesium drink mix featuring three forms of chelated magnesium, glycine, and chamomile for melatonin-free sleep support.
• MagTech® Hydrate Drink Magnesium powdered hydration drink with more magnesium, less salt, and no sugar for cellular hydration support.
• MagTech® Cognition Drink Magnesium drink in Raspberry Lemonade flavor designed to support focus and mental clarity.
• Focus Bites Watermelon Mint fast-acting chewables for clean stimulation and concentration without caffeine crash.
• Mood Bites Citrus Peach chewables designed to support and improve mood over time.
• Mood Magnesium Gummies Gummies featuring Sensoril® Ashwagandha Extract and L-Theanine for stress response support and relaxation.
• Sleep Magnesium Gummies Gummies with Chamomile Flower Extract and Melatonin for deeper, more restful sleep support.
• Smart Lion's Mane™ Neurohealth formula with Lion's Mane designed to support cognitive function, memory, focus, and mood.
• Smart Ginkgo™ Ginkgo supplement combining three high-quality ingredients for sharper, longer-lasting attention and focus.
• Smart Apigenin™ Sleep support supplement derived from chamomile (apigenin) for drifting off faster and improving sleep quality.
• Smart Creatine™ Creatine supplement designed with enhanced absorption for cognitive and physical performance support.
• Smart Omegas™ Plant-based Omega-3 DHA supplement using AvailOm® for brain health, with 200mg of algae-sourced DHA per capsule.
• Smart Resveratrol™ Three-pronged antioxidant formula for healthy aging support.
• Smart NMN™ Advanced NAD+ support supplement with NMN for cellular energy and healthy aging.
• Vitamin D3 w/ Organic Coconut Oil Vitamin D3 supplement with organic coconut oil for enhanced absorption, supporting new cell growth, bone formation, and immune function.
• NEUROFUEL™ Nootropic w/ Zembrin® Enhanced focus nootropic with clinically-tested Zembrin® Kanna Extract for executive function, cognitive flexibility, and mental organization.
• Complete Neuro Stack Comprehensive stack bundle combining NeuroMulti, NeuroAlert, NeuroFuel, and NeuroLife for complete daily brain nutrition.
• Brain Essentials Stack Foundation-level cognitive performance stack bundle combining NeuroMulti and Smart Omegas.
• Performance and Longevity Stack Daily stack bundle for mental performance, brain longevity, and vitality combining NeuroLife and NeuroFuel.
• NEUROFUEL™ Nootropic + Smart Caffeine® Stack Stack bundle combining NEUROFUEL and Smart Caffeine for deep focus, concentration, and energy without jitters or crash.
• Sleep Easy Stack Sleep support stack bundle combining Smart Apigenin, MagTech Magnesium, and GABA Brain Food for calm body and mind.
• Magnesium Gummy Stack Bundle of Mood and Sleep Magnesium Gummies for comprehensive relaxation support with 200mg of elemental magnesium per serving.
• MagTech® Hydrate + Creatine Hydration drink delivering 3,000mg of creatine monohydrate per dose for cellular energy and hydration support.
• MagTech® Drink Stack Bundle of three MagTech drink formulas (Hydrate, Cognition, and Sleep) working in synergy for comprehensive brain support.

Quantifiable outcome

• Magtein shown to reduce brain age by 9 years in placebo-controlled clinical trials
• +3 more outcomes

Named customers5 records

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Five partnerships are on record, tiered core, major and minor.

• MIT Scientists / Magtein Rights HolderscoreTechnology or IntegrationLicensing agreement for Magtein (Magnesium-L-Threonate), a patented form of magnesium developed by MIT scientists including Dr. Liu. This ingredient is featured in MagTech Magnesium products and represents a key product differentiator based on clinical research.
• Zembrin / Kanna Extract SupplierscoreTechnology or IntegrationLicensed use of Zembrin Kanna Extract, a clinically-studied PDE4 inhibitor for cognitive enhancement, featured in NeuroFuel Nootropic products.
• enfinity Paraxanthine SupplierscoreTechnology or IntegrationLicensed use of enfinity Paraxanthine, a patented caffeine metabolite providing clean stimulation without crash, featured in NeuroAlert and Focus Bites.
• Whole Foods MarketmajorChannel Partner/ Reseller/ DistributorMajor retail partner for physical store distribution of Natural Stacks products, including MagTech supplements, in Whole Foods locations across the United States.
• International Retail PartnersminorChannel Partner/ Reseller/ DistributorNetwork of international retail distributors including Powerful (Ireland), Evolution Organics (UK), Upgrit (Sweden), Digiwell, TheStoreHK (Hong Kong), MyDFX (Australia), and Livehelfi (Netherlands).

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• NooCube: DTC nootropic supplement brand targeting focus, memory, and cognitive performance. Direct product-category overlap with Natural Stacks Brain Food and NEUROFUEL lines.
• Mind Lab Pro: Universal nootropic formula positioned for cognitive enhancement, sold via DTC channels. Competes in the same nootropics category with similar premium-ingredient positioning and clinical claims.
• Thesis: Personalized nootropics brand sold DTC with quiz-driven product recommendations. Closely comparable GTM motion (brain/personality quiz → personalized stack) and target consumer (cognitive optimizers).
• Ritual: Premium DTC supplement brand built on transparency, traceability, and clean ingredients. Comparable 'know-what's-in-your-supplement' positioning that mirrors Natural Stacks' Open Source program.
• Onnit: Direct DTC peer selling nootropics and cognitive performance supplements (Alpha BRAIN) to biohacking and health-conscious consumers. Comparable target customer, product category, and brain-stacking philosophy.
• Momentous: Premium supplements brand with practitioner endorsement model and patented-ingredient focus. Comparable premium DTC positioning, practitioner network strategy, and clinical-ingredient sourcing.
• Care/of: Personalized DTC vitamin/supplement brand using quiz-driven recommendations and subscription model. Closely analogous quiz-to-product GTM motion and subscription-first D2C supplement economics.
• Qualia (Neurohacker Collective): Premium nootropic stacks (Qualia Mind, Qualia Focus) targeting biohackers and cognitive-optimization consumers. Direct overlap on stacking concept, premium pricing, and clinical-ingredient positioning.

Broad incumbents

• Athletic Greens (AG1): Larger DTC supplements player with broad nutritional positioning including brain health. Comparable DTC subscription model and premium pricing, but broader category scope rather than nootropics-specific.
• Life Extension: Established longevity and brain-health supplement brand with clinical-ingredient positioning and practitioner credibility. Overlaps on cognitive and aging supplements but operates through catalog/online channels at larger scale.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/naturalstacks
• LinkedInlinkedin.com/company/natural-stacks-inc

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Natural Stacks