What Granalix does

Granalix Bio Technologies Ltd is a privately held Israeli biotechnology company founded in May 2013 as a spin-off from Yissum (Hebrew University of Jerusalem's technology transfer arm) and Hadasit (Hadassah Medical Center's technology transfer arm). The company was co-founded by Prof. Ruth Gabizon, a Hadassah neurology researcher trained under Nobel laureate Stanley Prusiner at UCSF, and Prof. Shlomo Magdassi, a nanotechnology expert with 220+ academic publications from Hebrew University's Casali Center. Granalix commercializes a patented nano-emulsification technology that converts oil-based nutrients into 100% water-soluble nano-droplets, addressing the well-known bioavailability limitations of traditional oil-based dietary supplements. U.S. Patent US10154961 (granted December 2018) and pending European Patent EP2844265A1 protect the core platform.

The company sells three products under two brands through a direct-to-consumer e-commerce channel at granalix.com: GranaGard Nano-Omega 5 capsules (pomegranate seed oil-derived Punicic Acid, $49-$196 for 1-4 month supplies), GranaGard Nano-Omega 5 Drops (40ml liquid format, $77), and NanoGard Omega 3 (fish oil-derived EPA/DHA, $70 for 120 softgels). Manufacturing is outsourced to Ambrosia-SupHerb, an Israeli GMP-, ISO 9001-, ISO 22000-, and HACCP-certified contract manufacturer. Granalix targets health-conscious adults seeking cognitive and antioxidant support, with a primary segment focused on memory and brain health and a secondary segment of antioxidant supplement users. The company cites a Hadassah Ein Kerem clinical trial showing 12% improvement in CVLT-II cognitive memory scores after three months of GranaGard use and claims up to 4x greater tissue absorption versus standard fish oil.

The go-to-market is exclusively DTC: an owned e-commerce storefront, email marketing, an affiliate program, and paid digital advertising (Outbrain, Taboola, Facebook), with shipping to the US, Canada, and Israel. Products carry multiple compliance certifications including FDA GRAS, Kosher Parve, Halal, and GOED Seal of Quality for Omega-3. The company has disclosed no external venture funding rounds and operates with minimal named personnel beyond its two co-founders and one scientific consultant, indicating a bootstrapped, capital-constrained operating profile.

Name

Granalix

Legal name

Granalix Bio Technologies Ltd

Website

https://granalix.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

1–10 employees

Short description

Granalix is an Israeli biotech company that sells patented nano-emulsified dietary supplements (GranaGard Nano-Omega 5, NanoGard Omega 3, GranaGard Drops) direct-to-consumer via granalix.com, targeting health-conscious adults seeking cognitive and antioxidant support.

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Food (Health) Supplement Retailers (456191)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Herbal & Botanical Supplements (CRADAGAD)

akta.pro secondary industries

Delivery Systems & Encapsulation (Microencapsulation, Liposomes, Emulsions, Beadlets, Spray-Dried) (AFAJAKAL), Encapsulation & Emulsified Delivery Systems (Spray-dried emulsions, Lipid microencapsulation) (AFAJACAL), Fats, Oils & Lipid Ingredients (Specialty Oils, MCTs, Structured Lipids) (CRADAOAL), Lipid-Based Emulsions & Encapsulated Oils (Spray-Dried Oils, Microencapsulation) (AFAJALAM)

Keywords

• Nanotechnology dietary supplements
• Cognitive health supplements
• Omega-5 supplements
• Omega-3 supplements
• Pomegranate seed oil supplements

Headquarters

HQ city

Jerusalem

HQ country

Israel

HQ region

Middle East

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Operations, Supply Chain, Technology or R&D, Marketing or Sales, Personnel

Revenue model

1. Direct Product Sales: Revenue generated from direct-to-consumer sales of dietary supplements through the company's e-commerce website. Products include GranaGard Nano-Omega 5 capsules, NanoGard Omega 3 softgels, and GranaGard Nano-Omega 5 Drops. Sales are made in single purchases and through subscription options with multi-month supplies at discounted rates.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

Granalix develops and sells patented nanotechnology-based dietary supplements direct-to-consumers via its e-commerce website. The portfolio includes GranaGard Nano-Omega 5 softgel capsules (pomegranate seed oil), GranaGard Nano-Omega 5 Drops (liquid), and NanoGard Omega 3 softgels (fish oil). All products use a proprietary nano-emulsification platform that converts oil-based nutrients into 100% water-soluble nano-droplets for superior absorption and bioavailability, and are backed by peer-reviewed research and a human clinical trial at Hadassah Medical Center.

Product overview

Granalix is a biotechnology company specializing in nanotechnology-enhanced dietary supplements. The company offers three products under two brands: GranaGard (pomegranate seed oil/Omega-5 based) and NanoGard (fish oil/Omega-3 based). Both product lines utilize the same patented nanotech formula developed at the Hebrew University of Jerusalem, which converts oil-based supplements into water-soluble nano-droplets for dramatically improved absorption and bioavailability. GranaGard targets cognitive health with Omega-5 (Punicic Acid) while NanoGard provides essential Omega-3 fatty acids (EPA/DHA) for overall wellness. The company was founded in May 2013 by Prof. Ruth Gabizon (Hadassah Medical Center) and Prof. Shlomo Magdassi (Hebrew University), with products manufactured by Ambrosia-SupHerb in Israel.

Differentiator

Problem solved

Functional benefit

Brands

• GranaGard: Patented nanotechnology-based dietary supplement containing Nano-Omega 5 (Punicic Acid) from pomegranate seed oil for brain health and cognitive support.
• NanoGard

Products and services

• GranaGard Nano-Omega 5 Patented nanotechnology-based dietary supplement in softgel capsule form containing pomegranate seed oil (Omega-5 / Punicic Acid) for cognitive health support. The nano-emulsification formula converts the oil into 100% water-soluble nano-droplets for maximum absorption and high bioavailability. Sold in 1, 2, 3, and 4 month supply packages priced $49 to $196, targeting health-conscious adults seeking brain-health and memory support.
• GranaGard Nano-Omega 5 Drops Liquid drop formulation of the patented GranaGard nano-Omega 5 (Punicic Acid) supplement. Contains 40ml per bottle with 250mg pomegranate seed oil per daily serving of 33 drops. Uses the same water-soluble nano-emulsification technology for optimal absorption. Priced at $77 per bottle and targeted at consumers preferring a liquid delivery format.
• NanoGard Omega 3 Dietary supplement using the same patented nano-emulsification technology as GranaGard, but with fish oil as the source of Omega-3 essential fatty acids (EPA and DHA). The nanotechnology enables up to four times greater absorption in body tissues compared to regular fish oil. Sold as a 120 softgel bottle priced at $70 for general wellness and essential fatty acid supplementation.

Quantifiable outcome

• 12% improvement in CVLT-II cognitive memory test scores after 3 months of GranaGard use in human clinical trial
• +2 more outcomes

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature3 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• Yissum (Hebrew University Technology Transfer)coreStrategic or Co-development Partner · 1 May 2013Yissum is the technology transfer company of the Hebrew University of Jerusalem. Granalix was established as a subsidiary of Yissum, enabling commercialization of nanotech research developed at the university. The partnership provides access to proprietary nanotechnology expertise and intellectual property from the Hebrew University.
• Hadasit (Hadassah Medical Center Technology Transfer)coreStrategic or Co-development Partner · 1 May 2013Hadasit is the technology transfer company of Hadassah Medical Center. Granalix was established as a subsidiary of Hadasit, enabling commercialization of neurological research developed at Hadassah Hospital. The partnership provides access to clinical research expertise and medical knowledge.
• Ambrosia-SupHerbcoreOEM/ Whitelabel/ Licensing PartnerIsrael's leading manufacturer of advanced nutritional supplements. Manufactures GranaGard and NanoGard products exclusively for Granalix under strict quality controls. Factory meets all requirements set by Ministry of Health Israel and holds ISO 9001, ISO 22000, GMP, and HACCP certifications.
• Hadassah Ein Kerem University HospitalcoreStrategic or Co-development PartnerClinical research partner for human trials of GranaGard products. Neurology department conducts clinical trials under Prof. Dimitrius Karussis. Trial approved by Helsinki Committee for Clinical Trials in Humans. Also involved in research with Prof. Ruth Gabizon's laboratory.
• Hebrew University of JerusalemcoreStrategic or Co-development PartnerAcademic research partner where Prof. Shlomo Magdassi's laboratory conducts nanotechnology research and product testing. Casali Center for Applied Chemistry provides expertise in nanomaterials creation and application. Research published in peer-reviewed scientific journals.
• Ichilov HospitalminorStrategic or Co-development PartnerMedical institution collaborating on clinical trials and research related to GranaGard products, in close collaboration with neurology departments.
• Rambam HospitalminorStrategic or Co-development PartnerMedical institution collaborating on neuropsychology research related to GranaGard products.

Scale indicators4 records

Recent moves7 records

Expansion highlights5 records

Emerging players

• Onnit: Brain health and cognitive performance supplement brand combining nootropics with wellness positioning. Comparable to Granalix in DTC marketing approach and cognitive health customer focus.
• Designs for Health: Practitioner-channel supplement brand with cognitive and metabolic health formulations. Comparable to Granalix in evidence-based positioning and cognitive health focus.

Direct peers

• Nordic Naturals: Leading direct-to-consumer and retail omega-3 supplement brand offering fish oil and other lipid-based supplements. Directly comparable to Granalix's NanoGard Omega-3 product line in target customer, product format, and premium positioning strategy.
• Jarrow Formulas: Supplement brand offering premium omega-3s and cognitive health products across DTC and retail channels. Comparable to Granalix's product positioning and NO-Omega 3 product line.
• Carlson Labs: Long-standing omega-3 supplement brand with broad retail and DTC distribution. Comparable to Granalix in fish oil sourcing and GOED quality member status, with more mature market presence.
• Quicksilver Scientific: Specializes in liposomal and nano-emulsified supplement delivery systems for omega-3s, glutathione, vitamin C, and other nutrients. The most direct technology comparable to Granalix's patented nano-emulsification platform.
• Mind Lab Pro: Premium nootropic supplement brand targeting cognitive performance, memory, and brain health. Directly comparable to Granalix's GranaGard in target customer (cognitive health seekers) and DTC premium positioning.

Broad incumbents

• NOW Foods: Mass-market supplement manufacturer with broad omega-3 and cognitive health product lines. Comparable to Granalix in product categories but at significantly lower price points and with broader retail distribution.
• Life Extension: Large, established supplement brand with deep cognitive health and omega-3 formulations supported by extensive clinical references. Competes in the same customer segment as Granalix but with a much broader product portfolio and retail presence.
• Pure Encapsulations: Practitioner-grade supplement brand offering cognitive health and omega-3 formulations. Competes in the evidence-based supplement market that Granalix targets with clinical trial backing.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/granalix
• LinkedInlinkedin.com/company/granalix-bio-technologies-ltd

Compliance8 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Granalix