The Blood Connection

What The Blood Connection does

The Blood Connection (TBC) is a nonprofit community blood center founded in 1962 in Greenville, South Carolina, and headquartered at 1099 Bracken Road, Piedmont, SC. The organization collects, processes, and supplies blood products — whole blood, platelets, plasma, and double red cells (via Alyx automated collection) — through 22+ fixed donor centers and a mobile bloodmobile fleet serving North Carolina, South Carolina, Virginia, and Georgia. TBC supplies 145+ hospitals and health systems across these four states, including sole-supplier arrangements with major regional systems such as Prisma Health, Carilion Clinic, Mission Health, ECU Health, Grand Strand Health, and Memorial Health.

TBC's core technology stack centers on physical collection and processing infrastructure (Alyx apheresis machines, leukapheresis capability for Dendreon's PROVENGE prostate cancer treatment, FDA-registered laboratory operations), complemented by digital donor-facing tools (TBC Express Pass online pre-registration, donor portal) and hospital-facing platforms (TBC Direct portal, BloodHub ordering integration, UNIT FINDER inventory management). Donor engagement is supported by the TBC Rewards Program — a points-based system (with Platelet Plus tiered variant offering $25-$40 per donation) fulfilled via Tango Card eGift cards — and by community programs including School Programs (with $500 grants for 30+ donation drives), Faith at Work, and sports team partnerships (Asheville Tourists, Charleston River Dogs).

The business model is service-based: TBC operates as a 501(c)(3) tax-exempt nonprofit (IRS Letter of Determination, FDA registration FDA2830) and generates revenue through hospital service agreements for blood products. There is no direct consumer pricing — blood donation is free to donors, and compensation flows from healthcare partners. GTM combines event-driven acquisition (community blood drives at schools, businesses, places of worship, and high-profile partnerships including MrBeast's Beast Philanthropy) with community-led retention through fixed donor centers. The customer base is dual-sided: individual donors (supply side) and hospital/healthcare systems (demand side), with hospital contracts increasingly structured as sole-supplier exclusivity arrangements.

Name

The Blood Connection

Legal name

The Blood Connection, Incorporated

Website

https://thebloodconnection.org

Company type

Private

Founded year

1962

Operating status

Operating

Headcount range

501–1,000 employees

Short description

The Blood Connection is a 501(c)(3) nonprofit community blood center founded in 1962 that collects, processes, and supplies whole blood, platelets, plasma, and double red cells to 145+ hospitals across North Carolina, South Carolina, Virginia, and Georgia through 22+ donor centers and a mobile fleet.

Ownership category

akta.pro rank

Product category

Blood & Biologics Supply Services

NAICS

Blood and Organ Banks (621991)

akta.pro primary industry

Blood, Organ & Tissue Donation Organizations (BPAGACAJ)

akta.pro secondary industry

Transfusion Medicine & Immunohematology (Blood Bank) (HLAFAMAG)

Keywords

• Community blood center
• Blood donation services
• Hospital blood supply
• Apheresis collection services
• Blood component processing

Headquarters

HQ city

Piedmont

HQ country

United States

HQ region

North America

Offices23 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Infrastructure, Marketing or Sales, Technology or R&D

Revenue model

1. Blood Product Supply to Hospitals: TBC supplies blood products and services to over 145 hospitals across North Carolina, South Carolina, Virginia, and Georgia. As a nonprofit community blood center, revenue is generated through hospital service agreements for blood products and related services.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

The Blood Connection is a nonprofit community blood center that collects whole blood, platelets, plasma, and double red cells from volunteer donors at fixed donor centers and mobile blood drives across four states. Collected products are processed and supplied to 145+ hospitals across North Carolina, South Carolina, Virginia, and Georgia under service agreements. Donor recruitment is supported by community outreach, school programs, faith-based initiatives, and a points-based rewards program.

Product overview

The Blood Connection is a nonprofit community blood center offering a unified blood donation service platform. The core offering consists of blood collection services through four donation types (whole blood, platelets, plasma, and double red cells via Alyx) at permanent Community Blood Centers and mobile blood drives across North Carolina, South Carolina, Georgia, and Virginia. This is supported by the TBC Rewards Program, which incentivizes donations through points redeemable for eGift cards via Tango Card integration. Hospital services include TBC Direct for blood ordering and UNIT FINDER for inventory management. Supplementary programs include School Programs offering grants for blood drives and the Platelet Plus tiered rewards module for frequent platelet donors.

Differentiator

Problem solved

Functional benefit

Quantifiable outcome

• Each blood donation can help save up to 3 lives
• +2 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

Feature3 records

Partnerships

33 partnerships are on record, tiered flagship, core and minor.

• Beast Philanthropy (MrBeast/Jimmy Donaldson)flagshipGTM or Marketing Partner · 17 June 2026Beast Philanthropy, the charitable organization founded by YouTube creator Jimmy Donaldson (MrBeast), partnered with TBC to host a large-scale blood drive at the Greenville Convention Center. The initiative leverages MrBeast's 1.1 billion+ follower reach to boost donor participation, aiming to collect enough blood to save up to 1,000 lives in one day.
• Sovah Health – DanvillecoreStrategic or Co-development Partner · 1 October 2025The Blood Connection assumed operations of the Sovah Health – Danville Blood Donor Center on October 1, 2025, becoming the sole blood supplier for Sovah Health – Danville. This marked TBC's first permanent location in Southside Virginia.
• Asheville TouristscoreGTM or Marketing PartnerLifesaver League partnership bringing the excitement of game day into TBC's Asheville Community Blood Center for Center Day events. Donors receive exclusive jerseys and game tickets as thank-you incentives. Nearly 100 donors participated in the June 2026 Center Day event.
• Charleston River DogsminorGTM or Marketing PartnerPartnership with the Charleston River Dogs minor league baseball team for community engagement and blood drive events.
• ECU HealthcoreStrategic or Co-development PartnerTBC serves as the blood provider for Eastern North Carolina through ECU Health Medical Center partnership in Greenville, NC.
• Mission HealthcoreStrategic or Co-development PartnerTBC is the blood provider of choice for Western North Carolina's Mission Health, including Mission Hospital and Transylvania Regional Hospital in Asheville and Hendersonville.
• Carilion CliniccoreStrategic or Co-development PartnerTBC partnered with Carilion Clinic and became the sole provider of all blood products to Carilion in the Roanoke, Virginia area.
• WakeMed HealthcoreStrategic or Co-development PartnerBlood supply partnership with WakeMed Health system serving the Wake Forest area in North Carolina.
• UNC HealthcarecoreStrategic or Co-development PartnerCommunity partnership with UNC Healthcare for blood supply to the Wake Forest region.
• Prisma HealthcoreStrategic or Co-development PartnerMajor hospital system partnership in South Carolina Upstate. TBC has provided blood to Prisma Health hospitals, air medical services, and emergency management services for over 60 years.
• Bon SecourscoreStrategic or Co-development PartnerPartnership with Bon Secours in the Greenville, SC area for hospital blood supply.
• Spartanburg Regional HealthcarecoreStrategic or Co-development PartnerBlood supply partnership with Spartanburg Regional Healthcare system in South Carolina.
• AnMed HealthcoreStrategic or Co-development PartnerPartnership with AnMed Health serving Anderson County, SC. TBC provides blood to the hospital system, emergency management services, and air medical transport.
• McLeod HealthcoreStrategic or Co-development PartnerBlood supply partnership with McLeod Health serving the Florence, SC area.
• Trident HealthcoreStrategic or Co-development PartnerContinued partnership with Trident Health in Charleston, SC for blood supply.
• Prisma Health Baptist Easley HospitalcoreStrategic or Co-development PartnerPartnership with Prisma Health Baptist Easley Hospital in Easley, SC. TBC was the first in SC to use lifesaving blood transfusion technology with this hospital.
• Memorial Health University Medical CentercoreStrategic or Co-development PartnerExclusive partnership with Memorial Health University Medical Center as the sole provider of lifesaving blood products for Savannah, GA area.
• Joseph M. Still Burn CentercoreStrategic or Co-development PartnerBlood supply for the Joseph M. Still Burn Center and Doctors Hospital in the greater Augusta and Evans, GA areas.
• Piedmont Athens RegionalcoreStrategic or Co-development PartnerHealthcare partner in Northeast Georgia for blood supply services.
• American Medical Response (Atlanta)coreStrategic or Co-development PartnerBlood supply partnership with American Medical Response in the Atlanta, GA area.
• Fairview Park Hospital (Dublin, GA)minorStrategic or Co-development PartnerHealthcare partner in the Dublin, GA area for blood supply.
• Memorial Health Meadows HospitalminorStrategic or Co-development PartnerHealthcare partner in the Vidalia, GA area for blood supply.
• Memorial Health SatillaminorStrategic or Co-development PartnerHealthcare partner in the Waycross, GA area for blood supply.
• AdventHealthcoreStrategic or Co-development PartnerHealthcare partner in Western North Carolina for blood supply.
• Onslow Memorial HospitalcoreStrategic or Co-development PartnerHealthcare partner in North Carolina for blood supply.
• CarolinaEast Medical CentercoreStrategic or Co-development PartnerHealthcare partner in North Carolina for blood supply.
• Roper St. Francis HealthcarecoreStrategic or Co-development PartnerHealthcare partner along the South Carolina coast for blood supply.
• Lexington Medical CentercoreStrategic or Co-development PartnerHealthcare partner in the South Carolina Midlands (Columbia area) for blood supply.
• Conway Medical CentercoreStrategic or Co-development PartnerHealthcare partner in the Grand Strand area of SC for blood supply.
• Tidelands HealthcoreStrategic or Co-development PartnerHealthcare partner in the Grand Strand area of SC for blood supply.
• Grand Strand HealthcoreStrategic or Co-development PartnerChosen as sole blood provider for Grand Strand Health in Myrtle Beach, SC.
• Atrium Health Wake ForestcoreStrategic or Co-development PartnerHealthcare partner in North Carolina for blood supply.
• Tango Card, Inc.coreTechnology or IntegrationThird-party reward fulfillment service provider for the TBC Rewards Program. Handles points redemption and eGift card delivery through their platform.

Scale indicators6 records

Recent moves7 records

Expansion highlights5 records

Broad incumbents

• American Red Cross: The largest U.S. blood collection organization, operating a national footprint of donor centers, mobile blood drives, and hospital supply agreements. Directly comparable to TBC as a community/blood center serving hospitals, but at substantially greater scale and geographic reach.
• Vitalant: One of the largest nonprofit blood collectors in the U.S., serving hospitals across multiple states. Operates the same hospital supply + community donor center model as TBC, with broader regional reach into the West and Midwest.

Direct peers

• OneBlood: Large regional nonprofit blood center serving Florida, Georgia, Alabama, and the Carolinas. Closest direct comparable to TBC given similar regional scope, hospital partnership model, and overlapping territory in Georgia.
• New York Blood Center: Major nonprofit community blood center serving hospitals in the New York metropolitan area and beyond. Operates the same blood collection, processing, and hospital distribution model as TBC, but at a much larger scale and different geography.
• Carter BloodCare: Nonprofit regional blood center serving hospitals across Texas. Mirrors TBC's model of operating fixed donor centers, mobile blood drives, and exclusive hospital supply relationships, though concentrated in a different geography.
• LifeSouth Community Blood Centers: Nonprofit community blood center headquartered in Gainesville, FL, serving hospitals across the Southeastern U.S. Closely comparable regional blood center with overlapping Carolinas/Georgia geography and similar hospital supply + community donor operations.
• Versiti: Nonprofit blood center and transfusion medicine organization serving hospitals across the Midwest. Operates donor centers, blood drives, and specialized diagnostic/blood product services — a structurally similar regional blood center model.
• Gulf Coast Regional Blood Center: Nonprofit community blood center serving hospitals in the Texas Gulf Coast region. Same operating model as TBC: donor centers, mobile blood drives, hospital supply contracts, and community outreach.
• Hoxworth Blood Center (University of Cincinnati): Regional blood center affiliated with the University of Cincinnati, serving hospitals in Ohio, Kentucky, and Indiana. Operates the same nonprofit blood collection and hospital distribution model as TBC.

Others

• Dendreon (PROVENGE): Manufacturer of the PROVENGE prostate cancer immunotherapy, for which TBC performs leukapheresis collections at its Spartanburg center. Adjacent counterparty rather than a direct competitor, but illustrates TBC's reach into specialty cell collection services.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/bloodconnection
• YouTubeyoutube.com/c/TheBloodConnectiontv
• Facebookfacebook.com/TheBloodConnection
• LinkedInlinkedin.com/company/thebloodconnection
• Instagraminstagram.com/thebloodconnection

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about The Blood Connection