Sycamore Biopharma

What Sycamore Biopharma does

Sycamore Biopharma is a privately held, U.S.-based botanical extraction and CBD wellness company founded in 2018 in Charleston, South Carolina. It operates a cGMP-compliant extraction facility in West Columbia, SC, opened in Spring 2020, using Supercritical CO2 extraction and wiped-film distillation to produce medical-grade CBD inputs, with current operational contact in Melbourne, FL. The company sells finished products through five trademarked sub-brands — Aligned (tinctures, topicals, soft gels, gummies), Embraced (CBD-charged compression sleeves and socks with motion-release transdermal microencapsulation, paired with Recharged refill spray), Drift (CBD:CBN sleep aids), Right Coast (Delta-8 and Nano Delta-9 THC edibles), and GAMEDAY RELEAF (athletic recovery products) — under a direct-to-consumer e-commerce model at sycamorebp.com with subscription billing at 10–20% discounts.

The core technical differentiators are the patent-pending Embraced CBD-Charged transdermal microencapsulation system, which delivers CBD and botanical blends through compression wear via motion-activated rupture of microcapsules, and a nano-emulsification process for water-soluble Delta-9 THC that the company claims improves bioavailability. The company also references a 10:1 CBD:THC ratio formulation for inflammation and recovery, grounded in peer-reviewed research, and maintains a public third-party lab testing/COA transparency posture. Pricing across the SKU set ranges from approximately $19.95 (Recharged refill spray) to $99.99 (3000mg full-spectrum tincture), with most products in the $29.95–$49.95 range.

The go-to-market is direct-to-consumer e-commerce with nationwide USPS shipping, supported by a content-marketing blog, social presence (Instagram, Facebook, YouTube, X, TikTok), email marketing, and verified customer reviews. A regional physical presence is referenced in the Melbourne, FL area, and a single B2B healthcare reference is OrthoSC Pain Management. The company has 51–100 employees, is privately held with no disclosed institutional backing beyond a $500,000 funding round in December 2019, and generates revenue through one-time purchases plus a recurring subscription layer across both CBD-only and hemp-derived THC product lines.

Name

Sycamore Biopharma

Legal name

Sycamore Biopharma, Inc.

Website

https://sycamorebp.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

51–100 employees

Short description

Sycamore Biopharma is a privately held, U.S.-based botanical extraction and CBD wellness company operating a cGMP facility and selling medical-grade CBD and hemp-derived THC products directly to consumers via e-commerce, anchored by a patented transdermal compression-wear delivery system and five trademarked sub-brands.

Ownership category

akta.pro rank

Product category

Cannabinoid Wellness Products

NAICS

Medicinal and Botanical Manufacturing (325411), Nonchocolate Confectionery Manufacturing (31134)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

CBD/Hemp Wellness & Supplements Retail (CRANAHAC)

akta.pro secondary industries

CBD/Hemp Specialty Stores (Tinctures, Oils, Edibles) (CRANAHAA), CBD/Hemp Topicals & Beauty Retail (CRANAHAB)

Keywords

• Cbd wellness products
• Hemp extraction
• Cannabinoid topicals
• Thc edibles
• Compression wear

Headquarters

HQ city

Columbia

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Marketing or Sales, Operations

Revenue model

1. E-commerce Product Sales: Direct-to-consumer sales of CBD wellness products including tinctures, gummies, topicals, and compression wear through sycamorebp.com. One-time purchase and subscription options available with 10-20% subscription discounts.
2. Subscription/Recurring Revenue: Subscription model offering recurring product deliveries billed monthly or quarterly with up to 20% discount. Includes enrollment, cancellation policies, and reactivation options.
3. Hardware Products: Sale of physical products including Embraced compression sleeves and socks with integrated CBD delivery systems, and Recharged refill sprays.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels6 records

Core offering

Sycamore Biopharma manufactures and sells medical-grade CBD and cannabinoid wellness products, including tinctures, gummies, topicals, and proprietary CBD-charged compression sleeves and socks. The company operates a cGMP-compliant extraction facility using Supercritical CO2 extraction and wiped-film distillation, and sells its products direct-to-consumer via its e-commerce site with one-time and subscription purchasing.

Product overview

Sycamore BioPharma is a natural products processing facility specializing in botanical extracts and sustainable plant-based CBD products. The company operates as a single unified product portfolio organized around CBD wellness solutions, leveraging advanced Supercritical CO2 extraction and wiped-film distillation technologies. The product line comprises five interconnected sub-brands: (1) Aligned - full-spectrum and isolate CBD tinctures, topicals (lotion and roll-on), soft gels, and gummies; (2) Embraced - patent-pending CBD-charged compression wear (knee sleeve, elbow sleeve, sock system) using motion-release microencapsulation technology paired with Recharged CBD refill spray; (3) Drift - CBN-based sleep aid tinctures and gummies; (4) Right Coast - Delta-8 and Nano Delta-9 THC edible gummies; and (5) GAMEDAY RELEAF - athletic recovery-focused gummies and lotions with CBD:THC ratios. All products undergo third-party laboratory testing for purity and potency verification.

Differentiator

Problem solved

Functional benefit

Brands

• Right Coast Edibles: Sub-brand for Delta-8 and Delta-9 THC edible gummies including Nano-Tech formulations
• Embraced
• Aligned
• Drift
• GAMEDAY RELEAF
• Recharged

Products and services

• Aligned Full-Spectrum CBD Tincture (1500mg)

Quantifiable outcome

• Products contain specific cannabinoid dosages verified by third-party testing (e.g., 2000mg CBD in lotions, specific CBD:THC ratios in gummies)

Named customers2 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators3 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• Joy Organics: Family-run CBD brand selling tinctures, gummies, topicals, and softgels through DTC e-commerce. Comparable in scale, organic/CBD positioning, and direct-to-consumer subscription model.
• Lazarus Naturals: Vertically integrated CBD brand with tinctures, topicals, capsules, and edibles sold DTC. Comparable as a vertically integrated, value-priced CBD wellness competitor with similar product breadth.
• Medterra: CBD wellness brand with isolates, sleep, immunity and topical lines distributed DTC and through retail. Comparable product architecture, cGMP positioning, and healthcare-adjacent branding.
• CBDistillery: DTC-first CBD brand with full-spectrum tinctures, isolates, gummies, topicals, and sleep formulations. Closely comparable on product breadth, value pricing, and DTC subscription approach.
• cbdMD: Public CBD brand offering tinctures, gummies, topicals, sleep aids, and recovery products via DTC subscription. Directly comparable SKU mix (CBD oils, gummies, topicals, sleep), pricing structure, and DTC subscription model.
• Green Roads: Pharmacist-formulated CBD brand offering tinctures, topicals, gummies, and sleep aids through DTC and retail. Comparable across product formats and wellness-focused positioning.
• Koi CBD: CBD and hemp-THC brand with vapes, gummies, tinctures, and topicals distributed wholesale and DTC. Comparable product breadth including Delta-8/THC-forward SKUs and the broader hemp cannabinoid positioning.
• Level Select / Select CBD: Sports-recovery focused CBD brand with topicals, roll-ons, and tinctures sold through fitness and retail channels. Comparable on the athletic-recovery positioning embodied in Sycamore's GAMEDAY RELEAF line.
• Highline Wellness: CBD wellness brand with THC-free and THC-forward gummies, oils, and topicals sold DTC. Comparable on sub-brand segmentation, THC gummy line (Right Coast vs Highline's THC products), and subscription pricing.

Broad incumbents

• Charlotte's Web Holdings: Largest U.S. CBD wellness brand with broad tincture, topical, gummy, and pet lines sold DTC and through mass retail. Comparable because it competes head-to-head in CBD tinctures, topicals, and gummies targeting the same wellness consumers.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/sycamorebiophrm
• YouTubeyoutube.com/channel/UCjQ4j0BwVc1jXWRYpUz5sXA
• Facebookfacebook.com/sycamorebiopharma
• Instagraminstagram.com/sycamorebiopharma
• TikToktiktok.com/@sycamorebiopharma
• LinkedInlinkedin.com/company/sycamore-biopharma

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds1 record

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Sycamore Biopharma